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INTRODUCTION.: The most common immunosuppressive treatment in de novo renal transplantation is a triple regimen that includes tacrolimus, mycophenolate mofetil (MMF) and corticosteroids, and that may also include antibody induction. Whether nephrotoxicity is an issue with tacrolimus at the currently used dosages remains an open question. METHODS.: We pooled data from three large, randomized, de no

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Introduction: Intraperitoneal adhesions are common after abdominal surgery and may lead to serious clinical complications. Previous studies have investigated the possible effects of the polypeptides poly-L-lysine (αPL) and poly-L-glutamate (PG) forming a polymer complex that prohibits local peritoneal adhesions after surgery. The aim of this study was to examine whether the normal process of perit

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Interactions between ionic surfactants (sodium dodecyl sulfate and dodecyltrimethylammonium chloride) and nonionic polymers ((hydroxyethyl)cellulose, ethyl(hydroxyethyl)cellulose and their hydrophobically modified analogous) have been studied by means of rheology, pulsed field gradient nuclear magnetic resonance (PFG NMR), time-resolved fluorescence quenching (TRFQ), dynamic light scattering (DLS)

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Within the next 30 years, two thirds of the human population will live in a city. This growing urban population requires a major shift in the way we produce and distribute food, since conventional agriculture practices are responsible for climate change, biodiversity losses, pollution of waterways, soil degradation, etc. Urban and peri-urban agriculture and forestry represent one of the strategies

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Aim: The aim of this study was to investigate how otherwise healthy older adults with self-assessed voice problems relate to their voice and voice changes. Method: Focus groups were conducted at an activity center to identify how older adults reflect on their own voice and the aging voice in general. The interviews were audio recorded and transcribed. The analysis was done using thematic content a

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Objective: Huntington's disease (HD) is an inherited neurodegenerative disease with motor, cognitive and psychiatric symptoms. Non-motor symptoms like depression and altered social cognition are proposed to be caused by dysfunction of the hypothalamus. We measured the hypothalamic neuropeptide oxytocin in plasma and cerebrospinal fluid (CSF) in a cohort of HD gene expansion carriers (HDGECs), comp

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The passage of the Americans with Disabilities Act of 1990 (ADA)signified a new era of mobility for elderly and disabled passengers.There have been many debates about fixed-route versus door-todoordemand-responsive services. While the United States hasbeen discussing the issue, Sweden has been experimenting since1983 with a concept called service routes. Madison Metro (inWiscon_sin) is very close

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BACKGROUND: Asthma is characterised by an aggravated immune response to respiratory viral infections. This phenomenon is a clinically well-recognised driver of acute exacerbations, but how different phenotypes of asthma respond immunologically to viruses is unclear. OBJECTIVES: To describe the association between different phenotypes and severity of asthma and bronchial epithelial immune responses

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Salinity tolerance-associated phenotypes of 35 EMS mutagenized wheat lines originating from BARI Gom-25 were compared. Vegetative growth was measured using non-destructive image-based phenotyping. Five different NaCl concentrations (0 to 160 mM) were applied to plants 19 days after planting (DAP 19), and plants were imaged daily until DAP 38. Plant growth, water use, leaf Na+, K+ and Cl− content,

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A rapid decarbonisation of the energy sector is key for mitigating climate change and in this transformation a transition to renewable heating is essential. To date, most attention in both research and policy on decarbonisation has been on electricity and transport systems, with less interest in the heating system. Half of the EU’s final energy consumption is made up by the heating and cooling sec

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Following the impressive development of bulk lead-based perovskite photovoltaics, the “perovskite fever” did not spare nanochemistry. In just a few years, colloidal cesium lead halide perovskite nanocrystals have conquered researchers worldwide with their easy synthesis and color-pure photoluminescence. These nanomaterials promise cheap solution-processed lasers, scintillators, and light-emi

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Mitt avhandlingsarbete är ett teoretiskt utforskande av den mellanmänskliga förståelsens tvetydiga roll i praktiskt socialt arbete. Avhandlingen är en sammanläggningsavhandling vilket betyder att den är uppbyggd av flera delstudier och en introducerande tillika sammanfattande kappa. I mina fyra delstudier om ämnena empati, stigmatisering och kamratstöd undersöker jag olika aspekter av mellanmänsklThis thesis aims to explore how phenomenological philosophy may contribute to the conception of interpersonal understanding in the context of social work practice. The thesis consists of an extended introduction and four original papers, investigating modalities of interpersonal understanding in relation to three different subjects, namely empathy, stigmatization, and peer-support. The thesis sets

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BackgroundWomen are at a greater risk of a major adverse cardiovascular event (MACE) after percutaneous coronary intervention than men. A history of preterm delivery is a female-specific risk factor for coronary artery disease, but its relevance in the treatment of coronary artery disease is unknown.ObjectivesThe purpose of this study was to analyze the association between a history of preterm del

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Background: Sepsis is common in the intensive care unit (ICU). Two of the ICU’s most widely used mortality prediction models are the Simplified Acute Physiology Score 3 (SAPS-3) and the Sequential Organ Failure Assessment (SOFA) score. We aimed to assess the mortality prediction performance of SAPS-3 and SOFA upon ICU admission for sepsis and find a simpler mortality prediction model for these pat

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Background: Sexual dysfunction is common following a cancer diagnosis in young adulthood (18–39 years) and problems related to sex life are ranked among the core concerns in this age group. Yet, few studies have investigated to what extent adults younger than 40, receive information from healthcare providers about the potential impact of cancer and its treatment on their sex life. Methods: A popul

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Forward-only algorithms offer a promising memory-efficient alternative to Backpropagation (BP) for on-device training. However, state-of-the-art forward-only algorithms, e.g., Forward-Forward (FF), still require a substantial amount of memory during the training process, often exceeding the limits of mobile edge and Internet of Things (IoT) devices. At the same time, existing memory-optimization t

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This thesis discusses the use of standards in land-use planning risk management regulations. Based on exploring the domains of standards and standardisation, risk science, and risk management regulations, the research contributes significant empirical evidence capturing the perspectives of risk managementpractitioners in terms of the strengths, the weaknesses and the effects of using standards in

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Background: Serially interconnected microfluidic devices enable advanced applications such as multi-step chemical processing and multi-organ-on-chip systems. However, managing these systems presents challenges due to interdependent fluid dynamics in their connecting channels, where even minor disturbances can propagate throughout the network, affecting overall system performance. Methods: This stu

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AIM: To explore nursing students' experiences of what they had learned and gained through participating in simulation-based communication training anchored in person-centred values.BACKGROUND: Person-centredness is a core component of nurses' work and an important part of it is person-centred communication. To promote patients' wellbeing and comfort, nursing students must become prepared during th