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Médecins Sans Frontières (MSF) does currently not have dedicated decision-making support for their in-country inventory allocation and is exploring how such decision support framework could be designed to enhance their supply chain operations. The purpose of this thesis is thus to develop a structured framework for country-level inventory allocation decision-making at MSF.To fulfil the purpose t
The selective separation of glycoproteins is essential in biomarker discovery, glycoprotein profiling and analysis. Glycosylation of proteins has a major impact on their structure and function. The heterogeneity of glycosylation patterns makes the glycomic profiling extensive, but nonetheless of upmost importance for the deeper understanding of metabolic pathways, cell signalling and the impact of
Solanum tuberosum (Potato) is a cool-season, short-day crop that tuberize effectively at temperatures between 15°C-19°C and at a day length of about 12 hours. These environmental requirements pose a moderate challenge to potato cultivar in different region globally. In Northern Europe, summers are characterized by the prolonged daylight and temperature that frequently exceed 19℃. Such conditions c
With the rapid evolution of semiconductor technology and the growing demand for high-performance, low-power System-on-Chip solutions, the design of efficient and scalable on-chip interconnect architectures has become a critical challenge in modern ASIC development. This thesis focuses on design space exploration of replacing multiple ARM CoreLink NIC-400 crossbar-based interconnects with a unified
The recent years spread of misinformation and the rise of post-truth politics have challenged the role of public service media in democratic societies. This thesis explores how the Nordic public service broadcasters – SVT, NRK, DR, RÚV and Yle – position themselves in relation to disinformation, misinformation, and post-truth. Through a qualitative, thematic analysis of their annual reports from 2
Geographical peripheries have long faced marginalization and degradation, enhanced by global trends such as urbanisation. Recently, their revitalization has gained urgency within sustainability discourse, seen as key to achieving global sustainable development. Yet, interventions often focus narrowly on economic recovery, overlooking the social dimension, particularly social cohesion, which is ess
The purpose of this thesis is to enrich our understanding of micro-level internal legal culture by examining how Indonesian legislative lawyers navigate tensions between legal principles and political pressures. The focus is on civil servants within the Coordinating Ministry for Human Development and Cultural Affairs who are tasked with law-making processes, such as drafting, negotiating, and
AI-genererade verk har ökat snabbt under det senaste årtiondet och skakat om EU:s immaterialrättsliga landskap. Tack vare dessa intelligenta system kan individer idag skapa verk som överträffar mänskligt hantverk på bara några minuter. Verk som utnyttjar AI, särskilt autonoma produkter, utmanar de trad-itionella uppfattningar som upphovsrättslagstiftningen bygger på. Frågan om dessa verk kan erhål
Thioflavin T (ThT) is widely used as a fluorescent probe for amyloid fibrils, yet its fluorescence can also be enhanced in non-fibrillar systems. Here, the photophysical behaviour of ThT was investigated in sodium dodecyl sulfate (SDS), sucrose laurate (SL), sodium caprate (C10), and lanreotide-containing assemblies across acetate (pH 4.0), phosphate (pH 7.4), and Gly-Gly (pH 8.5) buffers using UV
Small interfering RNAs (siRNAs) are a rapidly growing class of oligonucleotide therapeutics that modulate gene expression by inducing targeted mRNA degradation. siRNAs are potent and their effect is long-lasting, making them promising candidates for chronic neurodegenerative disease. However, siRNAs can elicit both on- and off-target toxicity, and while acute neurotoxicity has been characterized,
Early diagnosis of colorectal cancer (CRC) is crucial for successful treatment and mortality reduction. In this regard, blood-based tests play an indispensable role. Current research is focused on molecules actively secreted by tumor cells into small extracellular vesicles (EVs). This four-phase study included 613 CRC patients, 446 controls, and 120 precancerous lesions. High-throughput transcript
To achieve established climate objectives, Sweden must effectively target its carbon-intensive steel industry. This study offers a social perspective on the Swedish steel industry's decarbonization, exploring how workers’ identities shape their experience of the transition. Social identity theory is utilised to explore what elements shape steelworkers’ collective and occupational identities in
Currently, many Global South countries face an unprecedented debt crisis with large portions of their spending going to debt repayments. This financial restrain hinders their capacity to address basic needs and ecological challenges, particularly as climate change exacerbates vulnerabilities. To provide a solution for this, The Nature Conservancy (TNC) launched their Nature Bonds Program aimed at
Due to the intensifying impacts of climate change, accurate estimation of global carbon stocks is crucial, with aboveground vegetation biomass representing a significant carbon reservoir. Savannahs, which cover approximately 50% of the African continent, play a vital role in carbon storage, as trees within these ecosystems contribute substantially to the continent’s total carbon stocks. Estimating
The discussion of human activities exploiting natural resources and their environmental impact has gained more traction throughout the past decade. Especially the role corporations play in these developments has caused a shift within corporate strategic considerations. As a result, today, many companies assume increasing responsibility to improve their sustainability performance. Large, internatio
The design of the cost model is motivated by the need of the customer to optimize its energy consumption and maximize the savings. Therefore, this tool will be able to manage the data from both power (geothermal heat pumps) and heating (district heating) systems, as well as outdoor temperatures, energy demand and other inputs, and determine which one is more feasible for every hour of the year. Al
The Brundtland report envisioned three sustainable dimensions for development: economic growth, ecological balance, and social inclusion with the aim to incorporate these dimensions into local, national, and global plans for sustainable development. In recent years, discussions about our society’s competitiveness and whether the three dimensions of sustainable development include all aspects of ou
Research aim: The thesis aims to research how higher education professionals perceive internal communication as a mean for knowledge-sharing within their workplace, and how it can support organizational learning. Theoretical framework and literature review: The theoretical framework applied, address and discuss the connection between internal communication, organizational learning, single- and do
Purpose - A general purpose of this thesis can be defined as to examine and evaluate the possibilities to solve the problem with fluctuating demand on spare parts from the local sales subsidiaries in the three big markets in Europe. A secondary, more specific, purpose of this thesis is to investigate what the possibilities are to implement direct distribution of spare parts to these countri
