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OBJECTIVE-Recent genome-wide association studies have revealed loci associated with glucose and insulin-related traits. We aimed to characterize 19 such loci using detailed measures of insulin processing, secretion, and sensitivity to help elucidate their role in regulation of glucose control, insulin secretion and/or action. RESEARCH DESIGN AND METHODS-We investigated associations of loci identif
Patients with perihilar cholangiocarcinoma and gallbladder cancer extending into the hilum often present with jaundice and a small future liver remnant (FLR). If resectable, preoperative biliary drainage and portal vein embolization (PVE) are indicated. Classically, these measures have been performed sequentially, separated by 4-6 weeks.
Background: In adults, impaired myocardial repolarization and increased risk of arrhythmia are known consequences of open heart surgery. Little is known, however, about post-operative consequences of cardiopulmonary bypass surgery in children. The aim of this study was to assess ventricular repolarization and coronary perfusion after bypass surgery for atrial septal defect (ASD) repair in children
Urbanization and Density in Zanzibar - Recommendations for Sustainable Urban Development from Swahili houses to low-rise multi-storey houses. The rapid urbanization process in Africa is a major challenge for politicians, urban planners and society in general. The archipelago of Zanzibar in Tanzania is in the middle of this process. Traditionally, low and middle income families live in Swahili hous
Power grids worldwide are expanding not only driven by ambitious clean energy, but also because of the rising need for reliable energy. Key components of these power grids are transformers. Transformers are traditionally filled with mineral oil, to serve as a coolant and dielectric insulator. Now globally a rising trend is observed towards the adoption of less flammable, biodegradable transformer
Public service eller radio och TV i allmänhetens tjänst kan betraktas som ett alltmer angeläget ämne att studera mot bakgrund av ett föränderligt medieklimat under intensiv konkurrens. Det bildar en central mediepolitisk fråga att balansera på såväl nationell som överstatlig nivå i förhållande till EU-rätten. I denna uppsats har en nutida förståelse för public service genom TV-sändningarna i allmäPublic service broadcasting can be considered as an increasingly important topic to study in the light of a changing media climate under intense competition. It also represents a central question in media policy to be balanced at a national as well as a supranational level in relation to EU law. In this thesis, an understanding of public service broadcasting with regard to television is based on
Cardiac magnetic resonance (CMR) images are used to investigate the heart for medical and research purposes. By injecting a contrast substance into the patient, myocardial infarctions (heart attacks) can be visualized in CMR image sets consisting of a number of image slices at different levels of the heart. Analysis of these images can detect an infarction, delineate it and estimate its size. This
Populärvetenskaplig sammanfattning Spektroskopi handlar om teoretiska modeller och experiment där man observerar ljus som har växelverkat med materia. Spektroskopiska metoder används inom många olika ämnesområden som exempelvis kemi, fysik och biologi. Ett jordnära exempel på tillämpad spektroskopi är människans öga. Reflekterat ljus från olika föremål samlas in av linsen i ögat, avbildas på näthiIn this thesis a novel spectroscopic method consisting of a combination of frequency domain photon migration (FPDM) and gas in scattering media absorption spectroscopy (GASMAS) is developed, for assessment of the mean optical path length and gas absorption in porous media. The system stability is experimentally investigated and measurements are performed on balsa and pine wood to evaluate the rela
The aim with this master thesis was to investigate if a certain sow feed requires different calibrations in near-infrared analysis, due to if the sow feed have fish oil or AkoFeed as fat source. To investigate this, a basic sow feed mix was prepared and divided in 60 jars with 250 g in each. In 30 of the jars 0 to 15 g fish oil were added and in the other 30 jars 0 to 21 g AkoFeed were added. 2/
There have been reforms in the public sector, from the bureaucratic form of organization to the business community inspired reforms called New Public Management. These reforms have been seen as positive but also negative, especially against downplaying of democratic values. In connection with these changes, even the language being touched. The earlier one named citizen is now called customers. Thi
This conceptual thesis analyses Carlota Pérez vision of a ‘Green Global Golden Age’ that is supposed to reconcile the tension between economic growth and sustainability (Pérez, 2016b). Aiming to address the pressing issue of continued unsustainability, Pérez’ proposed solution is based on the assumption that technological innovation in the field of Information and Communication Technologies (ICT)
Block copolymer lithography is a very promising candidate for nanoscale fabrication and is economically viable. It provides a high resolution, inexpensive, and straightforward approach to nano-size patterning. In this thesis, fundamental concepts and theories of block copolymer lithography are introduced. A well-controlled dynamic solvent vapor annealing chamber is built, and the best annealing co
This study explores the opportunity of advancing climate focused projects within the Swedish energy and climate advising. Inspired by behavioural change and climate communication theory, a pilot project was developed where a climate advising service was tested and reviewed. Further, interviews with responsible climate and energy advisors of other climate focused projects were performed, and togeth
Rockfalls occur around Sweden every year and the country lacks a national risk evaluation and an adequate regulatory framework for construction related to this natural hazard. The aim of this study is to address this problem by mapping areas under possible threat of rockfalls, considering two fundamental aspects: i) identification of the source areas and ii) estimation of the runout zones. The stu
To this day, the question of what factors drive economic development and catching-up remains deeply controversial in growth literature. The concept of social capability provides a useful framework to investigate the relationship of the parallel processes of transformation, inclusion, autonomy and accountability with economic performance. Nevertheless, there are few attempts to quantify social capa
Standardized Care Pathway (SCP) for patients presenting with macroscopic haematuria was introduced in Sweden in 2015. In contrast to neighbouring countries, the Swedish model includes all patients with macroscopic haematuria above the age of 50, notwithstanding obvious causes. The aim of this study was to characterize the patients referred within the SCP and the presence of acute cystitis.All pati
This book challenges the prevailing notion of stability, cohesiveness, and uniformity within Christian communities, inviting readers to view contestation and disagreement as integral to theological reflection and church identity. While the volume focuses predominantly on the Roman Catholic Church as a case study, various chapters broaden the exploration across other Christian and non-Christian tr
Background: Children and adolescents with autism spectrum disorder (ASD) are generally more sedentary and engage less in physical activity (PA) than their peers. Despite increasing evidence of benefits, practical guidance on implementing adapted PA programs in real-world settings remains limited. This study aimed to document iterative adaptations, implementation processes, and participant experi
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