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Predicting troponin biomarker elevation from electrocardiograms using a deep neural network

Background Elevated troponin levels are a sensitive biomarker for cardiac injury. The quick and reliable prediction of troponin elevation for patients with chest pain from readily available ECGs may pose a valuable time-saving diagnostic tool during decision-making concerning this patient population. Methods and results The data used included 15 856 ECGs from patients presenting to the emergency r

Multidimensional chemistry coordinate mapping for Large Eddy Simulations of a turbulent premixed bluff-body burner

In numerical combustion research, accurate chemical reaction mechanisms for heavy hydrocarbons are essential to investigate the flame dynamics of Sustainable Aviation Fuels (SAF) relative to conventional jet fuels. However, accounting for hundreds or thousands of reactions makes Finite-Rate Chemistry (FRC) Large Eddy Simulations (LES) impractical for realistic engineering scenarios. In the present

Support, not automation : towards AI-supported code review for code quality and beyond

Code review is a well-established and valuable software development practice associated with code quality, interpersonal, and team benefits. However, it is also time-consuming, with developers spending 10–20% of their working time doing code reviews. With recent advances in AI capabilities, there are more and more initiatives aimed at fully automating code reviews to save time and streamline softw

The accuracy of forecasted hospital admission for respiratory tract infections in children aged 0–5 years for 2017/2023

Aim: Healthcare services are in need of tools that can help to ensure a sufficient capacity in periods with high prevalence of respiratory tract infections (RTIs). During the COVID-19 pandemic, we forecasted the number of hospital admissions for RTIs among children aged 0–5 years. Now, in 2024, we aim to examine the accuracy and usefulness of our forecast models. Methods: We conducted a retrospect

Ultra-processed food consumption, plasma metabolite profile, and risk of all-cause and cause-specific mortality in a population-based cohort

Background & aims: Epidemiological evidence on ultra-processed food (UPF) and cause-specific mortality remains limited and mixed. Molecular mechanisms underlying UPF intake and mortality remain unexplored. This study aimed to evaluate the associations between UPF consumption, metabolic signatures, and all-cause, premature, and cause-specific mortality. Methods: This study included 27670 partic

Prevalence of sexually transmitted infections and associated risk factors among female sex workers in Guinea-Bissau

Objective To estimate the prevalence of the curable sexually transmitted infections (STIs) Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis and Treponema pallidum, to identify associated risk factors and to assess ciprofloxacin resistance in N. gonorrhoeae-positive specimens among female sex workers (FSWs) in Guinea-Bissau. Methods For this cross-sectional

Evaluation of 5G Readiness for Critical Control of Remote Devices

This paper presents a comprehensive evaluation of various wireless networks for Teleoperated Driving (ToD) applications, focusing on a hoverboard as a test vehicle. The study compares end-To-end delay and jitter across five network setups: A private 5 G network, a wireless LAN, a public LTEA network, and two wireless CANs, based on the service level requirements outlined by the 5G Automotive Assoc

Embedded disposability : A cultural political economy of plastics

Plast präglar i stort sett allting i det moderna livet och bidrar till miljöförstöring och avfallsgenerering på global nivå. Denna avhandling undersöker hur plastavfall blev djupt inbäddat i Sveriges kulturella, politiska och ekonomiska strukturer. Med hjälp av ett ramverk baserat på kulturell politisk ekonomi (CPE) används tre perspektiv - hegemoni, inlåsningseffekter och praktiker - för att analPlastic disposability is a pervasive feature of modern life, contributing to environmental degradation and waste generation on a global scale. This dissertation investigates how plastic disposability became deeply embedded within Sweden's cultural, political, and economic structures. Using a Cultural Political Economy (CPE) framework, it applies three lenses – hegemony, lock-in, and practice – to

EzSkiROS : enhancing robot skill composition with embedded DSL for early error detection

When developing general-purpose robot software components, we often lack complete knowledge of the specific contexts in which they will be executed. This limits our ability to make predictions, including our ability to detect program bugs statically. Since running a robot is an expensive task, finding errors at runtime can prolong the debugging loop or even cause safety hazards. This paper propose

Performance of a point-of-care ultrasound platform for artificial intelligence-enabled assessment of pulmonary B-lines

Background: The incorporation of artificial intelligence (AI) into point-of-care ultrasound (POCUS) platforms has rapidly increased. The number of B-lines present on lung ultrasound (LUS) serve as a useful tool for the assessment of pulmonary congestion. Interpretation, however, requires experience and therefore AI automation has been pursued. This study aimed to test the agreement between the AI

Independent validation of four-dimensional flow MR velocities and vortex ring volume using particle imaging velocimetry and planar laser-Induced fluorescence. : Validation of 4D Flow using PIV and PLIF

PURPOSE:This study aimed to: (i) present and characterize a phantom setup for validation of four-dimensional (4D) flow using particle imaging velocimetry (PIV) and planar laser-induced fluorescence (PLIF); (ii) validate 4D flow velocity measurements using PIV; and (iii) validate 4D flow vortex ring volume (VV) using PLIF.METHODS:A pulsatile pump and a tank with a 25-mm nozzle were constructed. PIV

Unresolved grief and its consequences. A nationwide follow-up of teenage loss of a parent to cancer 6-9 years earlier.

PURPOSE: The early loss of a parent is a tragedy and a serious life event. This study investigated grief resolution and morbidity in cancer-bereaved teenagers 6 to 9 years after the loss of a parent to cancer. METHODS: In a nationwide population-based study of 622 of 851 (73 %) youths who as teenagers 6 to 9 years earlier had lost a parent to cancer, we explored the magnitude of unresolved grief a

Acoustic Enrichment of Extracellular Vesicles from Biological Fluids

Extracellular vesicles (EVs) have emerged as a rich source of biomarkers providing diagnostic and prognostic information in diseases such as cancer. Large-scale investigations into the contents of EVs in clinical cohorts are warranted, but a major obstacle is the lack of a rapid, reproducible, efficient, and low-cost methodology to enrich EVs. Here, we demonstrate the applicability of an automated

Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover

Aims/hypothesisPPARGC1A encodes peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α), a central regulator of energy metabolism and mitochondrial function. A common polymorphism in PPARGC1A (rs8192678, C/T, Gly482Ser) has been associated with obesity and related metabolic disorders, but no published functional studies have investigated direct allele-specific effects in adipocyte bi

Is Performance Measurement and Management fit for the future?

Purpose: The aim of this paper is to find out how the PMM system can be used to remain resilient to a change in the environment and so continue to provide appropriate guidance to managers in real time. Methodology: The paper is based on a qualitative research method with primarily an abductive approach to derive insight about a PMM system’s use to remain resilient to a change in the environment.

Yttrandefrihet i Turkiet utifrån två rättsfall - En argumentationsanalys av två rättsfall om yttrandefrihet i Turkiet och hur de förhåller sig till de samhällsfunktionella teorierna sannings-, demokrati- och toleransargumenten

Syftet med denna kandidatuppsats är att få en djupare förståelse för hur Turkiet har hanterat yttrandefriheten. Denna undersökning analyserar två rättsfall där Europeiska domstolen för de mänskliga rättigheterna fastställde att Turkiet misslyckats i sin skyldighet att skydda yttrandefriheten för två av sina medborgare, Hrant Dink och Selahattin Demirtaş. Undersökningen inleds med att analysera rätThe purpose of this bachelor thesis is to gain a deeper understanding of how Turkey has dealt with freedom of expression. This study analyzes two court cases in which the European Court of Human Rights determined that Turkey failed in its obligation to protect the freedom of expression of two of its citizens, Hrant Dink and Selahattin Demirtaş. The study begins by analyzing the merits of the cases

Svensk lagstiftning om ansvarsgenombrott i ABL - varför inte?

I Sverige är aktiebolaget idag vår vanligaste associationsform och fördelarna är många. Den förmod¬ligen starkaste av dem är regeln om det begränsade ansvaret för aktieägare. Genom denna regel åtnjuter aktieägare skydd mot att behöva gälda bolagets borgenärer med mer än det redan satsade aktiekapitalet. Med detta som bakgrund kan det begränsade ansvaret sägas vara en direkt förutsättning för förveIn Sweden, the most common type of company is the limited stock company (aktiebolag), which brings about several advantages. The strongest one is probably the shareholders’ limited liability. By this rule, the stock owners acquire protection from having to atone for any company debt exceed¬ing the already submitted equity stock. Keeping this in mind, one can consider the limited liability being an

No socioeconomic disparities in the availability of personal care assistance : a population-based cohort analysis of children living with respiratory support

Background: Children aged 0–18 years who need long-term respiratory support rely on medical technology and comprehensive medical care. For this care to be provided at home, access to medical and social support and care is essential. In Sweden, the most notable form is personal care assistance (PCA), which is granted based on legislation and individual authority decisions. We aim to explore the imp