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Chemokines are important in the development and progression of tumors. We investigated the expression of CXCL14 and CXCL16 in colon cancer. Expression of mRNA was assessed in primary tumors and lymph nodes and CXCL16 mRNA levels were correlated to patient’s survival. Protein expression was investigated by two-color immunofluorescence and immunomorphometry. CXCL14 and CXCL16 mRNA levels and protein

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Fredrik NG Andersson and Lars Jonung argue that the current push for fiscal activism is short-sighted. Instead, the Swedish case from the last 25 years shows that stable public finances combined with supply-side policies is the recipe for economic stability and growth.

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WNT5A is a well-known mediator of melanoma cell invasion and metastasis via its ability to activate protein kinase C (PKC), which is monitored by phosphorylation of the endogenous PKC substrate myristoylated alanine-rich c-kinase substrate (MARCKS). However, a possible direct contribution of MARCKS in WNT5A-mediated melanoma cell invasion has not been investigated. Analyses of melanoma patient dat

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The introduction first explains the rationale and theoretical and empirical contributions of the edited volume. The book seeks to address a considerable gap of knowledge of the nature of the relationship between institutions governing the climate-energy nexus in a multilevel context. In particular, there is scant research on consequences on the legitimacy and effectiveness of governance arrangemen

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This project consists of a thorough study of an energy efficient and moisture safe row-house, located in the Nordic climate of Sweden. Climate and site analysis, building scale design decisions and finally the evaluation and optimization of its energy performance were different steps of a holistic process aiming at the architectural quality, energy efficiency, comfort and the well-being of users.

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This review focuses on the most recent literature concerning flow cytometry (FCM) application for diagnosis of myelodysplastic syndrome (MDS). Aberrant FCM results have been defined as abnormalities in at least three tested features comprising at least two bone marrow (BM) cell compartments. FCM results should be interpreted together with the BM smear cytology, the morphological assessment of BM b

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In linguistics and in the philosophy of language it is standardly assumed that know is a factive verb, meaning that a sentence such as X knows that p, when uttered in its positive declarative form, presupposes, in fact entails, the truth of its complement. A problem for this analysis is the fact that the verb know can be used non-factively in contexts where it is evident that the proposition expre

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Purpose: The FANCM c.5101C>T nonsense mutation was previously found to associate with breast cancer in the Finnish population, especially among triple-negative cases. Here, we studied the prevalence of three other FANCM variants: c.5791C>T, which has been reported to predispose to familial breast cancer, and the c.4025_4026delCT and c.5293dupA variants recently identified in Finnish cancer patient

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The intramedullary skeletal kinetic distractor (ISKD) is one of the relatively recent methods developed to overcome the complications of conventional bone lengthening methods, such as external fixators. These complications include pain, muscle transfixation, pin-tract infection, reduced joint motion, and prolonged fixation time. However, ISKD-specific complications such as uncontrollable lengtheni

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Climate change and direct anthropogenic impact are recognized as two major factors affecting catchment runoff. This study investigated the separate effect of each of these factors for runoff from the important Tunisian Merguellil catchment. For this purpose, more than forty years of hydrological data were used. The methodology was based on hydrological characterization, NDVI index to monitor land

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Transitions to low-carbon energy technologies and other forms of climate mitigation tend to involve disempowerment and environmental injustices of various kinds. This paper argues that such tendencies are inherent in the social rationale of technological systems promoted by the logic of the world market. The production and operation of technological artifacts are imbued with economic rationality a

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Usually the mel-frequency cepstral coefficients (MFCCs) are derived via Hamming windowed DFT spectrum. In this paper, we advocate to use a so-called multitaper method instead. Multitaper methods form a spectrum estimate using multiple window functions and frequency-domain averaging. Multitapers provide a robust spectrum estimate but have not received much attention in speech processing. Our speake

Benign Gynekologisk Minimalinvasiv Kirurgi

Andrea Stuart är gynekolog med fokus på benign gynekologisk kirurgi och utveckling av minimalinvasiva metoder. Hon leder flera stora kliniska studier, bland annat den internationella RCT:n VANOLAH, som jämför vNOTES med vaginal kirurgi och laparoskopi för hysterektomi, samt den multinationella ADNOLA-studien där laparoskopi ställs mot vNOTES vid äggstockskirurgi för att optimera metodval och förbäAndrea Stuart is a gynecologist specializing in benign gynecological surgery, focusing on developing and comparing minimally invasive techniques. She leads a large international RCT comparing vNOTES with vaginal surgery and laparoscopy to determine which hysterectomy method offers the best outcomes and lowest complication rates. She also heads a multinational RCT comparing laparoscopy with vNOTES