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Biomolecules preserved in deep time have potential to shed light on major evolutionary questions, driving the search for new and more rigorous methods to detect them. Despite the increasing body of evidence from a wide variety of new, high resolution/high sensitivity analytical techniques, this research is commonly met with skepticism, as the long standing dogma persists that such preservation in
This book explores the concept of religious Enlightenment in the Nordic countries during the long eighteenth century. It argues that Lutheran confessional culture became intertwined with Enlightenment ideas and practices in this European region. In the book's three parts, specialist historians explore themes central to students of the early modern era - historical writing, material culture, eccles
Lung transplantation is the only option for patients with end-stage lung disease, but there is a shortage of available lung donors. Furthermore, efficiency of lung transplantation has been limited due to primary graft dysfunction. Recent mouse models mimicking lung disease in humans have allowed for deepening our understanding of disease pathomechanisms. Moreover, new techniques such as decellular
Ferromagnetic semiconductor thin layers of the quaternary (Ga,Mn)(Bi,As) and reference, ternary (Ga,Mn)As compounds, epitaxially grown under either compressive or tensile strain, have been characterized from a perspective of structural and magnetization homogeneity. The quality and composition of the layers have been confirmed by secondary-ion mass spectrometry (SIMS). A thorough evaluation of the
The Baltic Sea is one of the most eutrophied seas in the world, facing challenges with both hypoxia and algae blooms. In this study we analyse the effect of using different fishery policy instruments to reduce nutrient loads by removing fish biomass from the ecosystem. The study covers Danish, Finnish and Swedish pelagic fisheries. We distinguish between a private optimum maximising the net presen
ESA's Earth Explorer candidate mission A-SCOPE aims at observing CO2 from space with an active LIDAR instrument. This study employs quantitative network design techniques to investigate the benefit of A-SCOPE observations in a Carbon Cycle Data Assimilation System. The system links the observations to the terrestrial vegetation model BETHY via the fine resolution version of the atmospheric transpo
The paper presents a feasibility study for a Climate Prediction Data Assimilation System following the methodological approach of the Carbon Cycle Data Assimilation System (CCDAS). The usefulness of accurate gradient information for estimating process parameters of the spectral atmospheric circulation model PUMA on climate time-scales is investigated. Pseudo observations of the long-term mean surf
We present the DEAL language for heap assertions that are efficiently evaluated during garbage collection time. DEAL is a rich, declarative, logic-based language whose programs are guaranteed to be executable with good whole-heap locality, i.e., within a single traversal over every live object on the heap and a finite neighborhood around each object. As a result, evaluating DEAL programs incurs ne
The Absolut Company har öppnat besökscentret Absolut Home i Åhus och detta har potential att medföra ett stort antal värden för orten. Forskarna har studerat bådeturistaktörers och Åhusbors syn på värden för att ta reda på hur de ställer sig till det nya besökscentret i sin ort.
The production of continuously distributed X-rays by the impact of protons of 1.9-3.0 MeV for X-ray energies between 4 and 6.5 keV, and 1.9-2.65 MeV for X-ray energies between 1.7 and 4 keV has been investigated. Five different target types have been irradiated: polyethylene, polystyrene, carbon. KaptonTM and MylarTM. The results are presented as absolute cross sections for continuous X-ray produc
The fourth version of the Ariadne program for generating QCD cascades in the colour dipole approximation is presented. The underlying physics issues are discussed and a manual for using the program is given together with a few sample programs.The major changes from previous versions are the introduction of photon radiation from quarks and inclusion of interfaces to the LEPTO and PYTHIA programs.
Along with the review of the technological frame that will be available at the Extreme Light Infrastructure Attosecond Light Pulse Source (ELI-ALPS) we present considerations applicable to large-scale attosecond sources driven by high-power laser pulses.
Background: The aim of this study was to identify predictors of outcome after septoplasty in 888 patients from the Swedish National Septoplasty Register. Methodology: This is an observational register study analysing data from patients undergoing septoplasty in Sweden between 2015 and 2016. The patients reported severity of nasal obstruction (mild, moderate, severe) pre- and again 12 months postop
This book analyzes the current trends in the production, dissemination, and use of knowledge which contribute to social inequalities, especially in the Global South. The aim of the text is to explore the possibilities of active involvement by universities in the democratization of knowledge - a process by which people will be able to more easily acquire and utilize knowledge, as well as the result
The treatment of Parkinson's disease (PD) has for over 50 years relied on dopaminergic therapies that are highly effective especially in the early years of the condition, but ultimately are limited by the development of side effects that relate to the nonphysiological stimulation of dopamine receptors including in nonstriatal areas. Targeted regenerative therapies designed to restore specifically
Background: Epigenetic alterations have been recognized as important contributors to the pathogenesis of PDAC. However, the role of histone variants in pancreatic tumor progression is still not completely understood. The aim of this study was to explore the expression and prognostic significance of histone protein variants in PDAC patients. Methods: Liquid chromatography-tandem mass spectrometry (
Purpose: To set forth experiences in the context of the SERGS Pilot Curriculum—the first standardized educational program for robotic use in gynecological surgery—in terms of feasibility, effectiveness and potential for certification. Methods: The Society of European Robotic Gynecological Surgery (SERGS) outlined a Pilot Curriculum for standardized education in robot-assisted laparoscopic gynecolo
Lysosomal cell death is triggered by lysosomal membrane permeabilization (LMP) and subsequent release of lysosomal hydrolases from the lysosomal lumen into the cytosol. Once released into the cytosol, the lysosomal cathepsin proteases act as executioner proteases for the subsequent cell death-either autonomously without caspase activation or in concert with the classical apoptotic machinery. Lysos
The FemtoMAX beamline facilitates studies of the structural dynamics of materials. Such studies are of fundamental importance for key scientific problems related to programming materials using light, enabling new storage media and new manufacturing techniques, obtaining sustainable energy by mimicking photosynthesis, and gleaning insights into chemical and biological functional dynamics. The Femto
