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Different designs of the SX-700 plane grating monochromator have been investigated for the undulator beamline (51) by using analytical considerations and carrying out ray tracing calculations. The most important modifications of the original design are those where the ellipsoidal focusing mirror has been replaced by a plane elliptical or by a spherical mirror. A significant advantage of the spheri
Scientific performance is often evaluated by bibliometric indicators such as publication counts or citations. But this may neglect other relevant outputs from research units. An optimal evaluation would measure each dimension separately, but this would be costly. Luckily, cluster analyses show that units which specialise in other types of research activities (such as knowledge transfer or educatio
Body temperature (Tb) is a valuable parameter when assessing the physiological state of animals, but its widespread measurement is often constrained by methods that are invasive or require frequent recapture of animals. Alternatives based on automated remote sensing of peripheral Tb show promise, but little is known about their strengths and limitations. We measured peripheral Tb in great tits Par
Boosting innate immunity represents an important therapeutic alternative to antibiotics. However, the molecular selectivity of this approach is a major concern because innate immune responses often cause collateral tissue damage. We identify the transcription factor interferon regulatory factor 7 (IRF-7), a heterodimer partner of IRF-3, as a target for non-antibiotics-based therapy of bacterial in
The most complete and realistic physiological data are derived from direct measurements during human experiments; however, they present some limitations such as ethical concerns, time and cost burden. Thermophysiological models are able to predict human thermal response in a wide range of environmental conditions, but their use is limited due to lack of validation. The aim of this work was to vali
The cytosolic Ca2+-binding S100A9 and S100A8 proteins form heterodimers that are primarily expressed in human neutrophils and monocytes. We have recently shown that S100A9 binds to TLR4 in vitro and induces TLR4-dependent NF-κB activation and a pro-inflammatory cytokine response in monocytes. In the present report we have further investigated the S100A9-mediated stimulation of TLR4 in monocytes. U
Objective Overproduction of cell-free fetal hemoglobin (HbF) in the preeclamptic placenta has been recently implicated as a new etiological factor of preeclampsia. In this study, maternal serum levels of HbF and the endogenous hemoglobin/heme scavenging systems were evaluated as predictive biomarkers for preeclampsia in combination with uterine artery Doppler ultrasound. Study design Case-control
To increase the market share of hybrid vehicles within the automotive industry, it is necessary to minimize the cost increase related to the hybridization. In this context a methodology to estimate the cost of the electrical machine and transmission is developed. Insights on the selection of a cost effective electrical machine topology are provided and the benefits and disadvantages of different d
A real-time digital signal processor (DSP) based implementation of a subband beamforming algorithm and its evaluation for dual microphone speech enhancement is presented. The algorithm, a calibrated constrained beamformer, is described theoretically and a real-time structure is proposed, including an efficient approach for multichannel data transformation. Measurements show that the battery driven
This paper presents a method for blind beamforming with application in realtime speech extraction in a non-stationary environment. The blind beamforming is carried out using an online kurtosis maximization approach where the optimization is based on Newton's method. The main novelty of the paper lies in the formulation of the subband kurtosis approximation, where a locally quadratic criterion is s
The introduction of smart phones has redefined the usage of mobile phones in the communications world. Smart phones are now equipped with various sophisticated features such as Wi-Fi, Global Positioning System (GPS) navigation capability, high-resolution camera, touch screen, and broadband access which helps the mobile phone users to stay connected and updated. Many of these features are primarily
Increasingly the material research deals with is cast as data. This is an ambiguous concept, which describes the matter of research in all stages of the research process. From having been seen as a stepping-stone on the way to producing the scientific results, increasingly data is itself positioned as the result. At the same time demands for data preservation and open data are often motivated with
