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Introduction: The hepatic cytochrome P450 system includes the polymorphic CYP2D6 gene. CYP2D6 ultra rapid metabolizers (UMs) were 10-fold more common in suicide victims than in the general population in a previous study. The aim of this study was to investigate if the occurrence of the CYP2D6 UM genotype differs between subjects with and without previous suicide attempt in patients treated for dep

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In order to understand and manipulate biological function at the molecular level, access to high-resolution structures of biological macromolecules is essential, as structure is intimately linked to function. The two main experimental techniques that can achieve atomic, or near-atomic, resolution are crystallography and electron microscopy. Unfortunately, the experimental data alone is typically n

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The complexity of modern healthcare continues to evolve, emphasizing the need for comprehensive collaboration among professionals from diverse backgrounds, patients, and their families to integrate care. Multidisciplinary team meetings (MDTMs) have emerged as an opportunity to advance interprofessional collaborative practice. However, despite their growing prevalence in clinical and educational co

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How may changes in musicians’ experience of time influence their impressions of hav- ing conscious intentions during musical activity? In this essay I will present and discuss an autoethnographic account of how an exceptionally heightened awareness of time during musical improvisation may be connected to a heightened awareness of one’s own mental activity, particularly of speedy internal deliberatHow may changes in musicians’ experience of time influence their impressions of having conscious intentions during musical activity? In this essay I will present and discuss an autoethnographic account of how an exceptionally heightened awareness of time during musical improvisation may be connected to a heightened awareness of one’s own mental activity, particularly of speedy internal deliberativ

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Speech signal decoding relies on both cognitive performance and the ability to perceive the acoustic signal in sufficient detail. In everyday communication, natural speech is often rapid, spatially and spectrally complex, and accompanied by noise. The brain generates predictions to cope with the complex nature of the auditory signal in speech perception. Anticipatory coarticulation is a natural pa

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(conference presentation at the "Svensk gnosis genom tiderna"/"Swedish Gnosis through the ages" conference, Stockholm, April 2025)

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BACKGROUND: The predictive value of atrial conduction abnormalities, reflected by P-wave indices (PWI), and their association with biomarkers signaling fibrosis for the development of atrial fibrillation (AF) in patients with heart failure (HF) remains underexplored.OBJECTIVE: We aim to investigate the associations between PWI, fibrosis biomarkers, and the risk of incident AF in patients with HF.M

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The South-to-North Water Diversion Project (SNWDP), the world’s largest water transfer initiative, is designed to address northern China’s acute water scarcity by diverting approximately 45 km3 of water annually from the south through three major routes, with completion targeted for 2050. This review demonstrates that the SNWDP has already improved water security for over 150 million people, stabi

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The invention pertains to a process for preparing a random co- poly(hydroxycarbonate) comprising reacting a 6-membered di-cyclic carbonate with a polyol, or a monohydric alcohol, via a ring-opening polymerization (ROP) by catalytic control for carbonate unit formation, in the presence of a catalyst, through a ring- opening polymerization reaction. Also, the invention pertains to a random co- poly(

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The invention pertains to a process for preparing a random co-poly(urethane-carbonate) comprising reacting a 6-membered di-cyclic carbonate with a polyamine via a ring- opening polymerization (ROP) by catalytic control for carbonate unit formation, in the presence of a catalyst, through a ring-opening polymerization reaction. Also, the invention pertains to a random co-poly(urethane-carbonate) bei

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FLT3 is a critical prognostic marker in acute myeloid leukemia (AML) due to its high frequency of mutation. Primary mutations in FLT3 include point mutations or deletions in the tyrosine kinase domain (TKD) and internal tandem duplications (ITD) in the juxtamembrane (JM) region. These mutations lead to ligand-independent activation, disrupting the JM region and kinase domain interaction, resulting

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Homelessness has increased significantly in Sweden since the early 1990s. A national survey of homelessness in 2023 showed that 27,383 people were in one of the four homelessness situations that are used in Sweden, namely 1) Acute homelessness, 2) Institutional and supported housing, 3) Long-term housing organised by the municipality and 4) Short-term accommodation arranged on one’s own. These homHomelessness has increased significantly in Sweden since the early 1990s. A national surveyof homelessness in 2023 showed that 27,383 people were in one of the four homelessnesssituations that are recognised in Sweden, namely: (a) acute homelessness; (b) institutional orsupported housing; (c) long-term housing organised by a municipality; and (d) short-termaccommodation arranged by people themselv

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FN:s oberoende kommission har slagit fast att ett folkmord pågår i Gaza. Trots det vägrar Lunds universitetsledning att ompröva sina samarbeten med israeliska universitet och företag med kopplingar till vapenindustrin.Lunds universitet måste nu ta ansvar och avbryta dessa samarbeten – eller erkänna att man väljer att blunda för brott mot mänskligheten. Det skriver 16 forskare från Lunds universite

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Polyoxometalates (POMs) and their instrinsic discrete nature has enabled them to support a wide range of research spanning solution-speciation chemistry, biological/medical assays, catalytic processes and fundamental crystallography. The structure-property relationship of POMs are a consequence of their constiuent metal atoms, which inevitably are formed under specific regimes - for simplicity, ac