Sökresultat

Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen i världen bland kvinnor och bara i Sverige insjuknar varje år runt 7000 personer. Vi vet att omkring 10-15% av fallen troligen beror på ärftliga faktorer och det har under senare tid gjorts stora insatser för att klargöra exakt vilka arvsanlag som har betydelse för utveckling av sjukdomen. Under början av 90-talet identifieradeHereditary breast cancer constitutes a considerable fraction of the total number of breast cancer cases occurring each year. Up until recently very few breast cancer predisposing genes were known, but many new common polymorphisms contributing to increased cancer susceptibility are continuously being identified. This thesis has focused on familial breast cancer and identifying as well as investi

Wireless access technologies such as UMTS with HSPA extensions, WiMAX, and Flash-OFDM and the convergence towards next generation heterogeneous networks enable the realization of always best connected scenarios. As the resulting heterogeneous networks become easier to access and more reliable to depend on, novel telemedicine services such as vehicular emergency applications emerge. Due to their li

Psychiatric, physical and biological aspects of posttraumatic stress disorder (PTSD) may be associated with dysfunctions in several cellular processes including nitric oxide (NO) production. NO is synthesized from arginine in a reaction carried out by NO synthase (NOS) enzymes. The recently introduced "global arginine bioavailability ratio" (GABR; ratio of arginine to [ornithine+ citrulline]) has

Generative product design systems used in the context of mass customization are required to generate diverse solutions quickly and reliably without necessitating modification or tuning during use. When such systems are employed to allow for the mass customization of product form, they must be able to handle mass production and engineering constraints that can be time-consuming to evaluate and diff

Surface temperature in internal combustion engines is of high interest when studying heat losses. Two approaches for retrieving the surface temperatures are thermocouples and Laser Induced Phosphorescence, LIP. This study aims to analyze LIP as a technique for measuring surface temperature in internal combustion engines. The motivation for this study is the need for accurate surface temperatures w

Three theoretical atomic structure projects of interest for the astrophysical community and the lightning industry which are partially finished will be presented. Extensive ab initio calculations of properties of astrophysical interest has been done or are under its way for Ga I, Ga II, Ga III, In II and In III. The aim of the project is to also make calculations for In I, Tl I, Tl II and Tl III.

This paper describes a novel tool for eliciting user requirements early in the design process of mobile applications. The “Mobile Oracle”, as we have called it, is intended to help developers and designers obtain a better understanding of what the user wants at different points in space and time. It is an extension of a lo-fi version of the well-established Wizard of Oz technique, but it also adds

Objectives: To investigate whether changes in complete blood count (CBC) in islet autoantibody positive children with increased genetic risk for type 1 diabetes are associated with oral glucose tolerance tests (OGTT) and HbA1c over time. Methods: The Environmental Determinants of Diabetes in the Young (TEDDY) study follows children with increased risk for type 1 diabetes in the United States, Germ

Background In adults with serious respiratory illness, breathlessness is prevalent and associated with reduced health-related quality of life. The aim of this review was to assess the impact of breathing techniques on breathlessness in adults with serious respiratory illness. Methods Electronic databases were searched to identify randomised controlled trials testing breathing techniques (technique

Background: Percutaneous coronary intervention (PCI) of saphenous vein grafts (SVG) is associated with poor outcomes and is often regarded as inferior to native vessel PCI. We investigated clinical outcomes of SVG-PCI using contemporary drug-eluting stents (DES), in a complete, nationwide population. Methods: The complete Swedish Coronary Angiography and Angioplasty Registry (SCAAR) was used to id

Background: Acute kidney injury (AKI) is a serious complication of out-of-hospital cardiac arrest (OHCA). Post-resuscitation cardiogenic shock (CS) is a key contributing factor. Targeting a higher arterial carbon dioxide tension may affect AKI after OHCA in patients with or without CS. Methods: Pre-planned exploratory study of a multi-national randomised trial comparing targeted mild hypercapnia o

År 2014 startade Region Skåne en basutbildning för alla chefer inom organisationen i Region Skåne. Basutbildningen infördes med anledning av att säkerställa att alla chefer befattade en gemensam grund att utgå ifrån inför kommande ämnesspecifika arbetsuppgifter. Under årens lopp har få utvärderingar utförts vilket har resulterat i att basutbildningens effektivitet i nuläget är av okänd karaktär. •

The main information in DNA is its four-letter sequence that builds up the genetic information and that is traditionally read using sequencing methodologies. DNA can, however, also carry other important information, such as epigenetic marks and DNA damage. This information has recently been visualized along single DNA molecules using fluorescent labels. Quantifying fluorescent labels along DNA is

Titel - Nyttan med RFID i IKEAs försörjningskedja - Ett sätt för IKEA att uppnå spårbarhet. Författare - Sven Morén Jesper Samuelsson Handledare - Mats Johnsson, Universitetslektor vid institutionen för förpackningslogistik, Lunds Tekniska Högskola. Daniel Hellström, Doktorand vid institutionen för förpackningslogistik, Lunds Tekniska Högskola. Allan Dickner, Förpackningschef inom IKEA-koncer

Denna avhandling utvecklar och utvärderar språkbaserade bedömningar som använder artificiell intelligens (AI) för att omvandla öppet språk till kvantitativa indikatorer och beskrivningar av psykiska hälsorelaterade konstruktioner. Medan slutna skalor länge har dominerat psykologiska bedömningar, är de begränsade av fasta svarsformat och kanske inte helt fångar komplexiteten i individers upplevelseThis thesis develops and evaluates language-based assessments that use artificial intelligence (AI) to transform open-ended language into quantitative indicators and descriptions of mental health related constructs. While closed-ended scales have long dominated psychological assessment, they are limited by fixed response formats and may not fully capture the complexity of individuals’ experiences.

Background: Physiologically guided revascularization improves clinical outcomes. The cutoff values for deferral with fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are the same across all coronary arteries, despite differences in coronary flow patterns. The objective was to compare deferral rates using either FFR or iFR in the right coronary artery (RCA), left anterior desce

Background: Previous studies suggest an antidepressant effect of omega-3 fatty acids (n-3 PUFAs). This effect may be larger in patients with low-grade inflammation, defined as mild elevations of high sensitivity C-reactive protein or other commonly used inflammatory markers. The antidepressant mechanisms of n-3 PUFAs are not fully understood but may involve modulation of immunometabolic processes