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Neutral pion transverse momentum spectra were measured in p+C and p+Pb collisions at root s(NN) = 17.4 GeV at midrapidity (2.3 less than or similar to eta(lab)less than or similar to 3.0) over the range 0.7 less than or similar to p(T)less than or similar to 3.5 GeV/c. The spectra are compared to pi(0) spectra measured in Pb+Pb collisions at root s(NN) = 17.3 GeV in the same experiment. For a wide

The suppressors of cytokine signaling ( SOCS) family is thought to act largely as a negative regulator of signaling by cytokines and some growth factors. Surprisingly, the SOCS-6 transgenics had no significant defects in the cytokine signaling and hematopoietic system but displayed significant improvements in glucose metabolism. Insulin stimulation of Akt/protein kinase B was also potentiated. Bio

In neuroblastoma x glioma hybrid cells (NG 108-15) labelled with [32P]-trisodium phosphate, [3H]-inositol and [14C]-arachidonic acid, bradykinin stimulated the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) while it had no effect on the release of [14C]-arachidonic acid (AA). The effect on PIP2 was time- and dose-dependent with a maximal effect on [3H]-inositol- and [32P]-labelled cell

New data on the levels and long-range transport of plutonium in the Arctic Ocean, recorded in the course of two expeditions to this zone in, 1994 and 1996, are discussed in this paper. Specifically, approximately 100 plutonium measurements in surface and sub-surface water sampled at 58 separate stations throughout the Kara, Laptev and East Siberian Seas, as well as along latitudinal transects acro

Waxing and waning ice sheets and changing sea levels have been interpreted from the Quaternary stratigraphic record at Leinstranda, Broggerhalvoya in NW Svalbard. We have identified seven high relative sea-level events, related to glacio-isostatic loading, and separated by at least four glacial events. To establish a chronology for the high sea-level events (interstadials and interglacials) and th

The performance of a turbo code can be severely degraded if no trellis termination is employed. This paper investigates the implications of the choice of trellis termination method for turbo codes, and explains the origin of the performance degradation often experienced without trellis termination. An efficient method to derive the distance spectrum of turbo codes for different trellis termination

The view on reactive oxygen species (ROS) in inflammation is currently shifting from being considered damaging toward having a more complex role in regulating inflammatory reactions. We recently demonstrated a role of ROS in regulation of animal models for the autoimmune disease rheumatoid arthritis. Low levels of ROS production, due to a mutation in the Ncf1 gene coding for the Ncf1 (alias p47pho

The variation in dietary exposure to acrylamide (AA) has been studied through measurement of hemoglobin adduct levels from AA, as a measurement of internal dose, in a sample from the blood bank of the Malmo Diet and Cancer Cohort (n = 28,098). The blood donors are well characterised with regard to their food habits, and 142 individuals were selected to obtain highest possible variation in the addu

Background: Congenital cardiovascular diseases are the most common form of birth defects in humans. A substantial portion of these defects has been associated with inappropriate induction, migration, differentiation and patterning of pluripotent cardiac neural crest stem cells. While TGF-beta superfamily signaling has been strongly implicated in neural crest cell development, the detailed molecula

To mimic the electron donor side of Photosystem II (PSII), a number of supramolecular model complexes have been designed and synthesized. Ruthenium(II) tris-bipyridyl complexes have been used in most cases as photosensitizers, mimicking the function of P-680 in PSII. As electron donors, monomeric and dimeric manganese complexes and tyrosine have been introduced into the supramolecular systems, mod

Popular Abstract in Swedish I takt med att analytiska dimensioneringsmetoder utvecklas ökar även behovet av att kunna bestämma mekaniska egenskaper hos materialen i överbyggnaden och terrassen. Utmattningssprickor orsakade av tung trafik, permanenta deformationer (spårbildning), termisk sprickbildning, ojämnheter, tjäle och reflektionssprickor är några av de dimensioneringskriterier som kan användThe advance of analytic (mechanistic) design methods increases the need for fundamental material properties. Fatigue cracking due to traffic loading, in combination with permanent deformation (rutting), thermal cracking, irregularities, frost heave and reflective cracking are some of the major criteria used when designing an asphalt concrete pavement. The objective of this Ph.D. project is to eva

BACKGROUND: Severe alpha 1-antitrypsin (AAT) deficiency (PiZZ) is associated with an increased risk of lung emphysema, especially in smokers. The aim of this study was to identify risk factors other than smoking for declining lung function. METHODS: Lung function was studied in 225 self-reported never-smoking PiZZ individuals included in the Swedish AAT deficiency register. RESULTS: Lung function

The type of chemical reaction between hapten and carrier protein in the formation of a complete antigen in vivo giving rise to an allergic contact dermatitis (ACD, type IV allergy) is essentially unknown. About 4,000 low-molecular organic compounds are known to have allergenic properties. ,-Unsaturated carbonyl structures are frequently present among these compounds. Haptens giving rise to antibod

Hemopoietic stem cells (HSCs) are maintained at relative quiescence by the balance between the positive and negative regulatory factors that stimulate or inhibit their proliferation. Blocking the action of negative regulatory factors may provide a new approach for inducing HSCs into proliferation. A variety of studies have suggested that TGF-beta negatively regulates cell cycle progression of HSCs