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BACKGROUND: We aimed to identify the target of deprescribing, i.e. the 24-hour SBP increase needed to achieve the greatest reduction of SBP drops.METHOD: Forty hypertensive patients (mean age 73.6 ± 9.3 years, 26 females) with reflex syncope and SBP drops on a screening ABPM were advised to withdraw or to reduce their therapy. The study objective was the reduction of SBP drops <90 mmHg and <100 mm

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This report aims to identify both barriers that hinder energy-efficient renovation of buildings and drivers enabling the implementation of energy and cost-effective renovation of buildings and energy supply systems at the district level.Fifteen success stories regarding barriers and drivers were analysed in the first step. These success stories consisted of projects from seven European countries (

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The occurrence of within-population variation in germination behavior and associated traits such as seed size has long fascinated evolutionary ecologists. In annuals, unpredictable environments are known to select for bet-hedging strategies causing variation in dormancy duration and germination strategies. Variation in germination timing and associated traits is also commonly observed in perennial

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A continuum damage framework is proposed for modelling the delamination process occurring in paperboard during mechanical loading. The main application of interest is line creasing and subsequent line folding used in package forming. To adequately capture creasing and folding, a continuum damage framework that uses a single isotropic damage variable that evolves with the plastic strains associated

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Planning of neighborhoods that efficiently implement active solar systems (e.g., solar thermal technologies, photovoltaics) and passive solar strategies (e.g., daylight control, sunlight access through optimized buildings' morphology, cool pavements, greeneries) is increasingly important to achieve positive energy and carbon neutrality targets, as well as to create livable urban spaces. In that re

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Cardiac magnetic resonance (CMR) is the gold standard noninvasive imaging modality to assess tissue characteristics in vivo which gives it a unique advantage in discriminating benign cardiac masses from malignant tumors. CMR also provides visualization of tumor invasion, hemodynamic effects, and location relative to surrounding cardiac and extracardiac structures. These features make CMR an essent

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Fire has the potential to create significant impacts on the built environment. Managing this impact is sometimes pursued without consideration of the interface between the natural and technological worlds. However, as society has recognized the impacts of technological development on environmental sustainability, the need for sustainable and resilient development has emerged. To facilitate sustain

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Background: Most strokes and cardiovascular diseases (CVDs) are potentially preventable if their risk factors are identified and well controlled. Digital platforms, such as the PreventS-MD web app (PreventS-MD) may aid health care professionals (HCPs) in assessing and managing risk factors and promoting lifestyle changes for their patients. Methods: This is a mixed-methods cross-sectional two-phas

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Lifetimes of high-spin states have been measured for 142Gd and 134Nd with EU-ROBALL IV and AFRODITE, respectively, using DSAM. From calculations in the cranked Nilsson-Strutinsky model it was concluded that at the high-spin states of the (+,0)1 band, 142Gd represents a triaxial nucleus rotating around the longest principal axis.

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We survey the current state of the art in the use of nonparametric methods to test separability. We focus on three tests: Swofford and Whitney's (1994) joint test of the necessary and sufficient conditions for weak separability; Fleissig and Whitney's (2003) sequential test of those conditions; and Jones and Stracca's (2006) test of the necessary and sufficient conditions for additive separability

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Finite Element (FE) model updating is crucial for identifying key parameters in structural design and improving predictive accuracy. Despite extensive research on advanced FE procedures approved for user applications, persistent disparities remain in real-world scenarios, especially for complex materials like wood. Capturing accurate mechanical characteristics with traditional models poses challen

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The study of rapid and stochastic events that involve multiple species, such as chemical reactions and plasma dynamics, requires means to capture multispectral information in two dimensions at both high temporal- and spatial resolution. Commercially available cameras that provide high temporal resolution are based on either signal intensification or rapid data acquisition. Intensified cameras prov

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The minimization of the total variation is a well-established technique of preservingedges and discontinuities. Therefore it has wide applicability in image processing,where one is interested in recovering a corrupted image while preserving edges inthe image. In the last decades, in the literature, there have been introduced manydifferent approaches and algorithms for minimizing the total variatio

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When treating pregnant women with antiepileptic drugs (AEDs), clinicians have to balance potential fetal adverse effects against the risks of uncontrolled maternal disease. Only recently have emerging scientic data provided a rational basis for treatment decisions considering both aspects. The focus of research is currently moving from the first to the second AED generation. Lamotrigine is relativ

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Aims Short-term ambulatory electrocardiogram (ECG) monitoring is often used to assess premature atrial complex (PAC) and premature ventricular complex (PVC) frequency, but the diagnostic reliability is unknown. The objective of this study was to study the day-to-day variability of PAC and PVC frequency. Methods We used 14-day full-disclosure mobile cardiac telemetry recordings without atrial fibri

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Non-technical summaryBrazil – one of the world's largest biocultural diversities – faces high rates of habitat loss, social inequality, and land conflicts impacting indigenous and local peoples. To challenge that, Brazilian sustainability science and education needs to be strengthened. We searched for elements in ongoing bottom-up sustainability social movements that can help serve that purpose. W