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The clinical correlations and significance of subnormal CD4 levels in HIV-negative patients with TB are unclear. We have determined CD4 cell levels longitudinally during anti-tuberculosis treatment (ATT) in patients, with and without HIV co-infection, and their associations with clinical variables.
Background Lactobacillus reuteri converts glycerol to 3-hydroxypropionic acid (3HP) and 1,3-propanediol (1,3PDO) via 3-hydroxypropionaldehyde (3HPA) as an intermediate using enzymes encoded in its propanediol-utilization (pdu) operon. Since 3HP, 1,3PDO and 3HPA are important building blocks for the bio-based chemical industry, L. reuteri can be an attractive candidate for their production. However
FKBP12 serves a dual role as a peptidyl-prolyl cis-trans isomerase and as a modulator of several cell signaling pathways. The macrolide FK506 is a transition-state analog of the catalyzed reaction and displaces FKBP12 from its natural target proteins. We compared the conformational exchange dynamics of the backbone and methyl-bearing side chains of FKBP12 in the free and FK506-bound states using N
OBJECTIVES: This is the first nationwide study with the aim to analyze whether there is an association between country of birth in first-generation immigrants and hospitalization for type 2 diabetes (T2D), and to study whether any such association remains in second-generation immigrants. DESIGN: In this follow-up study, the Swedish Hospital Discharge Register was used to identify all hospital
The term gastrointestinal neuromuscular disease describes a clinically heterogeneous group of disorders of children and adults in which symptoms are presumed or proven to arise as a result of neuromuscular, including interstitial cell of Cajal, dysfunction. Such disorders commonly have impaired motor activity, i.e. slowed or obstructed transit with radiological evidence of transient or persistent
In this work the synthesis of waterborne polyurethane/nanosilica nanocomposites by using two differ-ent strategies is presented, starting from a vinyl terminated polyurethane prepolymer (PUP) based onisophorone diisocyanate and polypropylene glycol, and varying the nanosilica content. In one case, thePUP was dispersed in an aqueous solution containing glycerol-functionalized colloidal nanosilica p
Background: Mass screening for celiac disease (CD) as a public health intervention is controversial. Prior to implementation, acceptability to the targeted population should be addressed. We aimed at exploring adolescents' and parents' experiences of having the adolescents' CD detected through mass screening, and their attitudes towards possible future mass screening. Methods: All adolescents (n =
The main purpose of the Thesis work is to conduct an assessment of both the way companies currently account for their waste costs, and of the potential relevancy of engaging in a more comprehensive cost accounting for waste in terms of achieving industrial waste minimisation and cost optimisation. In order to do so, literature about environmental and cost accounting was reviewed, an empirical stud
If as Hersch Lauterpact stated in the most overly quoted Humanitarian Lawyers phrase in Oppenheim's International Law, International Humanitarian Law lies at the vanishing point of International Law, then I would posit that it is only the continuance of education particularly education in LOAC that prevents it from vanishing altogether. The preservation of the buildings housing that education
Liksom en trädstam uppvisar årsringar som kan användas för att beräkna dess ålder, bildas också tillväxtringar i tänderna hos många djur, även hos dem som regelbundet byter tanduppsättning. Detta fenomen noterades av paleontologen Richard Owen redan i mitten av 1800-talet, men det är först de senaste decennierna som forskningen inom tandersättningscykler hos utdöda djur har tagit fart. Så kalladeThe dentine of teeth from five genera of mosasaurs [i.e., Clidastes, Halisaurus, Dollosaurus (Prognathodon),cf. Platecarpus, and Tylosaurus] and a Mesozoic crocodylian (Aigialosuchus) from the Campanian of the Kristianstad Basin, southernmost Sweden, displays two types of incremental growth lines; i.e., von Ebner’s and, for the first time in extinct animals, Andresen’s lines. These lines are homol
Striving to contribute to research on child- and youth spirituality and African theology with a contextually grounded, non-western, qualitative youth perspective, the aim of this study is to seek an understanding of the spirituality of male youth that live on the streets in Nairobi. To fulfil this aim, the research task carried out is an analysis of the source material from six focus group intervi
The so-called capitalist crisis of care has been theorized starting since the 80s. It has been and explored by two literature streams: the ‘feminist’ and the ‘mainstream’. New social and economic challenges in relation to welfare state systems trigger the interest of scholars and policy makers who are looking for sustainable responses to care needs. Welfare states have been repeatedly grouped into
Insects have been recommended by the FAO as a sustainable food alternative to meat. Despite their nutritional quality and sustainability, most Western countries still see insects as belonging far away from the dinner table. Although still a niche market, Denmark has been at the forefront of innovation and adoption of edible insects. I used integral theory to map out the structural, cultural and pe
Here a lung-on-a-chip device was developed and fabricated using 3D-printing of molds. The lung-on-a-chip device was used as a lung injury model by overstretching of murine lung epithelial cells (MLE-12) monolayers, resembling the injury during mechanical ventilation. The cells were exposed to 25% strain, representing pathological conditions seen in ventilator induced lung injury of patients with
Olika motiv kan influera individen till att vilja bli vegetarian, men däremot kan olika individer motiveras av olika motiv (Rosenfeld & Burrow, 2017a:85). Denna studie undersöker och behandlar följande motiv: trend-, sociala-, konsumtionskultur-, etiska- och hälsomotiv. En kvalitativ metod har tillämpats och empirin samlades in genom semistrukturerade intervjuer med vegetarianer i Sverige som
This thesis examines and compares spontaneous metaphor usage in conversations within and between generations. It investigates to what extent they can be seen as motivated by bodily, conventional and situated factors with the help of the Motivation and Sedimentation Model (MSM), which operates with these three levels of meaning. The model combines and integrates earlier accounts of metaphor motivat
Pupils tend to experience ‘attentional fatigue’ after persistently demanding their attentional system during school hours, resulting in decreased psychological well-being and a lack of attention, along with losses of other cognitive functions. Previous research found natural elements in a school environment to restore pupils’ depleted attentional system. The present study aimed at investigating na
Popular summary The environmental and social consequences of predicted climate change are expected to be amplified in urban environments due to their elevated temperatures, which are attributable to a phenomenon known as the Urban Heat Island. As most types of vegetation can provide for cooler air temperatures due to their natural cooling effect, increasing amounts of vegetation in urban areas mig
