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Delamination plays a pivotal role during normal development and cancer. Previous work has demonstrated that delamination and epithelial cell movement within the plane of an epithelium are associated with a change in cellular phenotype. However, how this positional change is linked to differentiation remains unknown. Using the developing mouse pancreas as a model system, we show that β cell delamin
Mouse embryonic stem cell (mESC) lines were derived by crossing heterozygous transgenic (tg) mice expressing green fluorescent protein (GFP) under the control of the rat tyrosine hydroxylase (TH) promoter, with homozygous alpha-synuclein (aSYN) mice expressing human mutant SNCAA53T under the control of the mouse Prion promoter (MoPrP), or wildtype (WT) mice. The expression of GFP and human aSYN wa
European Resuscitation Council (ERC) issued updated guidelines for postresuscitation care in 2015. This paper provides updated Swedish recommendations for neurological prognostication of patients remaining unconscious after cardiac arrest (CA). The prognostication should be based on independent methods; clinical and neurophysiological examinations, imaging and biomarkers. It should not be performe
This paper deals with those provisions of the new EU Regulation No. 2015/848 on Insolvency Proceedings (Recast) that create a system of national insolvency registers and establish a decentralized system for the interconnection of such registers by means of the European e-Justice Portal.
An economic model describing manufacturing costs is implemented within the frame of a case study. The implemented economic model is developed to enable analyses of the cost items and parameters influencing the cost of a part or a batch and also to make simulations for the purpose of investigating the economic outcome of future development activities. The aim of the case study was to identify activ
In this paper we address the problem of generating efficient software implementations for a large class of dataflow programs that is characterized by highly data-dependent behavior and which is therefore in general not amenable to compile-time scheduling. Previous work on implementing dataflow programs has emphasized classes of stream processing algorithms that exhibit sufficiently regular behavio
The paper examines and illustrates different trends in relation to historical energy use-related intensities and corresponding CO2 emission trends. The methodology encompasses a decomposition quantitative approach for estimating decoupling trends to energy use and economic and demographic parameters driving CO2 emission levels. The analysis covers both global and regional trends for the period 197
Sjuktalet och arbetslöheten samvarierar, genom att sjukfrånvaron tenderar att öka då arbetslösheten minskar, och vice versa. I uppsatsen diskuteras denna samvariation samt dess rekation till förtidspensionering, och den dolda arbetslösheten.
The study has shown that BIM is used extensively throughout the entire construction process, with clear benefits and optimizations. The broad usage of BIM shows that all areas have streamlined and become less costly. BIM is well established in the construction process with an exception for the facility management phase. The benefits in the facility management area are well studied but not introduc
Title: System Dynamics Perspective on the Business Model for Sustainability: A Multiple Case Study in the Architecture Industry Purpose: The primary purpose of the study is to explain how the system dynamics between the Value Configuration, Partner Network, and Capabilities work in a Business Model for Sustainability of small and large architecture firms. Methodology: We followed an abductive, q
