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In men from the general population, BMI has been associated with a lower sperm DNA fragmentation index (DFI). We wondered whether this could be due to estradiol, which is associated with BMI and reported important for sperm function. Our objective was to investigate the association between estradiol and DFI. In 2008–2010, we recruited 284 young men from the general population to deliver samples of
Nanostraw substrates have great potential for achieving minimally invasive cell transfection. Cells located on the nanostraw substrate are subjected to mild DC electric pulses applied across the nanostraw substrate, which open pores in the cell membrane on top of the nanostraws and drives charged cargo through these pores via electrophoresis. However, with this method, the current may leak throug
Water balance models provide insights into ongoing changes in the water cycle. Among them, monthly water balance models (MWBMs) are especially suitable for large-sample and global assessments, which are important for adaptation to global environmental change. This study evaluates monthly water balances from 14 models across more than 2,000 global catchments, comparing the modelś capacities to repr
This thesis investigates core excited electronic states of molecules in gas phase. In particular, the resonanttransitions of ionised molecules, the site-selectivity surrounding Auger-Meitner decay, and the nuclear dynamicsthat may follow core excitation and ionisation.Background: Fundamental understanding of molecules and ions lay the groundwork for all future applicativescience and production. Fo
This study clarifies when Bayesian analysis provides a practical advantage, particularly in large-area searches, hazardous or inaccessible environments, and low signal-to-noise ratio (SNR) scenarios where direct source approach is not feasible. We present a PyMC-based Bayesian framework for localizing a single unshielded gamma-emitting source and estimating its activity, with the ability to switch
ObjectivesAutoantibodies against tissue transglutaminase (tTG) are serological markers of celiac disease. The aim was to study the applicability of human leukocyte antigen (HLA)-genotyping and tTG autoantibodies in the screening of celiac disease in a longitudinal birth cohort followed to age 15 years.MethodsIncluded were 13,860 HLA-DQ-genotyped children at birth and previously invited to a screen
Consumers evaluate each step of their journey, which influences consumer’s expectations for further experiences and future intentions. Accordingly, past experiences are stored in consumers’ memory but each part of the journey will not be remembered. What drives further behaviours and intentions are the events of the experience that are considered more emotional and atypical, also called peaks. The
Purpose: The purpose of this thesis is to find out what pharmaceutical companies are doing in exploitation and exploration to improve R&D productivity. This research will also investigate the implications of management and control theories in combining exploration and exploitation in the context of pharmaceutical R&D. Methodology: Multiple case study interviews. Theoretical perspective
Using unique Swedish disclosure data from 2007 to 2012, this paper reports three important sets of findings with regard to the relationship between firms’ voluntary disclosure, external financing, and financial status. First, financially strong firms disclose more than weaker ones. Second, firms that obtain new financing (equity or debt) disclose more than firms that do not. Third, the association
Broad systems of meaning permeating a person’s worldview are crucial to personality, because they organize beliefs, values, and attitudes and imbue lives with meaning and direction. Yet they have attracted little research. Humanism and Normativism are arguably the broadest worldview constructs to date, encompassing attitudes about human nature, society, morality, affect, and epistemology. Accor
Legacy streamer data and newer 3D ocean-bottom-cable data are cross-matched and analysed for time-lapse analysis of geomechanical changes due to production in the Valhall Field. The issues relating to time-lapse analysis using two such distinctly different data sets are addressed to provide an optimal cross-matching workflow that includes 3D warping. Additionally an assessment of the differences b
A sense can be given, in qualitative rather than quantitative terms, to the three-part distinction, within the semiotics of culture, of Culture, Non-culture, and Extra-culture, by having recourse to the analysis of pronouns into two binary correlations, personality and subjectivity, originally proposed by Benveniste. The present communication will address two related themes: the possible relations
This paper explores discourses in higher education viewing two pairs of concepts, on the one hand, the concepts of use- vs. exchange value and on the other, the concepts of deep vs. surface learning. Drawing on Yrjö Engeströms’ position of use- vs. exchange value, and his elaboration on the activity system, we assert that any component in an activity system combines two inherent forces which compe
