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INTRODUCTION: Autoantibodies against insulin (IAA) are early appearing markers of autoimmunity against the pancreatic islet beta cells and predict progression to type 1 diabetes if additional islet autoantibodies also develop. It is still controversial if proinsulin rather than insulin is the primary autoantibody.METHODS: The aim of the present study was to compare the half-maximal concentration (

INTRODUCTION: Early detection of Alzheimer's disease (AD) is critical for timely intervention as disease-modifying treatments emerge. Speech-based digital biomarkers offer scalable options for remotely capturing speech-derived functional changes associated with early cognitive decline, but validation across real-world populations remains limited.METHODS: We evaluated the speech biomarker for cogni

In recent years, Sweden has seen an increase in archaeological investigations regarding subaltern settlements from the recent past. This chapter advocates using a triangulation approach with written documents, historical maps, and archaeological data as a preferred method for investigating rural subalterns. This approach enables archaeology to play a significant role in uncovering subaltern multi-

Obesity is a key contributor to heart failure, driving increased morbidity, mortality, and healthcare costs. This association is supported by multiple pathophysiological mechanisms and consistent epidemiological evidence, particularly not only in heart failure with preserved ejection fraction (HFpEF), but also in heart failure with reduced ejection fraction (HFrEF). Given the rising prevalence of

The thesis examines the truth and reconciliation commission in South Africa and its possibilities to act as a vehicle in the process of consolidating democracy. The norms and values that can be found in the principles and practices of the commission are scrutinized, and the means of presenting this norms to the public is also looked into. The issue of how to deal with the human rights violations o

Following the Bosman verdict from the ECJ in 1995, FIFA, the governing body of football, had to change its rules for the status and transfer of players to bring them in line with EC law. With the threat of an outright prohibition decision against the international transfer system under the EC Competition rules, FIFA reached an agreement with the Commission, in March 2001, on the principles for the

This thesis addresses the new policy reform for the establishment of newly arrived refugees in Sweden from a welfare policy perspective. The establishment reform aims to further integration of newly arrived refugees into Swedish society by transferring responsibility from local municipalities to the Public Employment Service and by introducing a private actor in the process. In the thesis I analys

Background Frigoscandia Logistics AB, FSL, was founded in 1997 as a Fourth Party Logistics provider, 4PL, with the purpose to supply temperature-controlled food and other goods to customers world wide. The main purpose is to provide a complete logistics service package including physical, administrative as well as financial flows. Moreover FSL takes the ownership of the products, which is unique.

Det här examensarbetet grundar sig på en översättning av en lättläst barnbok, som i sin tur är baserad på en myt från Snorres Edda. Uppsatsen inleds med en källtextanalys, som i viss mån utgår från Lennart Hellspong och Per Ledins (1997) modell, och som grundas på Göte Klingbergs (1977) teorier om bearbetning och översättning av böcker för barn. Därefter följer en kortare diskussion om övervägande

This thesis looked into the protection and occupational development process under the Thai government shelter and the extent to which it has assisted and supported the victims of human trafficking, both Thai and non-Thai, in psychosocial rehabilitation, therapy, and vocational training and development. I used the capability theory and empowerment approach as a framework of analysis to assess quali

With the post-Kyoto climate negotiations underway, global emissions must be cut by 66% by, 2050 according to the IPCC, to prevent further damage to the environment. In order for this emission cut to be possible, all nations have to be a part of these negotiations. The Kyoto Protocol and the UNFCCC is the natural starting point for a new climate regime that must be established. Through a literatur

To deal with the problems resulting from the current unsustainable pattern of resource utilization, the material life cycle of plastics should be extended. Extended producer responsibility (EPR) has been increasingly adopted as a strategy to redirect the material flow, but its contributions to the market development of recycled plastics have not been well researched. Norway is one of the countrie

The role of environmental permits as a driver for environmental improvements has been a topic of debate for a while. Many permitting regulations were designed in the 1970's and have not been updated since then. Consequently, they have acted mostly as a driver for the adoption of pollution control technologies. Some experts now see that appropriately designed and implemented environmental permi

The Middle Danube (Carpathian) Basin is considered to encompass some of the thickest and most complete records of aeolian dust deposition in Europe, covering the last two glacial–interglacial cycles. In this study, independent, published chronologies based on absolute dating methods were compiled for 34 loess-palaeosol sequences and modelled using Bayesian statistics. Mass accumulation rates (MARs

The book’s aim is to systematize normative assessments of the Court of Justice of the European Union’s decision-making process, defining ‘normative’ as an evaluation based on openly acknowledged, theoretically informed standards that take into account the institutional reality of the Court. This is important because the stakes are very high: the Court is a very influential institution, and the mot

Chrysene-containing polymers functionalized with piperidinium- and quinuclidinium cations, respectively, are prepared by polyhydroxyalkylation and studied as anion exchange membranes (AEMs). Experimental results, supported by theoretical considerations, indicate that the chrysene units significantly enhance alkaline stability; a poly(chrysene piperidinium) AEM shows only 16% total ionic loss, comp