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Purpose: Here, we describe an integrated bioinformatics, functional analysis, and translational pathology approach to identify novel miRNAs involved in breast cancer progression. Experimental Design: Coinertia analysis (CIA) was used to combine a database of predicted miRNA target sites and gene expression data. Using two independent breast cancer cohorts, CIA was combined with correspondence anal

Direct electron transfer (DET) reactions of recombinant tobacco peroxidase (rTOP), namely direct electroreduction of Compound I/ Compound II and heme Fe3+/2+ conversion, were studied on gold electrodes. rTOP of wild type, non-glycosylated, was produced using, an Escherichia coli expression system. At pH 5.0, the redox potential for direct electrochemical transformation of the Fe3+/2+ of the peroxi

Urinary tract infections (UTIs) are clustered in certain individuals but the molecular basis of disease susceptibility is not known. A single gene was shown to control the susceptibility to acute pyelonephritis and renal scarring in mice. The IL-8 receptor homologue (mIL-8Rh) controls neutrophil function during acute infection and the mIL-8Rh deletion causes tissue damage through neutrophil entrap

Background: TCF7L2 is a central transcription factor in the canonical wingless-type MMTV integration site (WNT) signaling pathway, and genetic variants in TCF7L2 have been found to interact with dietary fiber intake on type 2 diabetes risk. Here, we investigate whether other type 2 diabetes genes could be involved in the WNT signaling pathway and whether variants in such genes might interact with

Structural compromise of the tumor suppressor gene, PTEN occurs in 10% of melanoma specimens and loss of PTEN expression through DNA methylation of the PTEN promoter region has also been reported in a number of other malignancies. However, the role of PTEN promoter methylation in melanoma is not well understood. We thus sought to elucidate the prevalence of PTEN promoter methylation in melanoma sp

Several studies have reported associations of hypertension with cancer, but not all results were conclusive. We examined the association of systolic (SBP) and diastolic (DBP) blood pressure with the development of incident cancer at all anatomical sites in the European Prospective Investigation into Cancer and Nutrition (EPIC). Hazard ratios (HRs) (95% confidence intervals) were estimated using mu

Hip geometry is an important predictor of fracture. We performed a meta-analysis of GWAS studies in adults to identify genetic variants that are associated with proximal femur geometry phenotypes. We analyzed four phenotypes: (i) femoral neck length; (ii) neck-shaft angle; (iii) femoral neck width, and (iv) femoral neck section modulus, estimated from DXA scans using algorithms of hip structure a

Background Chronic inflammation plays a critical role in the pathogenesis of the 2 major types of gastric cancer. Several foods, nutrients, and nonnutrient food components seem to be involved in the regulation of chronic inflammation. Objective We assessed the association between the inflammatory potential of the diet and the risk of gastric carcinoma, overall and for the 2 major subsites: cardia

Tundra regions are projected to warm rapidly during the coming decades. The tundra biome holds the largest terrestrial carbon pool, largely contained in frozen permafrost soils. With warming, these permafrost soils may thaw and become available for microbial decomposition, potentially providing a positive feedback to global warming. Warming may directly stimulate microbial metabolism but may also

Purpose: Tasquinimod, a novel oral therapy targeting the tumor microenvironment, significantly improved progression-free survival (PFS) in a randomized, placebo-controlled phase II trial in men with metastatic castration-resistant prostate cancer (mCRPC). This phase III study was conducted to confirm the phase II results and to detect an overall survival (OS) benefit. Patients and Methods: Men wit

Globalt Dynamiskt Engagemang Afrika 2024 1GDE AFRIKA 2024 GDE Afrika GLOBALT DYNAMISKT ENGAGEMANG | 2024 2GDE AFRIKA 2024 GDE Afrika Globalt engagemang är en självklar och nödvändig del i Lunds univer- sitets arbete för att kunna fortsätta utvecklas som ett internationellt ledande universitet som värnar demokrati, mänskliga rättigheter och akademisk frihet. Globalt dynamiskt engagemang (GDE) stärk

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2024-01/Ver%201_GDE%20Afrika%202024_0.pdf - 2026-04-25

Masterutbildning i industridesign: utbildningsplan Masterutbildning i industridesign Programkod: TAIDE Omfattning: 120 högskolepoäng Tillträdesnivå: Avancerad nivå Beslutsfattare: Programledning ID Utbildningsplanens giltighet: 2020/2021 Utbildningsplanen fastställd: 2020-02-18 Förutom utbildningsplanen för denna utbildning gäller även ge- mensamma föreskrifter och information för LTH. 1 Syfte och

https://www.student.lth.se/fileadmin/lth/utbildning/studiehandboken/20_21/MID_Uplan_20-21.pdf - 2026-04-25

Course Application | Centre for Mathematical Sciences Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any perso

https://www.maths.lu.se/english/education/masters-programmes/course-application/ - 2026-04-25

In boreal forest soils, mycelium of mycorrhizal fungi is pivotal for regulating soil carbon (C) cycling and storage. The carbon use efficiency (CUE), a key parameter in C cycling models, can inform on the partitioning of C between microbial biomass, and potential soil storage, and respiration. Here, we test the dependency of mycorrhizal mycelial CUE on stand age and seasonality in managed boreal f

We report on the influence of pH and monovalent/divalent cations on the catalytic current response, internal electron transfer (IET), and structure of fructose dehydrogenase (FDH) by using amperometry, spectrophotometry, and circular dichroism (CD). Amperometric measurements were performed on graphite electrodes, onto which FDH was adsorbed and the effect on the response current to fructose was in

BACKGROUND: The efficacy of corticosteroids for treating acute vestibular neuritis, or acute unilateral vestibulopathy (AUVP), remains controversial.OBJECTIVE: This study aimed to evaluate whether corticosteroids improve vestibular function and reduce symptoms in both acute and chronic phases of AUVP.METHODS: This randomized, placebo-controlled, double-blind trial included patients with AUVP (ages

! ! ! ! ANNUAL REPORT 2016 45 55 59 57 58 58 68 61 71 89 82 124 124 144 0 50 100 150 200 250 2010 2011 2012 2013 2014 2015 2016 Funding over time (MSEK) Basic funding External funding 133 134 142 185 132 139 177 188 200 212 245 296 257 311 0 50 100 150 200 250 300 350 2010 2011 2012 2013 2014 2015 2016 Total number of publications Directly relevant Total publica2ons Current numbers Contributing di

https://www.nano.lu.se/sites/nano.lu.se/files/nanolund_annual_report_2016_lowlowres.pdf - 2026-04-25

BACKGROUND: The relative cardiovascular safety of gonadotropin-releasing hormone (GnRH) antagonists compared with GnRH agonists in men with prostate cancer and known atherosclerotic cardiovascular disease remains controversial. METHODS: In this international, multicenter, prospective, randomized, open-label trial, men with prostate cancer and concomitant atherosclerotic cardiovascular disease were

for ultrasound examination of the heart, a technology which prove to be revolutionary for diagnostics. 1995 BLUETOOTH Sven Mattisson and Jaap Hartsen invented the wire- less technology standard for exchanging data over short distances, thereby opening a whole new world for the electronics sector. The tech- nology was introduced onto the market in 1998 and was called Bluetooth after Viking cheif Ha

https://www.lu.se/sites/www.lu.se/files/lund_university_foundation_newsletter.pdf - 2026-04-25

Kursguide - Course Syllabus Books Anderson, Bridget (2015). Us and Them? The Dangerous Politics of Immigration Control. Oxford: OUP. 224 pages. ISBN: 978-0-198-73761-2 Betts, Alexander (Ed) (2012). Global Migration Governance. Oxford University Press. 368 pages, selected chapters. ISBN: 978-0-199-65380-5 Brettell, Caroline B. & James F. Hollifeld (2015). Migration Theory: Talking Across Discipline

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/sims26_english_litteratur_16010_h16.pdf - 2026-04-25