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Mild to Moderate Cognitive Impairment Does Not Affect the Ability to Self-Report Important Symptoms in Patients With Cancer : A Prospective Longitudinal Multinational Study (EPCCS)

Context: Patients with advanced cancer commonly suffer from both distressing symptoms and cognitive impairment, but the effect of cognitive impairment on the reliability and validity of symptom self-report is unknown. Objectives: To evaluate the reliability and validity of symptom self-report in cancer outpatients with and without mild to moderate cognitive impairment. Methods: This was an analysi

Robust PID control of propofol anaesthesia: uncertainty limits performance, not PID structure

Background and objective: New proposals to improve the regulation of hypnosis in anaesthesia based on the development of advanced control structures emerge continuously. However, a fair study to analyse the real benefits of these structures compared to simpler clinically validated PID-based solutions has not been presented so far. The main objective of this work is to analyse the performance limit

Opportunities for Seaweed Biorefinery

This introductory chapter provides an overview of seaweed biorefinery opportunities, providing basis for multiple value chains, contributing to nutrition and health of a growing global population, to local job generation and development, to ecosystem services, and not the least to climate change mitigation and adaptation. A unique and rich diversity of the seaweed components provides the basis for

Patients' aged ≥65 years dispositions during ambulance assignments, including factors associated with non-conveyance to hospital : A longitudinal and comparative study

Objectives Patients ≥65 years old represent 30%-50% of all ambulance assignments (AAs), and the knowledge of which care level they are disposed to is limited and diverging. The aim of this study was therefore to describe and compare characteristics of patients' aged ≥65 years dispositions during AA, including determining changes over time and factors associated with non-conveyance to hospitals. De

Mapping Bedrock lithology in urban environment via large scale time domain induced polarization tomography

The present work is an example of a Direct-Current resistivity and time-domain Induced Polarization (DCIP) survey, carried out in an urban environment. The main goal of the survey is to map a weak zone in the bedrock, through which a tunnel will be constructed. Geophysical measurements in urban environments can be very complicated due to the restrictions of available space and the high levels of n

Search for flavour-changing neutral tqH interactions with H → γγ in pp collisions at (Formula presented.) TeV using the ATLAS detector

A search for flavour-changing neutral interactions involving the top quark, the Higgs boson and an up-type quark q (q = c, u) is presented. The proton-proton collision data set used, with an integrated luminosity of 139 fb−1, was collected at (Formula presented.) TeV by the ATLAS experiment at the Large Hadron Collider. Both the decay process t → qH in tt¯ production and the production process pp

Long-term Mortality and Hospital Readmissions Among Survivors of Sepsis in Sweden : A Population-Based Cohort Study

Background. Survivors of sepsis may experience long-term risk of increased morbidity and mortality, but estimations of cause-specific effects beyond 1 year after a sepsis episode are lacking. Method. This nationwide population-based cohort study linked data from national registers to compare patients aged ≥18 years in Sweden admitted to an intensive care unit from 2008 to 2019 with severe communit

Effectiveness and Safety of the ESC-TROP (European Society of Cardiology 0h/1h Troponin Rule-Out Protocol) Trial

BACKGROUND: European guidelines recommend the use of a 0h/1h hs-cTn (high-sensitivity cardiac troponin) protocol in patients with acute chest pain. We aimed to determine the performance of this protocol in routine care when supplemented with patient history and ECG and a recommendation to refrain from noninvasive testing in low-risk patients.METHODS AND RESULTS: This was a pre- and postimplementat

Towards prevention of self-objectification in young female athletes on social media : instagram posting patterns of female elite athletes in aesthetic and non-aesthetic individual sports

Background Elite athletes are role models for young sportspersons regarding social media use. Self-objectification, including self-sexualizing, contributes to body dissatisfaction and body shame, especially in young females. For efficient prevention of self-objectification, knowledge is needed about elite athletes’ self-presentation on social media.Objective To compare social media postings indica

Early Life Factors and Polycystic Ovary Syndrome in a Swedish Birth Cohort

Polycystic ovary syndrome (PCOS) is a medical condition with important consequences for women’s well-being and reproductive outcomes. Although the etiology of PCOS is not fully understood, there is increasing evidence of both genetic and environmental determinants, including development in early life. We studied a population of 977,637 singleton women born in in Sweden between 1973 and 1995, follo

Value of preclinical systematic reviews and meta-analyses in pediatric research

Similar to systematic reviews (SRs) in clinical fields, preclinical SRs address a specific research area, furnishing information on current knowledge, possible gaps, and potential methodological flaws of study design, conduct, and report. One of the main goals of preclinical SRs is to identify aspiring treatment strategies and evaluate if currently available data is solid enough to translate to cl

Perceptual bias contextualized in visually ambiguous stimuli

The visual appearance of an object is a function of stimulus properties as well as perceptual biases imposed by the observer. The context-specific trade-off between both can be measured accurately in a perceptual judgment task, involving grouping by proximity in ambiguous dot lattices. Such grouping depends lawfully on a stimulus parameter of the dot lattices known as their aspect ratio (AR), whos

Numerical and experimental investigation on the residual stresses generated by scanning induction hardening

Induction hardening is widely used in the industry as a surface heat treatment that improves the surface and the subsurface hardness of components greatly. The hardened case, which usually is a few mm, highly impacts the surface and structural integrity of the component. In this work, we simulate the scanning induction hardening process by means of finite element modeling. The computed hardness, m

Burden of Morbidity after Allogeneic Blood or Marrow Transplantation for Inborn Errors of Metabolism : A BMT Survivor Study Report

Survival after blood or marrow transplantation (BMT) for inborn errors of metabolism (IEM) is excellent; however, the burden of morbidity in long-term survivors of BMT for IEM remains understudied. This study examined the risk of chronic health conditions (CHC) in ≥2-year survivors of allogeneic BMT for IEM performed between 1974 and 2014 using the BMT Survivor Study. In this retrospective cohort

Long-term Survival and Cardiovascular Morbidity after Elective Open Aortic Aneurysm Repair in Patients with and without Type 2 Diabetes : A Nationwide Propensity-Adjusted Analysis

Background: Epidemiological data indicate decreased risk for development and growth of abdominal aortic aneurysm (AAA)among patients with diabetes mellitus (DM), but DM also goes with increased cardiovascular (CV)morbidity and mortality. We evaluated the effects of DM on mortality and CV morbidity after elective open AAA repair. Methods: This is a nationwide observational cohort study of patients

A sedimentary model for transverse inland dunes in central Scandinavia

The largest dune fields in Sweden and Norway are small in international comparison but still form distinct parts of this previously glaciated landscape. The dunes formed c.10.5-9 ka ago, shortly after the last deglaciation, when winds close to the ice sheet were strong and vegetation was largely absent [1-4]. Since then they have been more or less stable and today they are covered by forest. Most

Optimizing high-order harmonic generation in strong fields

We present high-order harmonic generation results obtained with different laser systems a 1 ps 1053 nm Nd-glass laser a 2 ps 616 nm synchronously pumped dye laser a 36 ps 1064 nm mode-locked Nd-YAG laser and the second harmonics (308 nm and 532 nm) of the latter two systems. We investigate the influence of the laser pulse width the excitation wavelength (from the near infrared to the ultraviolet)

Usefulness of a clinical risk score to predict the response to cardiac resynchronization therapy

Background: Almost 1/3 of heart failure patients fail to respond to cardiac resynchronization therapy (CRT). A simple clinical score to predict who these patients are at the moment of referral or at time of implant may be of importance for early optimization of their management. Methods: Observational study. A risk score was derived from factors associated to CRT response. The derivation cohort wa

In situ observations of tin deposition into nanoporous anodic aluminium oxide

Populärvetenskaplig sammanfattningAluminium används för en stor mängd produkter, allt från hus och i fordon till såvardagliga produkter som aluminiumburkar. Det breda användningsområdet beror på aluminiumets höga hållfasthet, lätta vikt och dess goda korrosionsmotståndighet. Korrosionsmotståndet beror på att när aluminium exponeras för luft bildas ett aluminiumoxidskikt på ytan, vilket skyddar aluAbstractIn this thesis, the electrochemical deposition process of Sn into ordered nanoporous anodic aluminium oxide (NP-AAO) have been studied. The deposition process was studied in situ using the X-ray techniques: X-ray diffraction (XRD), Grazing incidence Transmission Small-Angle X-ray Scattering (GTSAXS), X-ray Fluorescence (XRF) and X-ray Absorption Near Edge Structure (XANES) and ex situ usin