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We consider a class of pseudodifferential evolution equations of the form u(t) + (n(u) + Lu)(x) = 0, in which L is a linear smoothing operator and n is at least quadratic near the origin; this class includes in particular the Whitham equation. A family of solitary-wave solutions is found using a constrained minimization principle and concentration-compactness methods for noncoercive functionals. T
The prototypical antimicrobial peptide, melittin, is well-known for its ability to induce pores in zwitterionic model lipid membranes. However, the mechanism by which melittin accomplishes this is not fully understood. We have conducted all-atom and coarse-grained molecular dynamics simulations which suggest that melittin employs a highly cooperative mechanism for the induction of both small and l
As the physical consequences of accidental falls in the elderly are well-researched, the long-term associations between falls and quality of life and related concepts are less known. The aim of this study was to prospectively examine the long-term relations between falls and health-related quality of life (HRQoL) and life satisfaction (LS) over six years in the general elderly population. One thou
We have evaluated the consequences of work organization on musculoskeletal health. Using a postal questionnaire, answered by 1600 female grocery store workers, their main work tasks were identified and four work groups were defined (cashier, picking, and delicatessen work, and a mixed group, who performed a mix of these tasks). The crude odds ratios (ORs) for neck/shoulder complaints were 1.5 (95%
Appropriate regulation of hematopoietic stem cell (HSC) numbers and function is a requisite for life-long blood cell replenishment. Knowledge of factors that regulate HSC activity is derived largely from murine model systems, with serial transplantation often considered a "gold standard" to assess longevity and self-renewal of HSCs. In the literature, we noted inconsistencies in how serial transpl
P>1. Female preferences for particular male ornaments may shift between populations as a consequence of ecological differences that change the reliability and detectability of the ornament, but few studies have examined how ornaments function in different populations. 2. We examined the signalling function of male plumage ornaments in a warbler, the common yellowthroat (Geothlypis trichas), breedi
In Japan, rising costs have impacted the framework of maintaining an efficient and effective healthcare system. Today, urgent implementation of programs to address this need have led to a rebuilding of the entire approach of medical evaluation and clinical care. Recent developments in clinical proteomics based on mass spectrometry (MS) for identifying, sequencing, and quantifying disease-relevant
The functional separation of risk assessment and risk management has long been at the heart of risk analysis structures. Equally long it has been criticized for creating technocratic risk management due to valuations being done in the risk assessment to which the stakeholders do not have access. The criticism has mostly been of an ethical nature. Arguably, in separating risk assessment and risk ma
Next-generation sequencing technologies are making it possible to study the role of rare variants in human disease. Many studies balance statistical power with cost-effectiveness by (a) sampling from phenotypic extremes and (b) utilizing a two-stage design. Two-stage designs include a broad-based discovery phase and selection of a subset of potential causal genes/variants to be further examined in
Despite increasing evidence suggesting the cerebellum works in concert with the cortex and basal ganglia, the nature of the reciprocal interactions between these three brain regions remains unclear. This consensus paper gathers diverse recent views on a variety of important roles played by the cerebellum within the cerebello-basal ganglia-thalamo-cortical system across a range of motor and cogniti
This thesis examines the definition of the term 'self-contained regime', a term firstly used by the International Court of Justice in the Tehran Hostages Case and since then discussed and analyzed by international scholars of international law. The term has been used to label a treaty or set of treaties in international law that set up a system of norms that to some extent exclude the appl
This study stems from an opinion that the current approaches to the repatriation of articles of cultural heritage to their places of origin are inadequate. Attempting to find alternative ways to discuss the matter, I am using idea analysis to investigate if the museums of world culture can be problematised and criticized from a post-colonial perspective – if they can be found to be maintaining a h
Populärvetenskaplig sammanfattning: Huvudsyftet med detta examensarbete har varit att dokumentera samt jämföra skånska sandstenar med västgötska sandstenar avsatta under kambrium (ca 570 - 500 miljoner år). De skånska lagren utgörs till stor del av 120 meter sandsten och de västgötska av ca 35 meter. Sandstenen består huvudsakligen av kvartskorn och kallas därför kvartsitisk sandsten. Under kambThe Lower Cambrian strata of the Caledonian foreland of southern Sweden consist mainly of quartzitic sandstones with thicknesses of approximately 35 meters in Västergötland and 120 meters in Skåne. In the distal, moderately buried western members of the File Haidar Formation of Västergötand porosity and permeability was higher than in the proximal deeply buried units of the Hardeberga Formation of
By utilizing a theoretical framework developed by the Konrad Adenauer Foundation (KAF) we have been able to identify developments in South African press freedom with a special focus on the printed press, between the years of 2003-2007. The purpose of this thesis has been (1) to determine whether there has been an actual decrease in the South African press freedom and (2) to establish a nuanced pic
The main objective of this thesis is to investigate the distribution of hydrological resources over time and space in two sub basins of the Lake Poopó area in Bolivia. This investigation is made in order to evaluate how supply and demand can be balanced and what effect the insufficiency of hydrological resources has on the socio economic situation. The two main problems in the area regarding water
Numerous studies show an association between military pressures and fiscal development, often based on cross-national correlations between wars and fiscal outcomes (e.g., tax ratios). However, investments in fiscal capacity may take time to yield higher tax revenues, obscuring the importance of factors that contributed to those investments. This article shifts attention from fiscal outcomes to the
