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To broaden our understanding of bradyarrhythmias and conduction disease, we performed common variant genome-wide association analyses in up to 1.3 million individuals and rare variant burden testing in 460,000 individuals for sinus node dysfunction (SND), distal conduction disease (DCD) and pacemaker (PM) implantation. We identified 13, 31 and 21 common variant loci for SND, DCD and PM, respective
Road traffic pollution is one of the most important factors among other environmental factors that influence the roadside vegetation. The present research examines the impact of motorway flyovers and at-grade roads on air pollution (PM10, SOx, NOx, and air quality index (AQI)) and roadside vegetation in Dehradun by considering the important biochemical parameters such as chlorophyll, ascorbic acid
Aggressive tumours are defined by microenvironmental stress adaptation and metabolic reprogramming. Within this niche, lipid droplet accumulation has emerged as a key strategy to buffer toxic lipids and suppress ferroptosis. Lipid droplet formation can occur via de novo lipogenesis or extracellular lipid-scavenging. However, how tumour cells coordinate these processes remains poorly understood. He
Breast cancer has a profound affect on society. The survival for women in low- and middle-income countries (LMICs) is poor compared to in high-income countries (HICs). The lack of timely diagnosis is one of the main factors contributing to the poor outcomes for women in LMICs. Point-of-care ultrasound (POCUS) combined with a deep learning (DL) classification network could potentially be a suitable
By measuring brain activity, through techniques such as electroencephalography (EEG), it is possible to decode which sound source a person is listening to, called auditory attention decoding (AAD). This can either be done investigating the relation between speech sources and corresponding brain responses over time, or by discrimi-natively estimating directions to which auditory attention is focuse
The proper alignment of requirements engineering and testing (RET) can be key to software's success. Three practices can provide effective RET alignment: using test cases as requirements, harvesting trace links, and reducing distances between requirements engineers and testers. The Web extra https://youtu.be/M65ZKxfxqME is an audio podcast of author Elizabeth Bjarnason reading the the Requirements
Alltsedan det kalla kriget slutade har försvarssektorn, framförallt militär logistik och försvarsmaterielanskaffning, genomgått en genomgripande transformation. Flera faktorer har bidragit till transformationen: förändringar i länders och organisationers försvars- och säkerhetspolitik; reducerade försvarsbudgetar; deltagande i fredsbevarande och fredsframtvingande operationer; erfarenheter från deSince the ending of the Cold War, the defence sector, particularly the areas of military logistics and defence acquisition, has been undergoing a comprehensive transformation. There are several factors that explain this transformation: changes in defence and security policies for nations and organisations; reductions in defence expenditure; participation in Peace Support Operations; Lessons Learne
The semantic formalism reference attribute grammars (RAGs) allows graphs to be superimposed on abstract syntax trees. This paper investigates how RAGs can be used to model visual languages, with a case study of a control language that also has a textual syntax. The language contains blocks on which a total execution order is defined based on connections and layout information. One strength of RAGs
In editors for visual languages it is often useful to provide interactive feedback that depends on the static semantics of the edited program. In this paper we demonstrate how such feedback can be implemented using reference attribute grammars. Because the implementation is declarative, it is easy to modularize compiler and editor computations, reusing the compiler's program model in the editor. F
Popular Abstract in Swedish Små partiklar i form av vätska eller fast material mellan 0.001 till 100 µm i diameter, kan sväva i luften och kallas då aerosolpartiklar. De påverkar direkt på klimatet genom att reflektera solstrålar ut till rymden. Detta gör att vi får ett kallare klimat. Indirekt kan de påverka klimatet genom att verka som kondensationskärnor vid molnbildning. Med detta påverkar de The aim of this work was to study atmospheric aerosols, focusing on the chemical composition, the morphology and the origin of the aerosol in the upper troposphere and lowermost stratosphere. An aerosol sampler was developed for this purpose. A new method for quantitative analysis of the major components of the aerosol, i.e. C, N and O was developed, and methodologies for single-particle analysis
This paper presents a study of the sensor network calibration time-difference-of-arrival (TDOA) measurements. Such calibration arise in several applications such as calibration of (acoustic or ultrasound) microphone arrays, bluetooth arrays, and radio antenna networks. We propose a non-iterative algorithm that apply a three-step stratification process, (i) using a set of rank constraints to determ
JastAddJ is an extensible Java compiler, implemented using reference attribute grammars. It has been shown previously how the language constructs of Java 5, like generics, could be modularly added to the original JastAddJ compiler that supported Java 1.4. In this paper we discuss our experiences from extending Jast- AddJ to support Java 7. In particular, we discuss how the Try-With-Resources state
In this paper, we study the geometry problems of estimating camera pose with unknown focal length using combination of geometric primitives. We consider points, lines and also rich features such as quivers, i.e. points with one or more directions. We formulate the problems as polynomial systems where the constraints for different primitives are handled in a unified way. We develop efficient polyno
Automated object detection is perhaps the most central task of computer vision and arguably the most difficult one. This paper extends previous work on part-based models by using accurate geometric models both in the learning phase and at detection. In the learning phase manual annotations are used to reduce perspective distortion before learning the part-based models. That training is performed o
To identify risk factors for Clostridium difficile infection (CDI) in Danish patients consulting general practice with gastrointestinal symptoms, a prospective matched case-control study was performed; cases (N=259) had positive cultures for toxigenic C. difficile and controls (N=455) negative cultures. Data were analysed by conditional logistic regression. In patients aged 2 years (138 cases), ho
