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This paper attempts to address the failings of a predominant paradigm in IS research and practice that emphasises technological determinism. This paradigm makes use of a false belief in the power of rationality in organizational decision-making, and a mythology in which organizational actors can be viewed as passive ‘users’ of technology. We wish to create a discussion of the nature and role of pr
This article explores the use of sustainability criteria for biomass as a tool to promote and safeguard sustainability of this product. Much attention is paid to the issues that sustainability criteria for biomass should consider. Among them the priority for food supply and food security, the emission reduction of green house gases (GHG) through the whole production chain, the preservation of area
In order to make the hydrogen economy fully sustainable, renewable resources have to be employed for its production. Simulation models, developed with Aspen Plus to calculate mass and energy balances, will be used to integrate the process steps necessary to produce pure hydrogen from biomass in a 2-stage fermentation process. The main challenge is the reduction of water and heat demand connected t
Nontypeable Haemophilus influenzae (NTHi) commonly causes local disease in the upper and lower respiratory tract and has recently been shown to interfere with both the classical and alternative pathways of complement activation. The terminal pathway of the complement system is regulated by vitronectin that is a component of both plasma and the extracellular matrix. In this study, we identify prote
Ensuring energy security and mitigating climate change are key energy policy priorities. The recent Intergovernmental Panel on Climate Change Working Group III report emphasized that climate policies can deliver energy security as a co-benefit, in large part through reducing energy imports. Here, using five state-of-the-art global energy-economy models and eight long-term scenarios, we show that w
The theme of this essay is to examine how prophet stories are presented for children. The specific aim is to analyze the narrative structure of two texts presenting the story of Adam. The study uses two Arabic children texts presenting the Story of Prophet Adam (pbuh). The study starts with presenting some theories and their typological frame of narratology and some of their narratological tools,
Satellite cell proliferation is an essential step in proper skeletal muscle development and muscle regeneration. However, the mechanisms regulating satellite cell proliferation are relatively unknown compared to the knowledge associated with the differentiation of satellite cells. Moreover, it is still unclear whether overload muscle fiber hypertrophy is dependent on satellite cell proliferation.
Den Tekniska divisionen vid MAX IV stödjer organisationen att möjliggöra teknik och vetenskap på världsledande nivå likväl som operativ excellens i utförandet av aktiviteter och processer. Den Tekniska divisionen har fokus på utveckling av system, teknologi och lösningar och består av det Centrala Projektkontoret samt grupperna Teknik I, Teknik II, Elektronik, IT Infrastruktur, Mjukvara samt VeteThe Technical Division at MAX IV supports the organisation to enable world leading technology and science as well as operational excellence. The Technical Division focus on development of systems, technology and solutions and consists of the Central Project Office and the groups Engineering I, Engineering II, Electronics, IT Infrastructure, Software and Scientific Data.
We consider the graph k-colouring problem encoded as a set of polynomial equations in the standard way. We prove that there are bounded-degree graphs that do not have legal k-colourings but for which the polynomial calculus proof system defined in [Clegg et al. 1996, Alekhnovich et al. 2002] requires linear degree, and hence exponential size, to establish this fact. This implies a linear degree lo
Tropomyosin-related kinase A (TrkA) receptor mediates the effects exerted by nerve growth factor on several subpopulations of neuronal cells. Ligand binding to TrkA induces receptor autophosphorylation on several tyrosine residues and the activation of signaling cascades. In this study, we describe a new site relevant for TrkA regulation, the tyrosine 701 (Y701), which is important for receptor tr
Dysregulation of autophagy has been observed in obesity and type 2 diabetes. Salt-inducible kinase 2 (SIK2), a member of the AMPK-related kinase family, is downregulated in adipocytes from obese or insulin resistant individuals and was previously demonstrated to regulate autophagy in cancer and normal cell lines. The aim of this study was thus to investigate a potential role of SIK2 in the regulat
Transforming growth factor-beta (TGF-beta) is involved in vascular formation through activin receptor-like kinase (ALK)1 and ALK5. ALK5, which is expressed ubiquitously, phosphorylates Smad2 and Smad3, whereas endothelial cell (EC)-specific ALK1 activates Smad1 and Smad5. Because ALK5 kinase activity is required for ALK1 to transduce TGF-beta signaling via Smad1/5 in ECs, ALK5 knockout (KO) mice w
Activation of extracellular-signal-regulated kinase-1/2 (Erkl/2) by phosphorylation to p-Erkl/2, and proliferation of Schwann cells were investigated in the rat sciatic nerve by immunohistochemistry. Axotomy in vivo and culturing of nerve segments in vitro resulted in a rapid (30 min) increase of p-Erkl/2 in Schwann cells with peaks at 2 and 24 h. Proliferation measured by bromodeoxy uridine incor
Neuroblastoma and ganglioneuroma are neuroblastic tumors originating from the developing sympathetic peripheral nervous system. Ganglioneuromas are usually benign, while neuroblastomas have a variable prognosis and include very aggressive tumors. Examples exist of neuroblastomas regressing to ganglioneuromas and ganglioneuromas progressing to neuroblastomas. Little is known of the molecular differ
Denna uppsats syftar till att undersöka samspelet mellan principen om jämbördig suveränitet stater emellan och möjligheterna för rättslig prövning och verkställighet av mänskliga rättigheter. I synnerhet undersöks rätten till hälsa, såsom den redogörs för i International Covenant on Economic, Social and Cultural Rights. Uppsatsen innehåller en sammanfattning av suveränitetsteorin och dess klassiThis thesis seeks to examine the interplay of the theory of equal sovereignty between states and justiciability of human rights, in particular the right to health, as enshrined in the International Covenant on Economic, Social and Cultural Rights (ICESCR). The essay contains an overview of the theory of sovereignty, divided into its two main paradigms of thought, namely universalism and particula
Avdelningens uppdrag är underhåll, fastighetsskötsel samt leverans av tjänster gentemot såväl externa parter, som fakultetens interna verksamheter. Avdelningen ansvarar även för: besiktning, underhåll och reparationer av instrument och utrustning enligt serviceavtal med brukare. att ta emot felanmälningar och beställningar från verksamheten. verksamheten i receptionerna på BMC och CRC. hj
In this paper a simple analytical method is introduced for calculating the overall thermal conductivity of a twin pipe in district heating network. The method is developed based on calculating the conductive and convective heat transfer around the casing pipe in different perimetral sections. Temperature inside the supply and return pipes and also over the heating pipe is measured on different poi
