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Aim: The aim of the present study was to retrospectively investigate the impact of induction chemotherapy on treatment outcome in patients treated with curatively intended radiotherapy for non-small cell lung cancer (NSCLC). Patients and Methods: Patients with a diagnosed NSCLC that have been subjected to curatively intended irradiation (>= 50 Gy) and treated in an oncology department in Sweden du
The most common diseases affecting middle-aged and elderly subjects in industrialized countries are multigenetic and lifestyle related. Several attempts have been made to study interactions between genes and lifestyle factors, but most such studies lack the power to examine interactions between several genes and several lifestyle components. The primary objective of the EpiHealth cohort study is t
The goal of the present paper is to construct a formal explication of the pluralistic ignorance explanation of the bystander effect. The social dynamics leading to inaction is presented, decomposed, and modeled using dynamic epistemic logic augmented with ‘transition rules’ able to characterize agent behavior. Three agent types are defined: First Responders who intervene given belief of accident;
Protein S has an established role in the protein C anticoagulant pathway, where it enhances the factor Va (FVa) and factor VIIIa (FVIIIa) inactivating property of activated protein C (APC). Despite its physiological role and clinical importance, the molecular basis of its action is not fully understood. To clarify the mechanism of the protein S interaction with APC, we have constructed and express
Searches for heavy long-lived charged particles are performed using a data sample of 19.1 fb(-1) from proton-proton collisions at a centre-of-mass energy of root s = 8 TeV collected by the ATLAS detector at the Large Hadron Collider. No excess is observed above the estimated background and limits are placed on the mass of long-lived particles in various supersymmetric models. Long-lived tau slepto
The CP properties of the coupling between the Higgs boson and the top quark are investigated using 139 fb−1 of proton–proton collision data recorded by the ATLAS experiment at the LHC at a centre-of-mass energy of s=13 TeV. The CP structure of the top quark–Higgs boson Yukawa coupling is probed in events with a Higgs boson decaying into a pair of b-quarks and produced in association with either a
We construct a set of Wigner 6j symbols with gluon lines (adjoint representations) in closed form, expressed in terms of similar 6j symbols with quark lines (fundamental representations). Together with these Wigner 6j symbols with quark lines, this gives a set of 6j symbols sufficient for treating QCD color structure for any number of external particles, in or beyond perturbation theory. This faci
The European Union Drinking Water Directive aims to protect human health and promote safe water consumption. The 2020 revision, Article 17 in particular, directed member states to provide public access to information on drinking water. This update was a response to citizen initiatives calling for the active participation of end-users in water services and greater transparency from water utilities.
The evolution of suppressed recombination between sex chromosomes is widely hypothesized to be driven by sexually antagonistic selection (SA), where tighter linkage between the sex-determining gene(s) and nearby SA loci is favored when it couples male-beneficial alleles to the proto-Y chromosome, and female-beneficial alleles to the proto-X. Although difficult to test empirically, the SA selection
For every stock investor, the question of how many stocks to buy is fundamental. The recommendations from the literature is wide and ranges from 10 to over 300. As a contrast, 41.79% of Swedish shareholders held only one stock in year 2020. This thesis studies the Swedish stock market between 2011 and 2020 which to the authors knowledge not has been done before within the research space of Diversi
Purpose The purpose of this study is to establish a list of facilitating factors for the implementation of organisational innovations in healthcare units. We accomplish this by a thorough literary review, which is followed by an empirical case study of Capio Group. The case study is conducted to validate the theoretical findings, based on subjective perceptions of healthcare practitioners. This w
Background: Ventriculo-peritoneal (VP) shunt is a catheter which circulate flow of cerebrospinal fluid (CSF) from the lateral ventricle to the abdomen and it is the most commonly used shunt in modern neurosurgery. Complications of VP shunts are very common and often require emergency services. For the perioperative nurse this means that theVP shunt reoperation is one of the most often performed em
Development of genetically modified microorganisms such as Saccharomyces cerevisiae for use as microbial cell factories to produce fine and bulk chemicals has lately proceeded very rapidly, much thanks to new gene editing methods based on a CRISPR/Cas9 system adapted from bacteria which increases the rate of genetic engineering. However, development of methods which enable fast and simple screenin
Introduction: This study attempts to optimize the choice of stationary phase for the separation of lignosulfonate lignin compounds using supercritical fluid chromatography coupled to mass spectrometry. Background: Lignin is a potential renewable source of phenolic compounds. Lignosulfonate lignins are produced during pulping processes producing very complex mixtures, which are challenging to anal
Title: Critical Supply Chain Factors for Scaling a Startup -- A Case Study in the Industry of Semiconductors Author: Pontus Landgren Supervisors: Bertil Nilsson, Lund University, Faculty of Engineering & Lennart Moberg, Acconeer AB Background: A well implemented supply chain strategy aligned with the company's overall strategy is a prerequisite in order to successfully scale a startup.
Situated in the context of the global rise of the right and growing anti-feminist and anti-gender mobilization, this thesis explores the impacts of Jair Bolsonaro's right-wing populist government (2019-2022) on feminist activism in Brazil from an activist's perspective. It investigates the shifts and disruptions this government has entailed on three levels: in the realms of social public p
Digital technologies have significantly facilitated the creation and distribution of User Generated Content. Whereas the online environment offers promising opportunities for business and cultural development, it also carries important implications for EU copyright law. Whilst this topic has been explored in the literature, it is typically considered from the lens of rights holders, who often stru
Detta examensarbete undersöker hur ett business-to-business (B2B) inriktat företag som utvecklar ett direct-to-consumer (D2C) segment bör anpassa sin marknadsföringsstrategi för att växa genom marknadspenetration. Författarna har undersökt ett svensk kreditupplysningsföretag, Upplysningscentralen (UC), som har expanderat sin verksamhet till konsumentmarknaderna för kreditinformationstjänster och iThis thesis explores how a business-to-business (B2B) focused company should adapt the marketing strategy when transitioning into the direct-to-consumer (D2C) market, in order to grow through market penetration. The authors have examined a Swedish credit reference agency, Upplysningscentralen (UC), having expanded into the consumer markets of credit information and identity protection services – t
I present a theoretical model for competitive interaction between schools and grade inflation. To test the model, I estimate the effect of competition on grade inflation in Swedish upper secondary schools using data from all schools in the years 2012-2015. To solve the endogeneity problem of competition, I use Instrumental Variable estimation with Fixed Effects. I use the sudden shutdown of 17 sch
