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The genetic contributions to early onset heart failure (HF) are incompletely understood. Genetic testing in advanced HF patients undergoing heart transplantation (HTx) may yield clinical benefits, but data is limited. We performed deep-coverage whole genome sequencing (WGS) in 102 Swedish HTx recipients. Gene lists were compiled through a systematic literature review. Variants were prioritized for
This book provides a highly accessible and user-friendly overview of the essential concepts and terms related to the current global endeavour to implement the Sustainable Development Goals.With the first decade of the 15-year timespan of the 2030 Agenda now past, the SDGs show limited progress and several goals are even regressing. It is imperative that SDG implementation is accelerated until 2030
Since the introduction of the RUT tax deduction in 2007, the market for private domestic care services has grown rapidly in Sweden. Today, deductions can be made for cleaning and gardening, as well as for care services such as going for walks, providing companionship, assisting with dressing, and helping with personal hygiene. One main group that make use of the tax deduction are elderly over the
The objective of this thesis is to comprehensively demonstrate the existing extent, and the nature of the Ius Cogens Human Rights Obligations of Transnational Companies and their enforcement in the international law. The existing international human rights law is mainly state-centric as it creates obligations primarily upon States to promote human rights. Apart from that one can outline an affluen
Förenta Nationernas Ekonomiska Kommission för Europas Konvention om tillgång till information, allmänhetens deltagande i beslutsprocesser och tillgång till rättslig prövning i miljöfrågor (Århuskonventionen) anses vara det essentiella rättsligt bindande instrumentet för skyddet av allmänhetens miljörelaterade rättigheter. Konventionen bygger på uppfattningen att processuella rättigheter i samband The United Nation Economic Commission for Europe’s Convention on access to information, public participation in decision-making, access to justice in environmental matters (hereafter the Aarhus Convention) is considered to be the main legally binding instrument protecting the public’s environmental rights. It is based on the idea that procedural rights relating to environmental matters should cont
This paper investigates the feasibility of OCA for ASEAN after the implementation of ASEAN Economic Community Blueprint in 2008. Dynamic Conditional Correlation (DCC) model with and without a structural break are used to identify whether the policy implemented facilitates the region to move closer to a single currency area. Industrial production index growth rate and change in short-term interest
The treatment of sewage sludge is often a neglected part of wastewater treatment operation in developing countries. It is generally perceived as an additional operational cost and its importance for an adequate sanitation system is not fully recognized. Therefore, the production of sewage sludge represents a risk of human health and the environment due to the potential of spreading pathogens. In M
The starting point and reoccurring theme of this work is the accommodation of the effective judicial protection of individuals in the European Union system of review of validity of its acts. The discussion of this issue was intense during the decade before the adoption of the Lisbon Treaty due to the Court of Justice’s judgments in the two famous cases Unión de Pequeños Agricultores and Jégo-Quéré
A recurring theme in debates on European Union politics is the lack of enthusiasm and involvement of European citizens in the decision-making and legislative procedures, which may appear complex and impermeable. While some scholars deny the existence of a democratic deficit, others fear that continued failure to bridge the gap between the political elite and the constituents will lead to an ever-d
The importance ascribed to knowledge externalities for understanding the spatial organization of industries (i.e. clustering) is increasingly being exposed to critical theoretical and empirical scrutiny. This research has not yet spilled over into studies of creative industries. This paper is concerned with reducing this omission by making an empirically based assessment of the importance of respe
OBJECTIVE: to determine the impact of Factor V-Leiden on the patency of peripheral vascular reconstructions. DESIGN: prospective, open and consecutive study. METHODS: a total of 775 patients, who were electively admitted between 1995 and 1997 to the vascular ward unit, were prospectively analysed for frequency of Factor V-Leiden mutation and patency of reconstruction (one month and one year). The
In this paper a study of a career planning project launched by the Swedish National Tax Board is reported. The project, named Propeller, was initiated in 1998 as a joint endeavour among three agencies: the Swedish National Tax Board, the Regional Stockholm Tax Office and the Enforcement Authority. The intention was to create a common micro labour market in order to encourage employees to become mo
The value of bone mineral density (BMD) measurements to stratify fracture probability can be enhanced in a case-finding strategy that combines BMD measurement with independent clinical risk indicators. Putative risk indicators include age and gender, BMI or weight, prior fracture, the use of corticosteroids, and possibly others. The aim of the present study was to develop a mathematical framework
Förmannaansvar (command responsibility) är en form av straffansvar som utvecklats till största delen under 1900-talet och ger möjlighet att åtala militära befälhavare och andra överordnade för krigsbrott samt brott mot mänskligheten genom att bevisa tre rekvisit. Inledningsvis måste befälhavaren ha effektiv kontroll över den underordnade som begått brottet. Vidare krävs att befälhavaren innehar enCommand responsibility is a mode of criminal responsibility that developed mostly during the 20th century and provides the opportunity to charge military commanders and other superiors for war crimes and crimes against humanity committed by their subordinates by proving three criteria. To begin with, the commander must have exercised effective control over the subordinate, moreover the commander m
The article presents and analyses the editorial ideals and practices of the Enlightenment press with regard to their participatory elements. The decline of these ideals and practices, during the era of the establishment of the modern press in the 1820s, 1830s and 1840s, is discussed with regard to its advocates’ self-legitimating ambitions. These professional efforts were carried out in various wa
The overall aim of the chapter is to reflect a classroom project on creative learning processes by four “dialogues” between researcher and teacher perspectives on a sequence of themes that lead up to the morale of the tale; Computers and learning, Creativity and education, Creative teaching and Creative learning.
This study is motivated by the need to know the characteristics of the learning processes in tongue-computer interaction and to obtain a useful insight to a better design of the tongue-computer interface for computer text input. Tongue-typing can be a good alternative to hand input methods for physically disabled individuals or tasks where hand-typing is not possible. In order to evaluate the proc
