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The 13C mobility and cross-β-sheet structure of lipid-protein co-assemblies formed by incubating ganglioside GM3-containing model membranes with the amyloid protein α-synuclein were investigated by solid-state NMR and wide-angle X-ray scattering (WAXS) at varying lipid-to-protein ratios and membrane compositions at body temperature. The POPCGM3 model membrane was characterized by PT ssNMR and X-ra
Immune checkpoint inhibitors have drastically improved the prognosis for several cancer patients, but still the exact underlying mechanism behind cancer immune escape and the role of individual immune cell populations remains poorly understood. Thus, further insights into the level of immune cell infiltration in cancers, their functional role, level of activation and maturity are warranted in orde
Samhället präglas av digital utveckling som anses medföra stora fördelar. Inom det juridiska området tar primärt EU digitaliseringen i anspråk vid sin verksamhet. Sverige har högt uppsatta digitaliseringsmål men är inte lika lyckade som EU på att lagtekniskt följa med i denna utveckling. Med utgångspunkt i digitaliseringen av samhället utreds i den här uppsatsen huruvida det är möjligt att, utifråSociety is characterized by digital development, which is considered to bring great benefits. In the legal field it is primarily the EU that uses means towards digitalization in its operations. Sweden’s goals for digitalization are high but the country has not been as successful as the EU in staying current with the development judicially. With the digitization of society as its basis, this paper
In times of climate change, companies face extreme pressure from external stakeholders to engage in environmental sustainability activities. Especially companies of industries that significantly contribute to the global carbon emissions are expected to change their behaviour. There, the road freight transportation business is known for its particularly heavy impact. Being forced to adapt to change
Recently, we reported that DNA associated with inverse hexagonal (H(II)) lyotropic liquid crystal phases of the lipid 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) was actively transcribed by T7 RNA polymerase. (1) Our findings suggested that key components of the transcription process, probably the T7 RNA polymerase and the DNA, remained associated with the monolithic H(II) phase throughou
The purpose of this study was to evaluate the effect of prolonged heat processing (180 min at 50-80 degrees C) on the functional and theological properties of pectin, derived from olive mill wastewater (OMW). It was shown that a low temperature blanching of OMW at 60 degrees C, activates endogenous pectin methyl esterase and promotes demethylation, despite the high concentration of phenols. Activa
Photo-Fenton oxidation was used for treatment of synthetic textile wastewater as stand alone treatment, as pre-treatment before aerobic biological treatment and as post-treatment after anaerobic biological treatment. The processes were compared with regards to decolorization, chemical oxygen demand (COD) reduction and chemical consumption. When applying photo-Fenton alone for treatment of Remazol
Aims Vegetation stimulates, in general, soil mineral weathering. It has been hypothesized that plant-associated microorganisms, especially ectomycorrhizal fungi play a major role in this process. We studied apatite dissolution in a vegetation gradient in southern Norway to test the role of ectomycorrhizal vegetation on mineral weathering. Methods A natural occurring lead contamination, probably pr
Fractions rich in indigestible carbohydrates, such as fructan and arabinoxylan, are obtained as by-products when ethanol, starch, and gluten are produced from wheat flour. Today, these fractions are used as animal feed. However, these components may have positive physiological effects in humans. In this study, the content of indigestible carbohydrates in distillers' grains and process streams from
Popular Abstract in English Parkinson’s disease is the second common neurological disease whose major clinical symptom is progressive impairment in the ability to control the body movements. The symptoms are mainly caused by the gradual loss of dopamine producing neurons in a very specific part of the brain, termed substantia nigra. Although there exist some drug and surgical therapies, those mosParkinson’s disease is a progressive neurodegenerative disorder. Since the motor manifestations of the disease is associated with the loss of dopaminergic (DAergic) neurons in the substantia nigra pars compacta, cell replacement therapy is a promising approach for treatment. Although several different cell types have been used in clinical trials, with the recent findings of somatic cell nuclear tr
Examensarbetet redogör för hur ett rekonstruktionsförfarande går till enligt gällande rätt och redogör även till viss del för den kritik som har riktats mot förfarandet och hur lagstiftaren har gått tillväga för att möta denna kritik. Bland annat anses förfarandet vara långsamt och dyrt. Det har vidare angetts att det saknas en enhetlig reglering för konkursförfarandet och rekonstruktionsförfarandThis thesis sets out to describe how a business reorganization procedure works according to existing Swedish law. This thesis also aims to describe the proposed changes and why the changes have been proposed. The current law has been criticized of being slow and inefficient, and also that it is too expensive to reorganize smaller businesses. There is no convenient way to change direction from busi
MKB Fastighets AB (MKB) is a municipally owned company in Malmö Stad with a well-established position on the housing market, meaning that MKB owns 22 238 rental apartments and 1000 commercial spaces which are 33% of the tenancy market in Malmö. Their business concept is to provide rental apartments to a wide range of people with different socio-economic conditions. According to Swedish law, the co
The (re)appearance of different Far-Right parties in Italy during the last decades brought me to the decision to write my Master's thesis about this topic. Due to the fact that in this country, together with a long tradition of support for Far-Right ideologies, more than one tipology of Far-Right party exists, an interesting scenario is open for the analysis. I will study the cases of Lega Nor
This paper takes a point of departure in the municipality of Copenhagen (two administrations herein) and their participation in Eurocities. The main question is what kind of processes of Europeanization that takes place in the two administrations. Furthermore, it will be discussed what kind of approach they are taking to European cooperation and how their perception and reflection on the matter is
The aim of this study is to explore the fundaments of all psychoanalytic interpretative models, and especially the psychoanalytic literary criticism. Drawing from different fields as affect theory, neuropsychology and Lacan's structural psychoanalysis, strong evidence is found that language in itself contains and transmits affects. The empiric study indicates that different readers of a text,
2008 ändrades den svenska sjukförsäkringsprocessen till ett nytt system, rehabiliteringskedjan. Rehabiliteringskedjan är i lag fastslagna tidpunkter i sjukskrivningsprocessen, där den sjukskrivnes arbetsförmåga ska prövas mot olika bedömningsgrunder. Den första är mot sina ordinarie arbetsuppgifter, den andra mot vad ens arbetsgivare kan erbjuda och den tredje är mot ett arbete som anses vara normIn 2008 the system for the assessment process within the Swedish sickness benefit was changed, into the rehabilitation chain. Within the rehabilitation chain, there are different stages of assessing the individual’s capacity for work. The different stages of assessments are enforced by law. The first assessment examines if the individual has the work ability to work with his or her regular task as
I en intervju med publicisten Ken Tyler så beskrev den amerikanska efterkrigskonstnären och abstraktionisten Helen Frankenthaler uppfinnarskapet som en regellös aktivitet: “Så föds konsten, på det sättet sker genombrott. Bryt mot reglerna eller ignorera dem. Det är vad uppfinnarskap handlar om.” Jämfört med juridikens precisa och noggranna metodik så framstår uppfinnandets skapande metod något anThe U.S. painter Helen Frankenthaler, a behemoth of post-war American abstractionist painting, once described the act of inventing as an activity without rules. ”This is how art is born, how breakthroughs happen. Go against the rules or ignore the rules. That is what invention is about”, she is quoted saying in a 1994 interview with legendary publisher Ken Tyler. In contrast with the precise and
De senaste åren har den svenska juridiken satts under press då gängkriminaliteten i landet blomstrar. Inom det svenska rättssystemet är det särskilt bevisvärderingen som har varit en aspekt som föranlett debatter om huruvida svenska domstolar gör fullgoda värderingar. Av särskilt intresse inom bevisvärderingen är de alternativför- klaringar som presenteras i rätten och därigenom inverkar på domsluIn recent years, Swedish jurisprudence has been subject to ominous pressure parallel to the flourishing of as gang crime. Within the Swedish legal system, the evaluation of evidence has been a particular aspect that has sparked debates on whether Swedish courts make adequate assessments in such cases. Particularly, the evaluation of al- ternative explanations presented in court is of specific inte
During travels, people want to be able to move fast and smooth from point A to point B. Thereby, many people can relate to the struggles which occur when carrying several belongings simultaneously. This master’s thesis was performed in collaboration with Thule Sweden AB and the purpose was to develop a design concept which would make it easier to travel with a wheeled luggage in combination with
