Filtyp
The Period genes (Per) play essential roles in modulating the molecular circadian clock timing in a broad range of species, which regulates the physiological and cellular rhythms through the transcription-translation feedback loop. While the Period gene paralogs are widely observed among vertebrates, the evolutionary history and the functional diversification of Per genes across vertebrates are no
This master’s thesis has examined the feasibility of an accumulator-based actuation method for the BorgWarner (BW) electric torque vectoring and disconnect (eTVD) system. The requirements for the proposed concepts were defined based on the performance of the baseline eTVD and served as reference criteria throughout the development process. A strong emphasis was placed on reducing system complexit
Bacterial infection and hemorrhage remain significant clinical challenges for chronic wounds, despite advancements in antimicrobial strategies and materials. Herein, 980 nm-laser-responsive photothermal conjugated polymers (CPs) are combined with chitosan-based cryogels (CP@Gel) to achieve rapid hemostasis and efficient anti-infectious performance. CP nanoparticles (CP NPs) were prepared by nanopr
Continuous non-invasive monitoring of respiratory rate in laboratory mice can support research across drug efficacy, sleep, and stress and pain assessment. Established respiratory rate estimation methods exist but many conflict with the 3Rs principle through invasiveness, motion restriction, or animal stress. A cross-method comparison between two non-invasive systems on the same freely-moving anim
In northern countries, the climate, and consequently the use of studded tyres and winter traction sanding, causes accumulation of road dust over winter and spring, resulting in high PM10 concentrations during springtime dusting events. To quantify the dust at the road surface, a method—the wet dust sampler (WDS)—was developed allowing repeatable sampling also under wet and snowy conditions. The pr
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of individualized developmental care interventions for promoting development and preventing morbidity in preterm infants.
In this paper, we present a method for in situ coating of individual protein particles in a respirable size. The aim of the coating was to influence the particle/powder properties, and to reduce or prevent surface-induced conformational changes of the protein, during spray-drying, which was the method used for simultaneously preparing and coating particles. The investigated formulations included b
Climate change and the resulting warming caused by human activities, such as releasing greenhouse gases (GHG), notably carbon dioxide (CO2), are paramount concerns in the contemporary era. Therefore, it is essential to understand spatial and temporal variations of atmospheric carbon dioxide concentration (XCO2) on national and international scales and the role of controlling variables. This resear
OBJECTIVE: Sarcopenia (loss of muscle strength/mass) reduces physical performance (walking, strength, mobility) and is common in Parkinson's disease (PD), but data on newly diagnosed, untreated patients ("de novo") are scarce. Fatigue is frequent in PD and linked to physical decline and malnutrition, key sarcopenia risk factors. We aimed to describe sarcopenia prevalence, malnutrition risk, and fa
Aerosolised Polystyrene Latex (PSL) nanoparticles are, due to their well-defined size, spherical shape, and inert surface, useful in many experimental applications, including studies of particle deposition in the human lung. Aerosolising nanoparticles entails added challenges, and nanoparticles can potentially be more hazardous than otherwise equivalent microparticles. The objective of this work w
Implant-associated infections (IAIs) are one of the leading concerns in orthopedics and dentistry as they commonly lead to implant failure. The presence of biofilms and, increasingly frequently, drug-resistant bacteria further impairs the efficacy of conventional antibiotics. Immobilization of antimicrobial peptides (AMPs) on implant surfaces is a promising alternative to antibiotics for preventio
Self-care interventions for sexual and reproductive health (SRH), including HIV self-testing, self-injected contraception and self-managed abortion, offer promising pathways to advance universal health coverage, particularly in low- and middle-income countries. While often framed as cost-saving measures, this paper argues that self-care should be understood as a strategic investment in health syst
The structural integration of energy storage could play a pivotal role in designing more efficient, lightweight systems such as electric transport, internet of things (IoT) devices and autonomous systems. The current work focuses on the fabrication and characterization of novel multifunctional composites for sodium-ion structural batteries. A PEO-PVP polymer matrix with added InAs nanowires and gl
Stabell and Fjeldstad (1998) proposed three value configurations; the value shop, the value chain and the value network based on Thompson’s (1967) three technologies as a typology. However, that Thompson’s technologies constitute a typology has been criticized (cf Barbini and Neri, 2017). Also, research has highlighted increased shifts in value configurations and hybrid forms. Thus, the question a
The increasing use of digital tools in archaeology has vastly expanded our capacity to document and visualise the past, yet the reasoning that connects evidence to interpretation often remains implicit or undocumented. This paper addresses that gapby integrating Inference to the Best Explanation (IBE)—a philosophical model of hypothesis evaluation—into the Archaeological Interactive Report (AIR),
