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This work presents a literature review and a questionnaire study with 62 participants aimed at providing recommendations on the design of a set of evacuation systems for road tunnels: 1) Traffic Information Sign (TIS) - message and size of the sign (large or small), colour scheme, and use of pictograms and/or flashing lights, 2) Emergency exit portal layout - colour scheme, 3) Acoustic systems - v
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This study develops the method for solution of inverse heat conduction problem applied to metal cutting. The proposed method operates with a selection procedure involving iterative solutions of heat forward problem. In such formulation, it allows avoiding difficulties associated with ill-posed inverse problems inherent to conventional formulations. Inverse heat problem was transformed into constra
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This contribution presents a modeling and optimization method for multi-column counter-current purification (MCSGP) processes. The model is based on conventional column models and by using the symmetric and cyclic steady state characteristics of the process a single column analog model was developed. The model have been used for dynamic optimization of the MCSGP process. The optimization was based
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Objectives: To describe the process and outcomes of using a new evidence base to develop scientific guidelines that specify the type and minimum dose of exercise necessary to improve fitness and cardiometabolic health in adults with spinal cord injury (SCI). Setting: International. Methods: Using Appraisal of Guidelines, Research and Evaluation (AGREE) II reporting criteria, steps included (a) det
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To evaluate the shared genetic etiology of type 2 diabetes (T2D) and coronary heart disease (CHD), we conducted a genome-wide, multi-ancestry study of genetic variation for both diseases in up to 265,678 subjects for T2D and 260,365 subjects for CHD. We identify 16 previously unreported loci for T2D and 1 locus for CHD, including a new T2D association at a missense variant in HLADRB5 (odds ratio (
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Healthy subjects frequently report minor bleedings that are frequently 'background noise' of normality rather than a true disorder. Nevertheless, unexpected or unusual bleeding may be alarming. Thus, the distinction between normal and pathologic bleeding is critical. Understanding the underlying pathologic mechanism in patients with an excessive bleeding is essential for their counseling and treat
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Rapid warming in the Arctic is transforming northern ecosystems and altering their role in the global carbon cycle. Rising temperatures are driving shifts in vegetation composition, phenology, and ecosystem functioning, including earlier growing seasons and the expansion of shrubs across tundra landscapes. These changes influence surface energy balance, carbon uptake, and climate feedbacks, yet su
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The traditional sheet metal forming process, including cast steel die tool and conventional work materials, is fairly well established and analysed. Developments of new alternative materials make great demands upon new forming processes and manufacturing methods. A general goal for the manufacturing industries is to reduce the weight of metal parts, reduce batch sizes and reduce the lead-time of n
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The legal empowerment approach is a recent attempt to be specific about the role of institutions for the future eradication of poverty. This is a broad concept that includes not only the national formal judicial system in a country, but all formal and informal institutional structures providing the rules of the game of human interaction in any given society. It has invited a lot of debate as to wh
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Soot particles can be formed in hydrocarbon flames as a result of an inefficient combustion process. The particles are near-spherical, and normally a few tens of nanometers in diameter. At later stages in the soot growth process, they form chain-like sparse aggregates. When applying optical diagnostic methods such as combined scattering and extinction measurements in sooting flames, this aggregati
