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BACKGROUND: Despite decades of initiatives promoting individual behavior change, obesity rates remain high and continue to rise globally, indicating that what is commonly labelled as “obesity prevention” is not, in practice, preventing obesity. While health promotion strategies and policy interventions have demonstrated improvements in environments, health behaviors, and industry practices, their
Purpose: Radiotherapy (RT) for patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC) can be intensified by delivering 6 (6fx/w) instead of 5 (5fx/w) fractions per week. Randomized trials have demonstrated superiority for 6fx/w in patients treated without concurrent chemotherapy (CRT). This real-world analysis compares 6 vs 5 fx/w in LA-HNSCC all-comers, treated predominan
The brain has a tremendous capacity to adapt (i.e., plasticity) to environmental changes or injury. This capacity decreases with age but is never lost. The goal of sensory relearning is to improve hand function by using the dynamic capacity of the brain with the use of guided plasticity (i.e., plasticity used for a therapeutic purpose). After a peripheral nerve injury, no nerve signals are sent fr
Deterministic lateral displacement (DLD) and related microfluidic sorting devices are typically evaluated based on the size distributions of particles collected at each outlet, even though the more relevant measure of performance is the probability that a particle of a given size ends up in a specific outlet. Here, we use Bayes’ rule to infer these size-dependent routing probabilities from experim
Rehabilitering efter en stroke är viktig för att den drabbade individen ska återfå så stor del av de påverkade kroppsfunktionerna som möjligt. Balansen blir ofta försämrad hos individer som överlevt stroke och behöver stärkas för att inte hindra individen i dennes vardagliga liv. Rehabiliteringsträningen av balansen bör innehålla motivationsfaktorer för att träningen ska ske i tillräckligt stor omThe rehabilitation after a stroke is important for the individual so that the affected body functions recover as much as possible. The balance is often impaired after a stroke and need to be strengthend to not impede the stroke-survivor in the daily life. The rehabilitation training of the balance should include motivation factors for the training to take place in sufficiently large scale. The aim
The emergence of cyber mistreatment among frontline workers in their digital interactions with customers, clients and patients represents a significant but relatively new work environment risk within the service sector. Human resource management has a key role in digital transformation, which includes securing safe and healthy workplaces and fostering sustainable practices for handling cyber mistr
This Perspective suggests six conceptual propositions to advance care-centric planning and governance in support of SDG 11. By prioritizing relationships, responsiveness, and collective well-being, while also integrating empowerment, environmental stewardship, and cultural diversity, a care-centric approach fosters more inclusive and sustainable cities. Drawing on selected practice-based examples,
Spine Computed Tomography (SCT) is essential for identifying fractures, tumors and degenerative spine diseases, assisting medical practitioners in formulating an accurate diagnosis and treatment. One of the core element of SCT is reporting. The effectiveness of spine reporting is often limited by challenges such as an inadequate infrastructure and lack of experts. Automated SCT analysis has the po
This ESMO CPG provides key recommendations and algorithms for managing DLBCL, FL, HL, MCL, MZL, PCNSL and PTCL. •It covers epidemiology, diagnosis, staging, risk assessment, treatment of primary and refractory disease and follow-up. •Treatment algorithms for each lymphoma type are provided. •The author group encompasses a multidisciplinary group of experts from different institutions and countries
Surface tension is crucial for nanowire vapor liquid solid (VLS) growth models and simulations of growth under external stimuli. A promising method involving imaging droplet deformation under an external electric field has previously been used to report the surface tension of the AuSi eutectic catalyst on Si-nanowires. However, simplified assumptions in this approach led to a significantly lower v
Objective: The aim of this study was to explore experiences and challenges in handling feedback and criticism among early career surgeons. Design: This study is part of a prospective, exploratory, longitudinal study evaluating surgical residents throughout residency. Semi-structured interviews were conducted with medical doctors applying to a locum or residency position in a surgical specialty. An
The rapid growth of smart logistics, driven by IoT devices and data-intensive applications, necessitates secure, scalable, and efficient computing frameworks. As the edge-fog-cloud (EFC) paradigm supports real-time data processing, it faces significant security threats and attacks, including privacy risks, data breaches, and unauthorized access. To address these security threats and attacks, block
The advent of AlphaFold and consumer large language models have elicited unprecedented development of artificial intelligence (AI). AI has had substantial impact in every area of research, including in molecular biology. This is principally in thanks to contributions to the Protein Data Bank and various genome sequence databases, providing an astronomical amount of data for model training. These d
Alzheimer’s disease (AD) is the most common neurodegenerative disorder, affecting millions worldwide. The clinical presentation of AD is heterogenous and often complicated by the presence of multiple co-pathologies, which can overlap with features of other neurodegenerative disorders, underscoring the need for tools to aid accurate and timely diagnosis. Biomarkers for AD span multiple modalities a
Background and purpose: Neuroblastoma is the most common extracranial solid tumour in children. Radiotherapy is commonly part of the multimodal treatment for high-risk patients. The aim of this study is to analyse doses to organs at risk (OAR) in comparative proton and photon treatment plans for children treated for neuroblastoma and report side effects. Patient/material and methods: All children
