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Each year millions of people receive emergency relief items from humanitarian organizations following disasters and crises. While significant time and resources have been invested in identifying the needs of affected populations and how to address those needs, significantly less focus has been given to environmental impacts of these response operations. These impacts can result in substantial nega
Parkinson’s disease (PD) is considered one of the most frequent neurodegenerative disorders amongst elderly people. PD leads to loss of dopaminergic neurons in substantia nigra of the brain giving symptoms such as slowness of movement and dementia. PD brains have been found to contain accumulations of a protein named alpha‐synuclein (α‐syn). Additional to its aggregation propensity in PD it is als
This thesis investigates how impact assessment can contribute to organisational learning and whether there are ways to enhance it. To answer these questions, the research takes a form of a qualitative case study carried out in collaboration with the non-profit organisation Reach for Change which represents a single case. The research data is drawn from two primary sources of evidence: organisation
In a world where the problem of energy resources, pollution and all aspects related to these issues becomes more and more dominant, a greater commitment is needed in the search for solutions. The goal of this project is to make a contribution to the research and development of new materials to reduce the environmental impact in some fields. First of all, we tried to synthesize and prepare an isati
Studying gene-lifestyle interaction may help to identify lifestyle factors that modify genetic susceptibility and uncover genetic loci exerting important subgroup effects. Adequately powered studies with prospective, unbiased, standardised assessment of key behavioural factors for gene-lifestyle studies are lacking. This case-cohort study aims to investigate how genetic and potentially modifiable
To describe the relatives' experiences of information and support while heart or lung transplant candidates were waiting for a transplantation.
The synthesis of four molybdenum and tungsten complexes bearing tetradentate tripodal amino bisphenolate ligands with either hydroxyethylene (1a) or hydroxyglycolene (1b) substituents is reported. The molybdenum dioxo complexes [MoO2L] (L = 2a, 2b) and tungsten complexes [WO2L] (3a, 3b) were synthesized using [MoO2(acac)(2)] and [W(eg)(3)] (eg = 1,2-ethanediolato, ethylene glycolate), respectively
It is of highest importance to find proteins responsible for breast cancer dissemination, for use as biomarkers or treatment targets. We established and performed a combined nontargeted LC MS/MS and a targeted LC SRM workflow for discovery and validation of protein biomarkers. Eighty breast tumors, stratified for estrogen receptor status and development of distant recurrence (DR +/-), were collect
This review will discuss methodologies and applicability of key inflammatory models of respiratory disease in proof of concept or proof of efficacy clinical studies. In close relationship with these models, induced sputum and inflammatory cell counts will be addressed for phenotype-directed drug development. Additionally, important regulatory aspects regarding noninvestigational medicinal products
Energy-rich methane can be harnessed from seaweed deposits by anaerobic digestion. However, the high heavy metal content in the seaweed and its digestates limits their use as fertilisers. Heavy metal contaminants from solid seaweed can be removed by, mobilisation into a liquid phase and subsequent metal ions adsorption. In this laboratory-scale study, pretreatment strategies for enhancing seaweed
Background More effective prevention of suicide requires a comprehensive understanding of sociodemographic, psychiatric and somatic risk factors. Previous studies have been limited by incomplete ascertainment of these factors. We conducted the first study of this issue using sociodemographic and out-patient and in-patient health data for a national population. Method We used data from a national c
Sweden has experienced a national value-based pricing (VBP) system for innovative outpatient drugs operated by the Pharmaceutical Benefits Board - LFN (now called the Dental and Pharmaceutical Benefits agency - TLV) since 2002. VBP has the character of a monopoly system, leading to reimbursement decisions where usage of new medicines is limited to subgroups and not the population for which the dru
This paper represents the opinion of a group of researchers and clinicians with an established interest in poststroke care and is based on the recognised need for long-term care following stroke, especially in view of the global increase of disability due to stroke. Among the more frequent long-term complications following stroke are spasticity-related disabilities. Although spasticity alone occur
This paper analyses the potential, barriers and limitations for regional innovation policy to facilitate industrial renewal in old industrial regions. It draws on a case analysis of the policy programme ‘Biorefinery of the Future’ geared to promote renewal of the forest industry in Northern Sweden. It is shown that infusion of radical emergent technology is necessary for new regional path developm
Macroporous sponge-like gelatin-fibrinogen (Gl-Fg) scaffolds cross-linked with different concentrations (0.05-0.5%) of glutaraldehyde (GA) were produced using cryogelation technology, which allows for the preparation of highly porous scaffolds without compromising their mechanical properties, and is a more cost-efficient process than freeze-drying. The produced Gl-Fg-GA(X) scaffolds had a uniform
Abstract in UndeterminedPiece rate and performance based wage systems are common in the construction industry. Construction workers are known to have an increased risk of pain and musculoskeletal disorders (MSD). In this cross-sectional questionnaire study, we examined the association between wage system and (1) physical exertion, (2) time pressure, (3) pain, and (4) fatigue. The participants comp
We consider a purchase/inventory control problem in which the purchase price and demand are stochastic, a common situation encountered by firms that replenish in a foreign currency or from commodity markets. More specifically, we assume that the demand follows a Poisson arrival process and that the log-price evolves according to a general Wiener process. Under these circumstances, the optimal poli
Gender stereotypes describe women as communal and men as agentic. Laboratory-based research (Rudman & Glick, 1999, 2001) suggests that trying to disconfirm such descriptive gender stereotypes (e.g., women self-promoting their agency), entails the risk of hiring discrimination due to violation of prescriptive gender stereotypes: a backlash. To examine whether backlash occurs when applying for r
Specimens of Caloplaca belonging to the group of C. citrina (Hoffm.) Th. Fr. were collected in different localities in the provinces of Buenos Aires (Argentina) and studied using morphology and nrITS data. They were identified as C. austrocitrina Vondrak, Riha, Arup & Sochting, a species newly described from the Black Sea area, but also found in other European countries. These findings are the
