Filtyp
In the present work, we describe the design, synthesis, and evaluation of a galectin-8- binding fluorescent probe designed for a competitive fluorescence polarization (FP) assay for screening new galectin-8N inhibitors. The probe was characterized for its photophysical properties and its binding affinity for galectin-8N was determined by using FP. We evaluated the probe in a competitive FP assay w
Budburst models have mainly been developed to capture the processes of individual trees, and vary in their complexity and plant physiological realism. We evaluated how well eleven models capture the variation in budburst of birch and Norway spruce in Germany, Austria, the United Kingdom and Finland. The comparison was based on the models performance in relation to their underlying physiological as
IgA nephropathy (IgAN) is characterized by mesangial cell proliferation and extracellular matrix expansion associated with immune deposits consisting of galactose-deficient polymeric IgA1 and C3. We have previously shown that IgA-binding regions of streptococcal M proteins colocalize with IgA in mesangial immune deposits in patients with IgAN. In the present study, the IgA-binding M4 protein from
This study examines whether neighbourhood deprivation increases the risk of hospitalization for childhood asthma, after accounting for individual-level maternal socio-demographic characteristics.
Mass and angular distributions of dijets produced in LHC proton-proton collisions at a centre-of-mass energy root s = 7TeV have been studied with the ATLAS detector using the full 2011 data set with an integrated luminosity of 4.8 fb(-1). Dijet masses up to similar to 4.0TeV have been probed. No resonance-like features have been observed in the dijet mass spectrum, and all angular distributions ar
Osteoporosis is a widespread problem afflicting millions of people. Drynol Cibotinis is a newly developed proprietary botanical combination of eight botanicals including Angelica sinensis, Glycine max, Wild yam, Ligustrum lucidum, Astragalus membranaceus, Cuscuta chinensis, Psoraleae corylifoliae, and Drynaria fortune. Each of the botanicals has been used in traditional Chinese medicine to treat o
The so-called capitalist crisis of care has been theorized starting since the 80s. It has been and explored by two literature streams: the ‘feminist’ and the ‘mainstream’. New social and economic challenges in relation to welfare state systems trigger the interest of scholars and policy makers who are looking for sustainable responses to care needs. Welfare states have been repeatedly grouped into
Insects have been recommended by the FAO as a sustainable food alternative to meat. Despite their nutritional quality and sustainability, most Western countries still see insects as belonging far away from the dinner table. Although still a niche market, Denmark has been at the forefront of innovation and adoption of edible insects. I used integral theory to map out the structural, cultural and pe
Here a lung-on-a-chip device was developed and fabricated using 3D-printing of molds. The lung-on-a-chip device was used as a lung injury model by overstretching of murine lung epithelial cells (MLE-12) monolayers, resembling the injury during mechanical ventilation. The cells were exposed to 25% strain, representing pathological conditions seen in ventilator induced lung injury of patients with
This research addresses the potential of political comedy and satire as television genres in the construction of democracy and civic culture in Colombia. Through a set of elite interviews with representative individuals in the media, political humor and media scholarship circles of the country; and through genre-based and political, economical and cultural analyses, this research underscores the r
Although Global Digital Elevation Models (GDEMs) are widely used, their spatial error distributions over extensive regions remain insufficiently understood. Using ICESat-2 Reference Control Points (RCPs) (~ 30 points/km²), this paper not only evaluates GDEMs with point-based metrics such as Root Mean Square Error (RMSE) and Mean Error (ME), but also proposes a novel raster-independent Spatial Erro
Efficient and robust control strategies can greatly contribute to the reliability of fuel cell systems, and a stable output voltage is a key criterion for evaluating a fuel cell system's reliability as a power source. In this study, a polymer electrolyte fuel cell (PEFC) system model is developed, and its performances under different operating conditions are studied. Then two different novel contr
This thesis aims to test and evaluate the use of image-based 3D modelling techniques on rune stones. To test the method a well-documented rune stone was chosen, Hyby stone 1. The stone has been dated to the Viking Age and contains 37 runes, whereof 29 are still visible, two crosses and a stag. These carvings have been detected by other scholars with the use of non-digital methods. In order to eval
Problem definition: Supply chain segmentation is a topic which in later years has received increasing attention from supply chain managers of companies in industrial settings. To members of the supply chain research community the ideas and theoretical contributions underlying the concept of supply chain segmentation are hardly new, but have evolved ever since the beginning of the 1990s. However, a
I svenska domstolar utvecklades under en period av över 30 år en påföljds-praxis i narkotikamål som i hög grad avvek från vad som gäller för andra brottstyper. Straffvärdebedömningen inom området styrdes i princip helt och hållet av tabeller grundade på arten och mängden narkotika. En omfattande praxisomläggning ägde rum åren 2011 till 2013. Omläggningen medförde att samtliga relevanta omständigheIn Swedish courts, over a period of more than 30 years, a practice of punishment was developed in drug cases, which largely differed from those of other types of crime. The penal value assessment in the area was basically governed entirely by tables based on the art and amount of drugs. A comprehensive practice review took place between 2011 and 2013. The conclusion was that all relevant circumsta
Striving to contribute to research on child- and youth spirituality and African theology with a contextually grounded, non-western, qualitative youth perspective, the aim of this study is to seek an understanding of the spirituality of male youth that live on the streets in Nairobi. To fulfil this aim, the research task carried out is an analysis of the source material from six focus group intervi
This thesis aims to investigate the results of the Nordic Swan label on mutual fund flows. As consumers starts to increasingly demand more sustainable investment alternatives, the fund distributers have subsequently started investigating new products with focus on sustainability. In October 2017, the Nordic Swan labelled their first funds containing 25 specific sustainability criteria. The funds s
The occurrence of climate change will have a significant impact on society and adapting to a more sustainable environment is of key importance. The dangers of climate change will include temperature and precipitation patterns becoming more extreme creating a substantial impact on society. Greece’s location and climate make it particularly vulnerable to a changing climate and climate impact assessm
