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Protein S deficiency is a known risk factor for thrombosis. The coexistence of phenotypic type I (reduction in total and free antigen) and type III (reduction in free antigen only) protein S deficiencies in 14 of 18 families was recently reported. We investigated the cause of this phenotypic variation in the largest of these families (122 family members, including 44 affected individuals) using bo

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OBJECTIVE: To compare the capacity of transvaginal Doppler ultrasound examination with that of gray scale sonography as an aid in distinguishing benign and malignant pelvic tumors of suspected adnexal origin. STUDY DESIGN: One hundred and fifty-one women scheduled for laparotomy or laparoscopic surgery because of a pelvic mass of suspected adnexal origin underwent ultrasound examination including

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Background Combined oral contraceptives are classified by the International Agency for Research on Cancer as a cause of cervical cancer. As the incidence of cervical cancer increases with age, the public-health implications of this association depend largely on the persistence of effects long after use of oral contraceptives has ceased. Information from 24 studies worldwide is pooled here to inves

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Aims/hypothesis. Fat accumulation in the liver has been shown to be closely correlated with hepatic insulin resistance and features of insulin resistance, also independently of body weight. It remains to be established how fat in the liver correlates with that in other depots, and whether any association differs between men and women. Methods. Liver fat (assessed using proton spectroscopy), intra-

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Solid fuel fired fluidized bed (FB) boilers are common in combined heat and power (CHP) plants in district heating- and process industry. In this study, utilization of such FB boilers for production of syngas in dual fluidized bed gasifiers and subsequent catalytic biofuel production to substitute natural gas (SNG), methanol (MeOH) and Fischer-Tropsch fuel (FT) has been examined. Based on the hypo

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By testing theories from the likes of Seymour Martin Lipset and Francis Fukuyama, this thesis aims to illuminate the correlations between the size of a nation’s middle class and the stability and rigor of its democracy. Using quantitative data on democracy and middle class size in the time surrounding the financial crisis of 2008-2010, this thesis illustrates the parallel declines in both democrac

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Research suggests that polyphenols, such as anthocyanins, that are found in considerable amounts in many types of berries, contributes with a positive effect on human cognition. However, clinical trials are warranted to support these findings. Preparation for such a trial includes developing a berry-rich study product and a corresponding reference beverage. Phenolic compounds are highly unstable a

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BACKGROUND: Changes in glycosylation of serum proteins are common, and various glycoforms are being explored as biomarkers in cancer and inflammation. We recently showed that glycoforms detected by endogenous galectins not only provide potential biomarkers, but also have different functions when they encounter galectins in tissue cells. Now we have explored the use of a combination of two galectin

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Family caregivers in palliative care have a need for knowledge and support from health professionals, resulting in the need for educational and supportive interventions. However, research has mainly focused on the experiences of family caregivers taking part in interventions. To gain an increased understanding of complex interventions, it is necessary to integrate the perspectives of health profes

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Knowledge about the need for care of elderly individuals in community dwellings and the factors affecting their needs and support is limited. The aim of this study was to characterize the frailty of a population of elderly individuals living in community dwellings in Sweden in relation to co-morbidity, use of drugs, and risk of severe conditions such as malnutrition, pressure ulcers, and falls. In

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The intensification of forest management over the recent decades, in combination with the effects of a warming climate, leaves forestry and forest management with the challenging task of maintaining forest ecosystems’ further abilities to provide ecosystem services. By systematically reviewing peer- reviewed academic literature this study analyzes the concept of multifunctionality and its applicat

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The thesis explores the interaction between patent rights for Standard Essential Patents(SEP) and competition law, particularly Article 102 of the Treaty on the Functioning of the European Union(TFEU), within the context of the European Union(EU) , and compares this interaction with the relevant provisions in the proposed EU SEP regulation COM(2023)232. Three research questions will be discussed:

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The steel industry is one of the most polluting industries globally. There exists an EU waste shipment proposal that aims to restrict the EU export of waste in order to raise safe, environmental standards and circularity within the EU. Under this proposal, steel scrap is defined as waste and since the EU is the largest exporter of steel scrap globally, this has implications for the EU steel indust

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Using the protection for exporters theory the thesis analyzes the EU’s quest for world markets in the case of trade negotiations with Singapore. The protection for exporters theory assumes governments to shift bias from the import competing sector to the export competing sector when exporters are exposed to potential losses. The thesis concludes three main findings of why the EU shifted policy tow

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The global pandemic of Covid-19 has drastically changed the behaviour of citizens around the world. This research aims to identify actions that ensure low-carbon, inclusive forms of mobility that respond to the behavioural changes during Covid-19. The city of Hamburg, Germany, and its problems with transport-related emissions and socio-economic inequalities serve as a representative case study. Th

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Purpose: Positron emission tomography (PET) is increasingly used in neuro-oncology. However, little is known about its application across European institutions and reasons for variable implementation. Methods: Between June and August 2024, members of the European Organisation for Research and Treatment of Cancer - Brain Tumour Group (EORTC-BTG) completed a cross-sectional online survey on PET use

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Objective: The European Society for Vascular Surgery (ESVS) has developed clinical practice guidelines for thecare of patients with diseases of the mesenteric and renal arteries and veins, in succession to the first 2017guidelines, with the aim of assisting physicians and patients in selecting the best management strategy.Methods: These guidelines are based on scientific evidence and expert opinio

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BACKGROUND: Effective T-cell depletion is a prerequisite for haploidentical peripheral blood progenitor cell (PBPC) transplantation. This study was performed to investigate the performance of magnetic cell sorting–based direct large-scale T-cell depletion, which is an attractive alternative to standard PBPC enrichment procedures. STUDY DESIGN AND METHODS: PBPCs were harvested from 11 human leukoc

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Water is arguably the world’s most valuable endangered resource, the management of which has been subject of contentious debate that in recent years has gained growing political, economic and media attention. This study intends to make use of that momentum by constructing a framework for quantifying global water crisis risk that is applied to assess both the EU’s share of such risk and the success