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Approximately a quarter of a million women are diagnosed with ovarian cancer annually worldwide. Identifying the genes involved may ultimately lead to the development of corrective and preventive measures to fight this type of cancer. Next Generation Sequencing is a technology that can reveal the genes central to cancer initiation and development, however the analysis of the data is problematic du
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This thesis explores the experience of being young, Egyptian, supportive of the 2011 revolution, and active in civil society in the post-revolutionary period in Cairo and Alexandria. It draws from 5 in-depth interviews, and aims to understand the reasons behind youth’s engagement in the revolution beyond the framework of youth economic exclusion. It looks into their expectations from the revolutio
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Recent findings support the hypothesis that inhibition of SMYD3 methyltransferase may be a therapeutic avenue for some of the deadliest cancer types. Herein, active site-selective covalent SMYD3 inhibitors were designed by introducing an appropriate reactive cysteine trap into reversible first-generation SMYD3 inhibitors. The 4-aminopiperidine derivative EM127 (11C) bearing a 2-chloroethanoyl grou
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Objectives.: To assess the comparability of the Tandem-R and IMx serumprostate-specific antigen (PSA) assays across levels of the ratio of free-to-total serum PSA found in a community-based population of healthy men. Methods.: Banked serum samples from the baseline component of the Olmsted CountyStudy of Urinary Symptoms and Health Status Among Men were thawed and analyzed using the Tandem-R and I
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Education reduces the intergenerational transfer of poverty and boosts growth according to the Social Investment (SI) approach (Morel, Palier, and Palme 2011). However, educational systems differ in their capacity to promote equality and produce the skills needed in today‘s knowledge economies. Despite extensive scholarship on how education policies vary in terms of their social and economic effec
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Employer branding in organizational human resources management is essential. Nevertheless, certain gaps persist within the realm of scientific research in this field, particularly in the exploration of novel concepts like employer brand personality appeal and its potential impact within the hospitality industry, which grapples with numerous human resources challenges. To fill this gap in knowledge
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The accumulation of senescent cells drives inflammaging and increases morbidity of chronic inflammatory lung diseases. Immune responses are built upon dynamic changes in cell metabolism that supply energy and substrates for cell proliferation, differentiation, and activation. Metabolic changes imposed by environmental stress and inflammation on immune cells and tissue microenvironment are thus chi
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The aim of this Masters Thesis was to investigate whether social capital is translated into performance by the Community Based Organizations (CBOs) to reach collective goals for the development of the community in rural Bangladesh. Both qualitative and quantitative methods were used in this study. This research was carried out in eight villages of Bangladesh and two hundred households were surveye
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Abstract The integration of Muslim immigrants into the European societal sphere has have recently received the utmost concern of Europeans. This is because Muslim status has changed from ?immigrant? to ?threat? or ?challenge? to peace and prosperity of Europe in the aftermath of 9/11 attacks. Muslim exclusion from social life is now a problem necessitating an urgent solution. At this point, this
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Here, we present a revised protocol to derive neuroepithelial stem (NES) cells from human induced pluripotent stem cells. NES cells can be further differentiated into a culture of neurons (90%) and glia (10%). We describe how to derive and maintain NES cells in culture and how to differentiate them. In addition, we show the potential use of NES cells to study the role of reactive oxygen species in
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A meshless collocation method based on radial basis function (RBF) interpolation is presented for the numerical solution of Maxwell's equations. RBFs have attractive properties such as theoretical exponential convergence for increasingly dense node distributions. Although the primary interest resides in the time domain, an eigenvalue solver is used in this paper to investigate convergence properti
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The events on September 11, 2001, changed the view for many regarding the use of force. The US immediately engaged in a war against terrorism, and in an attempt to win this war and protect American citizens, President Bush and his administration used all means necessary. Thus, the Bush Doctrine came to be. This doctrine introduced a controversial view of the use of force. It would allow the US to
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The purpose of the study was to capture a number of views on what impact language has on integration processes and social life. Since language is an important component of communication amongst people, it affects several aspects of everyday life such as occupation and social participation. To accomplish the aim eight people of foreign origin with experience of studying the language education progr
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Water resources management has been reconfigured over time and space; as power over decision-making processes has increasingly been vested from the state and distributed among networks of private and non-governmental actors. Geographical scholarships of environmental governance seek to critically analyse this transformation in order to grasp how decisions are made, and the consequences that entail
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Phenological vegetation characteristics are valuable inputs to several ecosystem-related models: including carbon exchange and climate change. Phenological characteristics are effective measures of changes in vegetation in an area and are subject to the seasonal and inter-annual climatic variations. In arid and semi-arid ecosystems, precipitation is the main driving factor for changes in vegetatio
