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The modelling of large systems is greatly simplified if their hierarchical decomposition and interconnection structure can be described graphically. The paper describes a system allowing input of block diagrams and continuous zooming to view internal details. Model equations are automatically transformed to assignment statements when possible, allowing efficient explicit integration routines to be
Modern antenna design for communication systems revolves around two extremes: devices, where only a small region is dedicated to antenna design, and base stations, where design space is not shared with other components. Both imply different restrictions on what performance is realizable. In this paper properties of both ends of the spectrum in terms of MIMO performance is investigated. For small a
Background: Numerous different types of variations can occur in DNA and have diverse effects and consequences. The Variation Ontology (VariO) was developed for systematic descriptions of variations and their effects at DNA, RNA and protein levels. Results: VariO use and terms for DNA variations are described in depth. VariO provides systematic names for variation types and detailed descriptions fo
The Arctic is often perceived as the new resource frontier in a resource hungry world. Many actors both inside and outside the region are eager to know what opportunities lie under the ice, and many claim a say in the future development of the Arctic. In Greenland, a national economy based on natural resources will lessen the dependence on the former colonial power Denmark. Many consider this an i
Modern programs make extensive use of reusable software libraries. For example, a study of a number of large Java applications shows that between 17% and 30% of the classes in those applications use container classes defined in the java.util package. Given this extensive code reuse in Java programs, it is important for the interfaces of reusable classes to be well documented. An interface is well
Label: Proprius PRCD 2083
Label Euterpe Musica EMCD 1316
Randomized clinical trials are the preferred study design to address key research questions about the benefits or harms of interventions. However, randomized trials of oxygen therapy are difficult to conduct and have limitations. The purpose of this article is to offer our view on the potential use of patient registries in the field of home oxygen in COPD as an alternative to randomized trials by
Global in its outlook, this Research Agenda systematically reviews and critiques existing research on sustainable cities, calling for greater engagement with a diversity of perspectives. It interrogates foundational assumptions in the field and offers reframed perspectives on sustainability. Chapters also explore diverse approaches, actors and domains, locating emerging dynamics and new directions
This paper investigates employment outcomes for a large sample of Ph.D. students who were enrolled in a doctoral training program in Italy in the period 2008–14. The empirical analysis is based on survey data obtained from a questionnaire distributed to 23,500 individuals in 2016. In Italy, student enrolment in a Ph.D. involves a university-based selection process; most students then receive eithe
Extracorporeal membrane oxygenation (ECMO) is a last resort therapy for patients with respiratory failure where the gas exchange capacity of the lung is compromised. Venous blood is pumped through an oxygenation unit outside of the body where oxygen diffusion into the blood takes place in parallel to carbon dioxide removal. ECMO is an expensive therapy which requires special expertise to perform.
The hippocampus is a primary region affected in Alzheimer's disease (AD). Because AD postmortem brain tissue is not available prior to symptomatic stage, we lack understanding of early cellular pathogenic mechanisms. To address this issue, we examined the cellular origin and progression of AD pathogenesis by comparing patient-based model systems including iPSC-derived brain cells transplanted into
Traditionally, alkaline water electrolysis (AWE) uses diaphragms to separate anode and cathode and is operated with 5–7 M KOH feed solutions. The ban of asbestos diaphragms led to the development of polymeric diaphragms, which are now the state of the art material. A promising alternative is the ion solvating membrane. Recent developments show that high conductivities can also be obtained in
Aging exerts profound effects on the hematopoietic system, leading to a loss of homeostatic control and reduced regenerative capacity. Clinical consequences of these changes include anemia, compromised immune function and an increased prevalence of myeloid disorders among the elderlies. A growing body of evidence suggests that defects at the stem and progenitor cell levels contribute to many of th
Catalytic processes are present in a wide range of aspects, from fundamental biological processes to modern chemical synthesis. In practical terms, catalysis has thrived as a rapidly growing industry. However, a significant gap in our understanding of catalytic processes exists between the molecular and industrial scales, arising from the complexity at the nano- and micro-levels of catalytic nanop
We will give a short introduction to foreground/background estimation and Hidden Markov fortracking. More information about the topics can be found in the papers listed at the end.
