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Molecularly imprinted monodisperse microspheres for competitive radioassay

In the present study, molecularly imprinted affinity sorbents against theophylline and 17β-estradiol are synthesised via precipitation polymerisation, a synthetic method that yields monodisperse, spherical polymer particles in the micronscale range, quickly, cleanly and in good yield. The specific binding sites that are created during the imprinting process are analysed via radioligand binding ana

Perlecan Heparan Sulfate Proteoglycan Is a Critical Determinant of Angiogenesis in Response to Mouse Hind-Limb Ischemia

Background: Perlecan is a heparan sulfate proteoglycan (HSPG) constituent of the extracellular matrix with roles in cell growth, differentiation, and angiogenesis. The role of the HS side chains in regulating invivo angiogenesis after hind-limb ischemia is unknown. Methods: Heparan sulfate (HS)-deficient perlecan (Hspg2 δ3/δ3 ) mice (n= 35), containing normal perlecan core protein but deficient i

Are Perinatal Events Risk Factors for Childhood Thyroid Autoimmunity?

Background: Environmental and genetic factors possibly trigger thyroid autoimmunity. Studies on perinatal risk factors for childhood thyroid autoimmunity are sparse.Objectives: The aim was to investigate if perinatal factors, family history of autoimmune diseases, and HLA-DQ genotypes contribute to thyroid autoimmunity in the Diabetes Prediction in Skåne (DiPiS) study.Methods: Samples from 1,874 t

Ablation mechanisms of nanosecond and picosecond laser scribing for metal halide perovskite module interconnection – An experimental and numerical analysis

Laser-based fabrication of metal-halide perovskite mini-modules has recently been demonstrated using nanosecond (ns) laser pulses. However, it still suffers from high-resistance contacts due to remaining PbI2 residues at the bottom of the absorber-opening P2 scribe line. Therefore, in this study, we investigate the effect of shorter picosecond (ps) laser pulses, and thus lower heat input, on the c

Decentralized ventilation unit for window frame integration

Swedish National Board of Housing, Building and Planning reported in "Energi i bebyggelsen"that 80 % of the detached houses in Sweden were under-ventilated, and had a flow of 0.23 l/(s·m2) on average instead of, by the code, required 0,35 l/(s·m2). Well known concerns here are lacking indoor environmental quality and a risk of moisture problems in certain rooms and in the envelope. The naturally v

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It has long been known that the story of Barlaam and Ioasaph - or Barlaam and Iosafat as it was known in the Latin West - despite being a Christian legend is really a Buddha life that has gone through several transformations. From a probably Sanskrit original, the story passed through a Manichaean version, was turned into an Ismaelitic Muslim legend; from there it passed into a Georgian Christian

Information Thermodynamics and Fluctuations in Quantum Dots

In small systems with large fluctuations, the classical description of thermodynamics is no longer sufficient which has led to the development of stochastic thermodynamics. One important result from stochastic thermodynamics is that with measurement and feedback it is possible to use those fluctuations to extract work from a single heat bath coupled to the system. This is thanks to the connection

CT is unreliable in locoregional staging of early colon cancer : A nationwide registry-based study

BACKGROUND AND OBJECTIVE: The option to treat early colon cancer (CC) with local resection, as well as trials investigating neoadjuvant treatment, has increased the importance of identifying early-stage disease in the workup. Most CC patients are T- and N-staged preoperatively with CT, although its reliability in staging early CC remains elusive. The aim of this study was to investigate CT-staging

Space Weather Physics: Dynamic Neural Network Studies of Solar Wind-Magnetosphere Coupling

This thesis presents studies of solar wind-magnetosphere coupling using dynamic neural networks in combination with statistically correlative analysis. The primary contribution of the thesis is dynamic neural network models that can be implemented for near real-time predictions of geomagnetic storms from the solar wind alone. With acceptable accuracy, the prediction time has been extended up to 5

Processability Theory applied to written and spoken L2 Swedish

This study investigates grammatical development in foreign and second language learners of Swedish. The hypothesis is that the hierarchy of processability predicted by Processability Theory (Pienemann 1998) guides both written and spoken learner production. The data was collected from 9 foreign language learners studying Swedish at Melbourne University and 11 second language learners studying Swed

Analysis of the Software supply chain from a logistics control point of view

In industries like high-tech and automotive, increasingly more of the product value delivered to the customer is based on a combination of hardware (HW) and software (SW), where SW handles much of the differentiation of capacity and features. The “logistics process” of SW, especially when it merges with HW along the process, has so far been little studied but a problem noticed is the difficulties

Anorthoscopic vision: Designing and Sensing the Future

Anorthoscopic vision: Designing and Sensing the Future Tom O’Dell As a means of thinking about the future and issues of uncertainty, I would like to take my point of departure in a project I completed a few years ago (O’Dell 2013) concerning plans to develop a huge particle sciences facility in Lund, called the European Spallation Source (ESS). I was the only ethnologist working with a team of 1

Laminar Burning Velocity and Development of a Chemical Kinetic Model for Small Oxygenated Fuels

Popular Abstract in Swedish Sedan 1900-talets början har jordens medeltemperatur ökat med ca 0.9 grader, vilket bland annat resulterat i mer extremt väder, varmare världshav och att världens isar smälter med översvämningar av kustregioner som följd. Det är numera accepterat att denna temperaturökning med stor sannolikhet beror på människans utsläpp av växthusgaser, ex koldioxid (CO2). KoncentratioThe thesis work was performed with the aim of increasing knowledge and understanding of the combustion of oxygenated fuels and intermediates. This was accomplished in two steps: experimental measurements of the laminar burning velocity to expand current databases and development of a reaction mechanism. In the first part of the project, the laminar burning velocity of oxygenated fuels and interme

Evaluation of the effects of DBS in the caudal Zona incerta on brain activity during a working memory task in patients with essential tremor

Essential tremor (ET) is characterized by bilateral upper limb postural and/or kinetic tremor, but also cognitive deficits. Tremor in ET, as well as aspects of cognitive deficits associated with ET, have been suggested to be linked to dysfunction in the cerebello-thalamo-cerebral circuit. In ET patients with disabling and medically intractable motor symptoms, Deep Brain Stimulation (DBS) is effect

‘Mortgaged lives’ : the biopolitics of debt and housing financialisation

The paper expands the conceptual framework within which we examine mortgage debt by reconceptualising mortgages as a biotechnology: a technology of power over life that forges an intimate relationship between global financial markets, everyday life and human labour. Taking seriously the materiality of mortgage contracts as a means of forging new embodied practices of financialisation, we urge for

All-cause mortality and death by aortic dissection in women with Turner syndrome : A national clinical cohort study

Background: Turner syndrome (TS) is a complex genetic disorder with raised mortality. Our objective was to investigate mortality and causes of death in TS. Methods: A matched retrospective observational study of women with TS recruited from the Turner centers in Sweden were conducted. A total of 472 women with TS, ≥16 years old with a cytogenetically verified diagnosis and 2357 controls, matched f

Bayesian learning with Gaussian processes for low-dimensional representations of time-dependent nonlinear systems

This work presents a data-driven method for learning low-dimensional time-dependent physics-based surrogate models whose predictions are endowed with uncertainty estimates. We use the operator inference approach to model reduction that poses the problem of learning low-dimensional model terms as a regression of state space data and corresponding time derivatives by minimizing the residual of reduc

Direct device integration of single 1D nanoparticle assemblies; a magnetization reversal and magnetotransport study

Nanochains (NCs) made up of a one-dimensional arrangement of magnetic anoparticles (NPs) exhibit anisotropic properties with potential for various applications. Herein, using a novel self-assembly method we directly integrate single NCs onto desired substrates including devices. We present a nanoscopic analysis of magnetization reversal in 1D linear NP arrays by combining x-ray microscopy, magnet