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To understand the developmental trajectories in early lymphocyte differentiation, we identified differentially expressed surface markers on lineage-negative lymphoid progenitors (LPs). Single-cell polymerase chain reaction experiments allowed us to link surface marker expression to that of lineage-associated transcription factors (TFs) and identify GFRA2 and BST1 as markers of early B cells. Funct
LED-ljusen har utvecklats i snabb takt under de senaste tio åren och de är idag de ljus som är mest attraktiva för många köpare. Det som gör dem så attraktiva är främst deras höga energieffektivitet jämfört med traditionella glödlampor. I linje med hur vi försöker handskas med klimatförändringarna och alla de hotbilder för människor och natur som denna utveckling förknippas med, så behöver vi ta t
Clinical trials examining insulin-like growth factor-I receptor (IGF1R)-targeting strategies have emphasized that better predictive biomarkers are required to improve patient selection. Immunohistochemical tumor-specific protein expression of IGF1R, insulin receptor (InsR), and phosphorylated IGF1R/InsR (pIGF1R/InsR) individually and combined in relation to breast cancer prognosis was evaluated in
Objectives. To compare the correspondence of discharges and diagnoses between medical records and an administrative database in diabetic patients with foot ulcers and to calculate inpatient costs from the different sources. Design. Discharge data from 117 prospectively followed patients were compared with information from the Swedish Inpatient Registry during the same treatment period for each pat
BACKGROUND: Spatial epidemiological analyses primarily depend on spatially-indexed medical records. Some countries have devised ways of capturing patient-specific spatial details using ZIP codes, postcodes or personal numbers, which are geocoded. However, for most resource-constrained African countries, the absence of a means to capture patient resident location as well as inexistence of spatial d
Objective: To compare the effectiveness of education (ED) plus home exercise (HE) and ED plus supervised exercise (SE) according to information provided by the Better Management of Patients With Osteoarthritis (BOA) Registry, a nationally implemented rehabilitation program for patients with hip and knee osteoarthritis (OA). In addition, we investigated whether or not the effect of the treatments d
I denna uppsats undersöks hur musikkreatörer upplever de förändringar som skett i musikbranschen de senaste tio åren till följd av den tekniska utvecklingen i form av bland annat gratisteknologier och tjänster som Spotify samt fildelning. I undersökningen har kvalitativa metoder i form av intervjuer använts. Vi har utgått från ett antal teoretiska begrepp som exempelvis medielogik, mediekonvergens
I denna uppsats undersöks hur musiker upplever de förändringar som skett i musikbranschen de senaste tio åren till följd av den tekniska utvecklingen i form av bland annat gratisteknologier, exempelvis Spotify och Myspace, samt fildelning. I undersökningen har kvalitativa metoder i form av intervjuer använts. Vi har utgått från ett antal teoretiska begrepp som exempelvis medielogik, mediekonvergen
Syftet med detta arbete är att undersöka diskussionen kring testamentsregister i Sverige. Den deskriptiva delen av arbetet inriktar sig främst på varför Sverige saknar ett nationellt testamentsregister och vilka argument som har framförts för och emot ett sådant. För att ytterligare belysa frågan behandlas rättsläget för testamentsregister i Danmark och Norge som båda har någon form av testamentsrThe aim of this thesis is to discuss if registration of wills in Sweden would be possible. The descriptive part focuses mainly on why Sweden does not have a national register of wills and the arguments put forward for and against such a register. To further highlight the issue the register of wills in Denmark and Norway will be dealt with. Both of these countries have different forms of testamenta
Att uppskatta lövyteindex med satellitdata Vegetation har unika spektrala egenskaper som kan användas inom fjärranalys för att få information om viktiga ekologiska parametrar, som t.ex löyteindex (eng. leaf area index, LAI, lövyta per markenhet). LAI styr många ekologiska processer som fotosyntes och transpiration. Med hjälp av satellitbilder kan man uppskatta LAI i stor skala. Vegetation absorLeaf area index, LAI, is an important biophysical parameter in ecological modeling. It is the ratio of leaf area per unit ground area. To obtain LAI over large areas in a fast and convenient way the use of satellite data is important. Aim of the project was to determine if there is a relationship between LAI and red-, NIR reflectance and a couple of vegetation indices: Global Environment Monitorin
Svensk populärvetenskaplig sammanfattning Fjärranalys av skogsskövling längs med den trans-amzoniska motorvägen Skogsskövling är ett av de större miljöproblemen vi har idag. Speciellt snabb har skövlingen varit i Amazonas regnskog, där minst tjugo procent försvunnit de senaste 40 åren. Fjärranalys används för att uppskatta skogsskövling längs med den transamazoniska motorvägen (BR230). Analysen utDeforestation is one of the biggest environmental challenges today. Especially severe has the deforestation of the Amazon rainforest been where at least 20% has been cleared the last 40 years. A time series analysis of deforestation rates between 1984 and 2013 has been performed on several sites close to the Trans-Amazonian highway BR230 in the Amazon and Para states. This is done by applying a su
Despite a large number of studies, out of all drivers of radiative forcing, the effect of aerosols has the largest uncertainty in global climate model radiative forcing estimates. There have been studies of aerosol optical properties in climate models, but the effects of particle number size distribution need a more thorough inspection. We investigated the trends and seasonality of particle number
Hematopoietic stem cells (HSCs) are rare cells on top of the differentiation hierarchy of hematopoiesis. HSCs are unique in their combined capacity to differentiate into all mature blood lineages and self-renew to maintain the HSC pool. Based on classical models of hematopoiesis in mouse, the self-renewal potential of HSCs is gradually and step-wise lost during the transition from long term (LT)-H
As production and supply chains rely on exploitative extraction of nature and labour, consumption levels (resource use) remain one of the main indicators of inequality, across and within national contexts. In times of ongoing climate crisis and rising levels of inequalities, welfare systems face the dual challenge of transforming economies to reduce their reliance on unsustainable industries as we
INTRODUCTION: Streptococcus pneumoniae (the pneumococcus) effectively colonizes the human nasopharynx, but can migrate to other host sites, causing infections such as pneumonia and sepsis. Previous studies indicate that pneumococci grown as biofilms have phenotypes of bacteria associated with colonization whereas bacteria released from biofilms in response to changes in the local environment (i.e
In this conceptual paper we reimagine the Capitalocentric present. To do so, we (1) critique corporate fantasies about ethical consumption; (2) offer alternative relational ethics of consumption, with special attention to concrete neo-animist practices to imagine alternative futures to the Capitalocentric present, and (3) invite imaginative theorization as a bridge between present and future.In this conceptual paper we reimagine the Capitalocentric present. To do so, we (1) critique corporate fantasies about ethical consumption; (2) offer alternative relational ethics of consumption, with special attention to concrete neo-animist practices to imagine alternative futures to the Capitalocentric present, and (3) invite imaginative theorization as a bridge between present and future.
Measuring the number concentration of colloidal nanoparticles (NPs) is critical for assessing reproducibility, enabling compliance with regulation, and performing risk assessments of NP-enabled products. For nanomedicines, their number concentration directly relates to their dose. However, the lack of relevant reference materials and established traceable measurement approaches make the validation
