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Apolipoprotein M (ApoM) is a sphingosine 1-phosphate (S1P) carrier involved in the regulation of S1P. Signaling pathways involving sphingosine kinases (SphKs) and S1P-S1P receptors (S1PRs) play important roles in the oncogenesis of multiple cancers including non-small cell lung cancer (NSCLC). In the present study we have clarified the potential roles of ApoM on the oncogenesis process of NSCLC ce
The aim of the study was to explore trajectories of breathlessness intensity by function and life-limiting illness diagnosis in the last 3 weeks of life in palliative care patients. A prospective, consecutive cohort study obtained point-of-care data of patients of Silver Chain Hospice Care Service (Perth, Australia) over the period 2011–2014 (n=6801; 51494 data-points). Breathlessness intensity (0
We report new time-resolved laser-induced fluorescence lifetime measurements for 22 highly excited even-parity levels in singly ionized yttrium (Y II). To populate these levels belonging to the configurations 4d6s, 5s6s 4d5d, 5p2, 4d7s and 4d6d, a two-step laser excitation technique was used. Our previous pseudo-relativistic Hartree-Fock model (Biémont et al. 2011) was improved by extending the co
Cortical interneuron deficiencies, particularly involving the somatostatin (SST) subtypes, contribute to neurological and neuropsychiatric disorders. These interneurons are difficult to derive in vitro from human embryonic stem cells (hESCs) due to their late embryonic development and dependence on glial interaction. To this end, we developed a three-dimensional co-culture model of hESC-derived ne
ObjectiveAs part of our research on Swedish school principals, we examined the occurrence and co-occurrence of conflicts and five negative acts (i.e. harassment, sexual harassment, threats of violence or physical harm, physical violence, bullying), their attributed sources, and their associations with self-rated health, workability, and general life satisfaction among 2670 principals.ResultsDuring
Hexavalent chromium (Cr(VI)) can induce oxidative stress, genomic instability, and epigenetic modifications. In occupational settings, Cr(VI)-exposed workers may also be exposed to other toxicants, such as elements besides Cr, and per- and polyfluoroalkyl substances (PFAS). However, research on the extent of these co-exposures and their combined effects remains limited. The objective of this study
Event cameras and LiDARs provide complementary yet distinct data: respectively, asynchronous detections of changes in lighting versus sparse but accurate depth information at a fixed rate. To this day, few works have explored the combination of these two modalities. In this article, we propose a novel neural-network-based method for fusing event and LiDAR data in order to estimate dense depth maps
In this work, we study the problem of estimating the in-ear sound field using microphone measurements at nearby positions. Typically, the sound field is first interpolated to the position of the head under free-field assumptions, followed by filtering through pre-measured head-related transfer functions (HRTFs). While properties of free-field interpolation methods have been well studied with respe
Electric power is the foundation of modern society, yet Europe is currently facing an energy crisis, increasing interest in power generation, energy infrastructure, and grid resilience. However, power plant data are complex and multidimensional, making it difficult to gain an overview or understanding. Visualization methods can help to reduce cognitive load and facilitate exploration of such data.
Explicit solutions to optimal control problems are rarely obtainable. Of particular interest are the explicit solutions derived for minimax problems, providing a frame work to address adversarial conditions and uncertainty. This work considers a multi-disturbance minimax Linear Regulator (LR) framework for positive linear time-invariant systems in continuous time, which, analogous to the Linear-Qu
Att förstå komplexa och skiftande institutionella ramar har länge varit en viktig fråga inom socialvetenskaplig forskning. Nu mer än någonsin tidigare aktualiseras detta av den nya socialtjänstlagen som betonar tidiga socialarbetarinsatser som sker på frivillig basis och med förtroende som grund, medan andra delar av socialt arbete präglas av kontroll och disciplin. I ”Take Away-studien” har vi fö
SVAR JÄMSTÄLLDHETSENKÄT JÄMFÖRELSE 2007 OCH 2009, GEOLOGISKA INSTITUTIONEN 2009 och 2007 Svarsfrekvens: 53 (60 ) st anställda - 20 (23 ) kvinnor och 33 (37 ) män Kursivt är frågor eller frågealternativ från 2007 ALLA SVAR I PROCENT 1. Den praktiska/organisatoriska arbetsmiljön 1a. Har du ett stressigt arbete? Ja Delvis Nej Ej svarat ALLA 07 Q 16 84 0 0 ALLA 07 M 9 73 15 3 ALLA 09 Q 40 55 5 ALLA 09
https://www.geologi.lu.se/sites/geologi.lu.se/files/jolk_enkatsvar_redovisning_jamforelse_07_och_09.pdf - 2026-07-02
QMOD 2016: Final Program 22nd September 2016, Thursday 9:30- 11:00 Room 1: Plenary Session 2 ”The success of «Made in Italy»: global challenges and constraints” Marco Frey, Professor Sustainability Management Research Group, Sant’Anna School, Pisa, Italy Gianluca Brozzetti, CEO CEO Buccellati Group (Luxury Sector), Milan Giorgio Marini, Manager Operational Excellence Division of ABOCA SpA 11:00- 1
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/19th_qmod_program_2016_1.pdf - 2026-07-02
Background: Case-control studies suggested a moderate, but consistent, association of hepatitis C virus (HCV) infection with lymphoid tissue malignancies, especially non-Hodgkin lymphoma (NHL). More limited data suggested that hepatitis B virus (HBV) infection might also be associated with NHL. However, prospective studies on the topic are few. Methods: A nested case-control study was conducted in
Purpose: To investigate the use of different modes of transport and long-term changes among stroke survivors with cognitive functional limitations (CFLs), and to study differences among sub-groups (decreased/ceased vs. unchanged and increased public transport use) regarding physical functional limitations (PFLs), CFLs, depression, and social activity outside home. Method: Survey of 79 individuals
Background: The influence of daily life exposure on the gastrointestinal tract is not fully understood. This study aimed to examine associations between functional gastrointestinal symptoms and sociodemographic status and lifestyle habits in the general population. Methods: The Malmö Offspring Study (MOS) included 2,648 participants from the general population who had answered a questionnaire abou
Efficient screening of ligands interacting with G-protein-coupled receptors is central for modern drug development. Here, we describe an optimized reporter vector primarily intended for use in reporter cell lines expressing such receptors. The construct consists of a synthetic enhancer containing 9x TRE (12-O-tetradecanoylphorbol-13-acetate-responsive elements) fused to a minimal CMV (cytomegalovi
