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We are on a hunt for the invisible in this second episode of the third season of The Meridian. Ruth Pöttgen is a senior lecturer at the Department of Physics where she is studying fundamental particles. She is especially interested in finding that mysterious and elusive Dark Matter particle.In this third season we are also including some Cosmic Curiosities. These are some ideas, events or trivia

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Decarbonization policies require public support to be implemented and to remain in legislation. Examinations of public support for climate policies tend to focus on asmall number of policy instruments and/or use hypothetical instead of real policy proposals. Here, we address these criticisms by examining public support acrossfour distinct policy instruments– command-and-control, market-based, info

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This study bridges occupational health and innovation management by proposing psychosocial safety climate (PSC) as a key precondition for employee-driven innovation (EDI). EDI emphasises employees’ unique potential to generate and implement innovative ideas, with conducive working conditions, particularly those supporting psychological health, being crucial. Using a mixed-method explanatory design

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This article addresses the issue of how Social Science and Humanities (SSH) researchers frame and argue relevance, where there are no explicit expectations to do so. It uses research project reports submitted to a Swedish research council, to distil and further analyze ‘relevance expressions’. These expressions illustrate some methodological differences along the lines of the long-standing distinc

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This article investigates the performance of several residuals for the Cox proportional hazards regression model to diagnose the influential observations. The standardized and adjusted forms of residuals are proposed for Cox proportional hazards regression model. In addition, Cook’s distance is proposed for both standardized and adjusted residuals. The assessment of different residuals for the ide

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High-pressure homogenizers are prone to cavitation, which causes wear and influences breakup efficiency. However, the inception point, as well as the extent and intensity, depends on geometry, operation, and fluid properties. While several methods have been previously suggested to characterize cavitation in homogenizer valves (including ultrasonic methods), they have required highly specialized, s

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The curve number (CN) method, developed by the Natural Resources Conservation Service (NRCS), is one of the most widely used approaches worldwide to estimate runoff from rainfall events. However, one of the remaining uncertainties in the method remains whether to apply a frequency-matched or natural data approach for computing the CN from rainfall-runoff data. To address this knowledge gap, this s

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Proteins and peptides are vital biomolecules, and deuterated amino acids are increasingly applied in areas such as drug discovery, metabolic tracing, and neutron scattering studies. In this study, we performed deuteration on all 20 proteinogenic amino acids, including their side chains, and established efficient methods for 13 amino acids. Using a Pt/C-catalyzed hydrogen–deuterium exchange reactio

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The retinoblastoma gene (RB1), which is located on chromosome 13q14.2, is mutated in retinoblastoma (RB), the most common malignant intraocular tumor in children. About 8000 new cases of retinoblastoma are diagnosed globally each year, accounting for approximately 1 in 17,000 live births. RB is prototypically considered hereditary by nature as thirty to forty percent of cases have autosomal domina

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The Cherenkov Telescope Array (CTA) is the future observatory for ground-based imaging atmospheric Cherenkov telescopes. Each telescope will provide a snapshot of gamma-ray induced particle showers by capturing the induced Cherenkov emission at ground level. The simulation of such events provides camera images that can be used as training data for convolutional neural networks (CNNs) to differenti

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Dopaminergic neurons in the ventral midbrain are critical for regulating movement, cognition, and emotion. Ventral midbrain organoids can be used to model both development and diseases of the dopaminergic system, especially Parkinson’s disease. Here, we summarize recent advances and remaining challenges in developing such three-dimensional organoids from human pluripotent stem cells. We outline ho

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The establishment of innovation ecosystems has become an increasingly prevalent strategy for fostering territorial, economic and social development. However, the existing literature provides limited insights into the strategic conditions that enable the emergence of such ecosystems. This paper addresses this gap by identifying the critical elements and mechanisms underpinning their creation. Speci

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To address environmental and climate issues, alternative technologies to fossil resources are sought after, both for the production of fuels and of chemicals. Algae appear as an attractive solution and have applications in the food, feed, energy or chemistry at large. A study funded by ADEME and conducted by ENEA, a consulting firm for energy and sustainable development for the industrial sector,

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Universities are expected to play a proactive role in the sustainable development andtransformation of their regions. However, they face external and internal barriers toplay that role. One possible approach to overcome those barriers is through trans-formative academic institutions (TAIs). TAIs are defined as research centres createdwithin universities to proactively engage in territorial develop

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This paper presents a methodology to fully characterize the dynamic range of a linear X-ray detector, usually employed to perform radiography and tomography. The proposed procedure analyzes each pixel of the detector and presents the results both in terms of general performance of the detector and as a spatial distribution of different parameters for each pixel. This method has been applied to thr

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Critical scholarship has long pointed to the problematic ways in which mainstream International Relations (IR) takes Westphalian state politics to be universally applicable, yet existing analyses fall short of providing an alternative grounding for IR. Departing from the close relationship between medicine and politics, this article advances two arguments. First, Westphalian IR is based on a parti

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Parametric design systems serve as powerful assistive tools in the design process by providing a flexible approach for the generation of a vast number of design alternatives. However, contemporary parametric design systems focus primarily on low-level engineering and structural forms, without an explicit means to also take into account high-level, cognitively motivated people-centred design goals.