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A Population-Based Study of Hepatitis D Virus as Potential Risk Factor for Hepatocellular Carcinoma.

Hepatitis D virus (HDV) is dependent on the presence of hepatitis B virus (HBV) for transmission and replication because of its inability to produce its own coat. It remains unclear whether HDV infection increases the risk of hepatocellular carcinoma. Using the Swedish Hospital Discharge Register and Outpatient Registry, we identified 9160 patients with chronic HBV infection between 1997 and 2008,

Risk of pulmonary embolism in patients with autoimmune disorders: a nationwide follow-up study from Sweden.

BACKGROUND: Some autoimmune disorders have been linked to venous thromboembolism. We examined whether there is an association between autoimmune disorders and risk of pulmonary embolism. METHODS: We followed up all individuals in Sweden without previous hospital admission for venous thromboembolism and with a primary or secondary diagnosis of an autoimmune disorder between Jan 1, 1964, and Dec 31,

Protective Effects of Pregnancy on Risk of Alcohol Use Disorder

OBJECTIVE:: The authors sought to clarify the etiology of the association between pregnancy and reduced risk of alcohol use disorder. METHODS:: The authors used data from longitudinal population-wide Swedish medical, pharmacy, and criminal registries to evaluate whether rates of alcohol use disorder are lower during pregnancy. They compared pregnant women born between 1975 and 1992 (N=322,029) wit

Gestational age at birth and mortality from infancy into mid-adulthood : a national cohort study

Background: Breakthroughs in the treatment of preterm birth approximately 40 years ago have enabled a generation of preterm survivors to now reach mid-adulthood. Understanding their health sequelae is essential for guiding their long-term care. We did a study to examine preterm birth in relation to mortality into mid-adulthood. Methods: A national cohort study was done of all 4 296 814 singleton l

Mapping challenges and opportunities for aggregating information on systemic risks from multiple stakeholders

The Sendai Framework for Disaster Risk Reduction highlights the importance of all-hazard and multi-stakeholder approaches. This requires exchange and integration of risk information across sectorial and administrative borders. This paper focuses on challenges and prerequisites for aggregating risk information from multiple stakeholders in disaster risk management systems. Aggregation is here under

Scrutinizing the relationship between adaptation and resilience : Longitudinal comparative case studies across shocks in two Nepalese villages

Growing concerns regarding the vulnerability of communities to natural disasters and climate-related hazards and risks have caused attention to be increasingly directed towards adaptation and resilience as important policy prescriptions. These two concepts are commonly becoming normative when used in this context and seen as intrinsically linked to each other, i.e. adaptation leads to resilience a

Capability assessments - How to make them useful for decision-making

Capability assessments are becoming increasingly common as part of risk management activities worldwide. Despite this, there is no consensus concerning how these assessments are best conducted and presented. Recent studies suggest that two factors may influence the usefulness of capability assessments for decision-making: namely, whether the assessment includes descriptions of the resources availa

Risk of second primary cancer following myeloid neoplasia and risk of myeloid neoplasia as second primary cancer : a nationwide, observational follow up study in Sweden

Background: Although advances in the treatment of myeloid neoplasms have led to improved patient survival, this improvement has been accompanied by an increased risk of second primary cancer (ie, the risk of another cancer after myeloid neoplasia). We aimed to assess bi-directional associations between myeloid cancers and other cancers—ie, development of second primary cancer in patients who have

Pilotförsök för generell övervakning av pollinatörer – resultat för fältsäsongen 2021

Lunds universitet har på uppdrag av Naturvårdsverket under 2021 utvärderat metodik för nationell pollinatörsövervakning. Metodiken bygger på rapporten ”Proposal for an EU pollinator monitoring scheme” som tagits fram av en expertgrupp inom EU (Potts m. fl. 2020) och ska kunna ge underlag för uppföljning av pollinatörer på nationell nivå med ett främsta fokus på landskapet utanför områden som omfat

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Streptococcus pneumoniae (pneumococcus) is an asymptomatic colonizer of the nasopharynx in most individuals but can progress to a pulmonary and systemic pathogen upon influenza A virus (IAV) infection. Advanced age enhances host susceptibility to secondary pneumococcal pneumonia and is associated with worsened disease outcomes. The host factors driving those processes are not well defined, in part

Sharpen existing tools or get a new toolbox? Contemporary cluster initiatives and regional transformation

This paper explores the evolving landscape of regional innovation policy, focusing on the interplay between traditional cluster policies and emerging transformative agendas. Over the past decade, policy initiatives aimed at fostering place-based, collaborative innovation have proliferated. However, questions arise regarding the adequacy of existing policy tools in accommodating newer, transformati

"What's the problem?"-Toward a framework for collective problem representation in emergency response management

Responding to today's often transboundary emergencies, frequently characterized by unclear root causes and indistinct responsibilities as well as multiple actors, will require that responding actors come together to meet societal needs and solve problems arising in relation to those needs. In collective problem solving, representing the problem is crucial, especially in emergency situations, where

Influence of the Polysaccharide Capsule on the Bactericidal Activity of Indolicidin on Streptococcus pneumoniae.

Streptococcus pneumoniae is a pathogen responsible for high morbidity and mortality worldwide. The polysaccharide capsule confers protection against phagocytosis and influences many aspects of pneumococcal pathogenesis. The capsular polysaccharides (CPS) are highly immunogenic and exhibit great structural variability, with more than 100 serotypes described so far. Antimicrobial peptides (AMPs) ar

Evaluation of diagnostic performance of non-invasive HIV self-testing kit using oral fluid in Addis Ababa, Ethiopia : A facility-based cross-sectional study

BACKGROUND: Human immunodeficiency virus (HIV) testing is critical for early linkage to treatment and care services. However, there is a substantial gap in HIV testing, particularly in resource limited settings due to low accessibility of HIV testing sites, inconvenient testing hours, and concerns about loss of confidentiality. Thus, adopting new strategies such as HIV self-testing (HIVST) could o

Problem gambling in the fitness world—a general population web survey

The world of sports has a complex association to problem gambling, and the sparse research examining problem gambling in athletes has suggested an increased prevalence and particularly high male predominance. The present study aimed to study frequency and correlates of problem gambling in populations with moderate to high involvement in fitness or physical exercise. This is a self-selective online

Exercise is medicine : Primary care counseling on aerobic fitness and muscle strengthening

Patient counseling on physical fitness remains underutilized in primary care, despite its clinical and cost effectiveness. Most counseling interventions have focused on aerobic activity and neglected another vital component of physical fitness, muscle strengthening, which has recently been shown to be independently protective against cardiometabolic diseases and premature mortality. This article r