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Background: Summary statistics often hide individual patients' suffering, thereby impeding quality improvement efforts. Objectives: We aimed to show the experience of a population with health care toward the end of life while preserving the experience of the individual. Design: We developed a data display method called per-patient illness trajectory analysis. We tested it using a demonstration coh

Skogen och skogsbruket har idag en stark närvaro i klimatdebatten. Det finns bred enighet om att skogen har stor betydelse för klimatfrågan, men olika syn på vilka dessa klimatnyttor kan vara. Antalet studier inom området är omfattande och relevant styrning utvecklas över tid. Kunskapsläget är dock svåröverblickbart, vilket beror på att olika metoder, antaganden och tidshorisonter använts i olika

This study delves into the landscape of health applications within online markets. These applications, offering health-related functionalities, have become integral to the lives of European citizens. The transformation of healthcare delivery, accelerated by the pace of modern life and accentuated by the COVID-19 pandemic, has elevated health applications from conveniences to essential tools capabl

The wax apple (Syzygium samarangense) is traditionally employed as an antibacterial and immunostimulant drug in traditional medicine. This plant is rich in different flavonoids and tannins. In this study, we isolated two compounds from S. samarangense leaves: Myricitrin and 3,5-di-O-methyl gossypetin. Then, we investigated the mechanisms of action of the two compounds against oxidative stress (ind

Aims: Among patients with myocardial infarction (MI) with preserved left ventricular ejection fraction (LVEF), the REDUCE-AMI trial did not demonstrate a benefit of beta-blocker vs. no beta-blocker treatment on all-cause mortality and recurrent myocardial infarction. The aim of this pre-specified sub-study was to investigate effects of beta-blockers on self-reported symptoms of anxiety and depress

Background: Elevated red cell distribution width (RDW) is associated with increased postoperative mortality, but less is known about kidney outcomes. This study investigated the association between elevated preoperative RDW and postoperative worsening of long-term kidney function and incidence of acute kidney injury. Methods: This retrospective cohort study included patients ≥18 yr undergoing nonc

Despite advancements in multiple myeloma treatment, prognostic variability persists. We investigated the impact of income and education on treatment and survival in a country with publicly funded healthcare. We analysed data from the Swedish Myeloma Registry (2008–2021) linked to national registers. Cox models assessed survival, adjusting for demographics and comorbidities. Treatment patterns were

Japan's January withdrawal of funding from the UN Committee on the Elimination of Discrimination against Women highlights its aversion to addressing gender equality issues at home. Despite externally presenting a commitment to progressive gender norms, a tension between Japan's international image and its domestic reality persists. Japan continues to rank low in major gender equality indexes as re

Background: Ambulatory oxygen therapy is prescribed for patients with chronic lung diseases who experience exertional hypoxemia. However, available devices may not adequately meet user requirements, and their performance characteristics are heterogeneous. Objective: This study aims to identify devices available for delivery of ambulatory oxygen therapy, the technologies that they use to generate o

The use of material extrusion (MEX) has increased rapidly due to the affordability of 3D printers. This has led to a growing demand for improved print quality, high fidelity, strength, or fast print times. In this study, a non-planar approach for better surface quality is investigated. The hardware of a 3-axis MEX printer was developed together with testing new software for non-planar slicing. The

Legal persons have traditionally been understood as entities with legal rights and/or duties. This traditional concept of legal personhood has been challenged during the last decades: In legal practice through the global development in law where previous legal non-persons such as different non-human natural entities, non-human animals, fetuses and artificial intelligences have been ascribed, or be

Abstract in Czech:Studie se zabývá kultem spojeným s osobností Felixe Edmundoviče Dzeržinského (1877–1926), revolucionáře a zakladatele politické policie v Sovětském svazu, a proměnami tohoto kultu v různých etapách dějin SSSR a postsovětského Ruska. Jako vedoucí nejvýznamnější represivní složky, známé pod zkratkou Čeka, stál Dzeržinskij jasně v pozadí zcela konkrétní institucionalizované podoby sThe study discusses the cult associated with the personality of Felix Edmundovich Dzerzhinsky (1877-1926), a revolutionary and the founder of the political police in the Soviet Union, and the changing meanings of this cult in various stages of the history of the Soviet Union and post-Soviet Russia. Thanks to Dzerzhinsky, as the head of the most significant repressive component, Soviet state terror

FN:s mellanstatliga klimatpanel IPCC lyfter i sin femte stora rapport (”Assessment Report 5”, AR5) fram att för att den långsiktiga globala uppvärmningen ska kunna begränsas till mindre än 2 grader, behöver de kumulativa växthusgasutsläppen begränsas till en viss maximal mängd. För att sannolikt uppnå en sådan klimatstabilisering uppgår det totala utsläppsutrymmet, det vill säga mängden kol som få

BACKGROUND: The elapsed time taken to diagnose tumors of the central nervous system in children and adolescents varies widely. The aim of the present study was to investigate such diagnostic time intervals at a national level in Sweden as they correlate with clinical features.METHODS: Data prospectively accumulated over a 4-year period in the Swedish Childhood Cancer Registry from patients aged 0-