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Research on birds suggests that extreme weather events during development may have long-lasting consequences on form and function. The underlying cellular mechanisms mediating such phenotypic effects are poorly studied. We raised Japanese quail in warm (30°C) or cold (10°C) temperatures from hatching until adulthood and then measured mitochondrial metabolism in intact blood cells at representative
Pain, use of painkillers and alcohol are highly prevalent in the general population. Aims of the study were to describe differences in pain, alcohol consumption and use of painkillers among two 60 year old birth cohorts stratified by gender. Participants were recruited from the Skåne centre of The Swedish National study on Aging and Care, a multicentre, prospective, longitudinal study. The sample
Longer product lifetimes are promoted by the EU's Circular Economy Action Plan, but incentivising longer lifetimes could also result in trade-offs between different environmental impacts for some product categories. LED lamps are still experiencing improvements in efficacy and material design, which raises questions about whether longer lifetimes are desirable from an overall environmental perspec
The decarbonization of the energy-intensive and natural-resourced-based industries is associated with potentially large economic costs. In this paper, I explore how decarbonization may affect the profitability and market value of these industries. I also discuss the possibility of compensating for the investment costs through higher prices and enhanced productivity. I answer these questions using The decarbonization of the energy-intensive and natural-resourced-based industries is associated with potentially large economic costs. In this paper, I explore how decarbonization may affect the profitability and market value of these industries. I also discuss the possibility of compensating for the investment costs through higher prices and enhanced productivity. I answer these questions using
Aims To investigate self-reported cold sensitivity and functional disability after a repaired major nerve trunk injury in the upper extremity. Methods We identified 735 individuals with a major nerve trunk injury in the upper extremity, surgically treated with direct nerve repair or reconstructed with nerve autografts, in the Swedish national quality registry for hand surgery (HAKIR). Patient-repo
Ki67 has potential clinical importance in breast cancer but has yet to see broad acceptance due to inter-laboratory variability. Here we tested an open source and calibrated automated digital image analysis (DIA) platform to: (i) investigate the comparability of Ki67 measurement across corresponding core biopsy and resection specimen cases, and (ii) assess section to section differences in Ki67 sc
OBJECTIVES: To describe clinical characteristics and prognosis related to heart failure (HF) phenotypes in a community-based population by applying a novel algorithm to obtain ejection fractions (EF) from electronic medical records. DESIGN: Retrospective population-based cohort study. SETTING: Data were collected for all patients with HF in Southwest Sweden. The region consists of three acute care
This volume collects eleven studies that investigate different aspects ofthe teaching and learning of Greek in early modern northern Europe (c.1500–1750), from France in the west to Lithuania in the east. They giveimportant insights that advance our understanding of the homogeneitydespite diversity in the complex developments of classical reception, thestudy of Greek, its significance, and the pra
BACKGROUND: Programmed death-ligand 1 (PD-L1) expression on tumor cells is associated with poor prognosis in several malignancies, while partly contradictory and inconclusive results have been presented for colorectal cancer (CRC). This study aimed to evaluate PD-L1 as a prognostic biomarker in CRC by comparing three different antibody clones.METHODS: Patients surgically treated for CRC between Ja
Climate change and drought phenomena impacts have become a growing concern for water resources engineers and policy makers, mainly in arid and semi-arid areas. This study aims to contribute to the development of a decision support tool to prepare water resources managers and planners for climate change adaptation. The Hydrologiska Byråns Vattenbalansavdelning (The Water Balance Department of the H
Statistical emulation allows combining advantageous features of statistical and process-based crop models for understanding the effects of future climate changes on crop yields. We describe here the development of emulators for nine process-based crop models and five crops using output from the Global Gridded Model Intercomparison Project (GGCMI) Phase 2. The GGCMI Phase 2 experiment is designed w
In Sweden, one of SÄPO’s tasks is counterespionage. Once a suspect has been arrested for a crime in chapter 19 of the Criminal Code, crimes against Sweden security, they are the ones conducting the interrogations. These interrogations may be the difference between a guilty spy walking free or not. It’s also a situation where information of the extent of damages to national security as well as clue
I takt med allt mer omfattande globala klimatförändringar växer behovet av förnybara energikällor, såsom solenergi. Det har därför blivit allt vanligare att entreprenörer väljer att ansöka om att få anlägga solcellsparker på jordbruksmark. Förfarandet för en sådan prövning bedöms utifrån 3 kap 4 § miljöbalken och är rättsligt komplicerat. Dessutom ska miljöbalkens övergripande mål om hållbar utvecAs global warming gradually increases, the need for renewable energy sources is growing rapidly. One such energy source is solar energy. It has therefore become more common for entrepreneurs to apply for permission to construct solar parks on larger open areas, such as agricultural land. The assessment is dictated by Chapter 3, Section 4 of the Swedish Environmental Code. However, the procedure fo
Historiskt sett har människor gjort invändningar grundade på tankefrihet, samvetsfrihet och religionsfrihet i förhållande till obligatorisk värnpliktstjänstgöring. Denna samvetsvägran inom militären är en erkänd rätt i nationella, regionala och internationella människorättsinstrument. I den Europeiska konventionen om skydd för de mänskliga rättigheterna och de grundläggande friheterna är denna rätHistorically, objections based on the freedom of thought, conscience and religion have been invoked in relation to compulsory military service. These conscientious objections are protected by national, regional and international human rights instruments. In the European Convention on Human Rights this right is grounded in Article 9 on the freedom of thought, conscience and religion. In Europe, the
