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This theoretical paper adopts a procedural perspective to identify the challenges associated with the implementation of the full scope of approaches to circular public procurement (CPP). We contend that beyond considering CPP from a substantive standpoint (i.e. the procurement affects outside of the organization), adopting a procedural perspective (i.e. the procurement affects inside an organizati
Introduction: Rimegepant is an oral small-molecule calcitonin gene-related peptide receptor antagonist approved in several countries for acute treatment of migraine and preventive treatment of episodic migraine in adults. This review summarizes the evidence, published to date, for the use of rimegepant as an acute or preventive treatment of migraine. Areas covered: A brief overview of migraine, th
Recently, the incentive structure facing doctoral students and researchers in economics has changed significantly in many European countries as a result of the adoption of the US approach to evaluating research output. This poses a threat to the development and position of the subject of economics in Europe since evaluation for promotion is characterised by an excessive focus on publishing in the
Considering the Islamic perspective on forced migration and displacement, along with the conceptual framework of Islamic social welfare instruments as tools for wealth redistribution to support those in need, this study explores the potential complementarity between Islamic and conventional financing in addressing refugees' basic needs and economic empowerment. Specifically, this research examines
The search for drugs that modulate NMDA receptors has been very active in the latest decades since they play a pivotal role in neuronal death and in several neurological conditions, including stroke, traumatic brain injury, and neurodegenerative diseases. Activating the receptor evokes an entry of calcium into the neuron, thus leading to a rapid depolarization that can be measured using electrophy
BACKGROUND: The diagnostic role of signal-averaged ECG (SAECG) in arrhythmogenic right ventricular cardiomyopathy (ARVC) has lately been questioned. We assessed the value of SAECG-derived late ventricular potentials (LP) in ARVC diagnosis and its association with disease manifestations.METHODS AND RESULTS: Patients with definite ARVC diagnosis or genotype-positive family members who underwent SAEC
The physiological mechanism for producing antigen-specific antibodies is based on a two-phase neo-Darwinian process: the first phase consists of diversity generation (formation of the repertoire), and the second phase is antigen-mediated selection. In this article, we consider how the natural immunoglobulin gene-diversification processes can be exploited both in vivo and in vitro in order to allow
Background: Apnea of prematurity is a common problem in preterm infants that may have significant consequences on their development. Methylxanthines (aminophylline, theophylline, and caffeine) are effective in the treatment of apnea of prematurity. Doxapram is used as a respiratory stimulant in cases refractory to the methylxanthine treatment. Objectives: To evaluate the benefits and harms of doxa
Microbial contaminants are responsible for several infectious diseases, and they have been introduced as important potential food- and water-borne risk factors. They become a global burden due to their health and safety threats. In addition, their tendency to undergo mutations that result in antimicrobial resistance makes them difficult to treat. In this respect, rapid and reliable detection of mi
This chapter brings the Global South to the centre stage of degrowth debates to envision what a truly global and anti-colonial movement towards degrowth could look like. To do so, we first bring the varying definitions of the term ‘Global South’ to the forefront and consider the Global South not as an undynamic and apolitical cate- gory, but as a site of resistance and independent critical thinkin
The discussion on the Anthropocene has increased the urgency to promote a sustainable society, considering the planetary boundaries, population growth and resource scarcity. Thus, the United Nations created the 2030 Agenda for Sustainable Development to address this challenge, including 17 Sustainable Development Goals (SDGs) and 169 SDG targets. In this context, the energy sector is one of the ma
The flavour-tagging algorithms developed by the ATLAS Collaboration and used to analyse its dataset of s=13 TeV pp collisions from Run 2 of the Large Hadron Collider are presented. These new tagging algorithms are based on recurrent and deep neural networks, and their performance is evaluated in simulated collision events. These developments yield considerable improvements over previous jet-flavou
Performance of a proton exchange membrane (PEM) fuel cell is very sensitive to its electric resistance appearing in its functional components. In this paper, the electric resistance as well as related parameters of a cell is evaluated by a recently developed numerical method in the through-plane direction of the electrodes. The results show that the channel/rib structure leads to non-homogeneous e
BACKGROUND: Perinatal stroke refers to a diverse but specific group of cerebrovascular diseases that occur between 20 weeks of fetal life and 28 days of postnatal life. Acute treatment options for perinatal stroke are limited supportive care, such as controlling hypoglycemia and seizures. Stem cell-based therapies offer a potential therapeutic approach to repair, restore, or regenerate injured bra
The cooperative emission of interacting nanocrystals is an exciting topic fueled by recent reports of superfluorescence and superradiance in assemblies of perovskite nanocubes. Several studies estimated that coherent coupling is localized to a small fraction of nanocrystals (10−7-10−3) within the assembly, raising questions about the origins of localization and ways to overcome it. In this work, w
Previous research has identified good communication as one of several key factors essential for destination resilience. However, there has been a lack of research on how communication contributes to this development. To address this gap, this study explores the communication work done by Destination Management Organizations (DMOs) with stakeholders to influence destination resilience. The study ex
The Cherenkov Telescope Array (CTA) will be the next generation ground-based observatory for very-high-energy (VHE) gamma-ray astronomy, with the deployment of tens of highly sensitive and fast-reacting Cherenkov telescopes. It will cover a wide energy range (20 GeV - 300 TeV) with unprecedented sensitivity. To maximize the scientific return, the observatory will be provided with an online softwar
Introduction: With the rapid development of treatment modalities for obesity management, there is a growing need for guidelines. This was acknowledged by the Swedish National Board of Health and Welfare and in 2020 the process of producing the first national guidelines for obesity care, including both children and adults, was initiated. The main aim was to ensure equal high standard care throughou
Here, we present new models to fit small angle X-ray scattering (SAXS) data for the characterization of ion tracks in polymers. Ion tracks in polyethylene terephthalate (PET), polycarbonate (PC), polyimide (PI) and polymethyl methacrylate (PMMA) were created by swift heavy ion irradiation using 197Au and 238U with energies between 185 MeV and 2.0 GeV. Transmission SAXS measurements were performe
