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A respiratory virus emitted in an aerosol particle will experience a tough journey with many obstacles before finding a new host where it can cause an infection (Fig. 1). By every second, its chances to replicate decrease due to removal by building ventilation, deposition on surfaces, or loss in infectivity. Thus, the transport of infectious viruses from the exhaled breath of one person to the inh
Ten per cent of patients with colorectal cancer will develop peritoneal metastases. These metastases are known to have a lesser response to systemic chemotherapy than liver- and lung metastases. Randomized studies have shown that adding cytoreductive surgery and heated intraperitoneal chemotherapy (HIPEC) to this treatment gives a better chance of survival. Recently, a randomized study failed to s
Path integration is a computational strategy that allows an animal to maintain an internal estimate of its position relative to a point of origin. Many species use path integration to navigate back to specific locations, typically their homes, after lengthy and convoluted excursions. Hymenopteran insects are impressive path integrators, directly returning to their hives after hundreds of meters of
Simulations and comparisons on the influence of internal coolant crossflow of a novel film cooling hole design, called “sister holes”, and a baseline cylindrical hole were performed with an established turbulence model. The results show that sister holes can provide better film cooling performance than the baseline case at three blowing ratios, and as the blowing ratio increases the sister holes s
The auto-ignition caused by oblique shocks was investigated experimentally in a supersonic flow regime, with the incoming flow at a Mach number of 2.5. The transient characteristics of the auto-ignition caused by shock evolvements were recorded with a schlieren photography system, and the initial flame kernel generation and subsequent propagation were recorded using a high-speed camera. The fuel m
The development of new modes at x-ray free electron lasers has inspired novel methods for studying fluctuations at different energies and timescales. For closely spaced x-ray pulses that can be varied on ultrafast time scales, we have constructed a pair of advanced instruments to conduct studies targeting quantum materials. We first describe a prototype instrument built to test the proof-of-princi
Fetal growth restriction (FGR) in human pregnancy is associated with perinatal mortality, short- and long-term morbidities. No prenatal therapy is currently established despite decades of research. We aimed to review interventions in animal models for prenatal FGR treatment, and to seek the next steps for an effective clinical therapy. We registered our protocol and searched MEDLINE, Embase, and T
OBJECTIVE: Trigger finger (TF) is a hand disorder causing the fingers to painfully lock in flexion. Diabetes is a known risk factor; however, whether strict glycemic control effectively lowers risk of TF is unknown. Our aim was to examine whether high HbA1c was associated with increased risk of TF among individuals with diabetes.RESEARCH DESIGN AND METHODS: The Swedish National Diabetes Register (
Novel rotating-cylinder sliding vane rotary compressors (RC-SVRCs) are promising machines in energy conversion systems due to extremely low friction. However, three-dimensional visual investigations on geometrical optimizations of RC-SVRCs are highly limited. Besides, most flow mechanisms and leakage flow affected by geometric structures have not been fully revealed yet. Therefore, the sliding van
Heat exchanger network synthesis is an essential optimisation tool for Process Integration, particularly in energy-intensive industries. Proper design or retrofit of heat exchanger network can enable energy conservation, efficiency improvement, and process debottlenecking. Many earlier pieces of research have focused on the impact of the network structure and process features such as network topol
Jet impingement cooling was investigated on a flat heating surface placed in a flow channel, including single jet cooling, in-line double jet cooling, and combined crossflow and jet cooling; cross-flow cooling was a baseline for comparison. In addition, the in-line double jet cooling was explored with various jet distances. Local Nusselt number distribution was experimentally achieved by the liqui
The demand for fast and energy efficient (opto-)electronic applications needs high mobility semiconductor materials, such as InAs with a very high electron mobility and GaSb with a very high hole mobility. Beyond the material itself, also an innovative device geometry is needed, for example, the gate-all-around geometry that provides higher efficiency and electrostatic control for computational un
In this work, a discontinuous airfoil fin printed circuit heat exchanger (PCHE) was used as a recuperator in a micro gas turbine system. The effects of the airfoil fin geometry parameters (arc height, maximum arc height position, and airfoil thickness) and the airfoil fin arrangements (horizontal and vertical spacings) on the PCHE channel’s thermo-hydraulic performance were extensively examined by
We investigate the impact of impurity configuration on electronic and optical properties of YVO4 through application of plane-wave DFT. Since this crystal is a common host material for optical devices and it has been widely used as a phosphor and a laser host material, it is important to identify a correlation between impurity location and the intrinsic properties of the material. To further impro
Efficient thermal management of lithium battery modules has become a thorny problem in the development of autonomous underwater vehicles (AUVs), especially under high current discharge. In this article, the fin/phase change material (PCM) composite structure was proposed for AUV's battery thermal management with consideration of natural convection. The temperature behavior of the battery and the m
Background: Norm values for patient reported outcomes, that is knowledge about how the general population of women rate their breast-related satisfaction and quality of life, are necessary to interpret the meaning of scores. The aims of this study were to create Swedish normative values for the BREAST-Q reduction/mastopexy module and to describe what healthy women are most satisfied/dissatisfied w
Objective: To investigate the effects of fever therapy compared with no fever therapy in a wide population of febrile adults. Design: Systematic review with meta-analyses and trial sequential analyses of randomised clinical trials. Data sources: CENTRAL, BIOSIS, CINAHL, MEDLINE, Embase, LILACS, Scopus, and Web of Science Core Collection, searched from their inception to 2 July 2021. Eligibility cr
This research investigated convective heat transfer and hydraulic resistance of smooth and corrugated double-tube heat exchangers at various flow rates from 60 L/h to 200 L/h. The inner tube with a thread structure is designed with three pitches, i.e., 4 mm, 6 mm and 8 mm. Nanofluids are used as tube-side fluids to analyze the enhancement of heat transfer on the inner tube side. Results show that
