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Changes in the levels of arachidonic acid during ischemia in selectively vulnerable areas of the hippocampus were studied in the rat brain. Since neurons in the CA1 region are more vulnerable to ischemia than neurons in the adjacent CA3 region, the release of arachidonic acid in these two regions was measured during decapitation ischemia of 4- to 12-min duration. The concentration of free arachido

This study addresses the question of whether the cyclooxygenase inhibitors indomethacin and diclofenac and the glucocorticosteroid dexamethasone ameliorate neuronal necrosis following cerebral ischemia. In addition, since these drugs inhibit the production of prostaglandins and depress phospholipase A2 activity, respectively, the importance of free fatty acids (FFAs) on the development of ischemic

Växtätare kan påverka ekosystemprocesser, dels genom långsiktiga förändringar av växtsamhällets sammansättning, men också på kortare sikt genom derasmatspjälkning av organiskt material som cyklas genom markens nedbryderorganismer och tillbaka till de primära producenterna. Särskilt störreväxtätare har studerats i stor utsträckning, men i vissa ekosystem som skogar kan de mindre ryggradslösa växtätHerbivory can influence ecosystem processes, partly through long-term changes of the plant community compositions, but also more rapidly through the herbivores’ digestive alteration of the organic matter that is cycled through the soil and back to the primary producers. In the Subarctic mountain birch (Betula pubescens ssp. czerepanovii) forest (SMBF) in Northern Fennoscandia, outbreaks by the geo

PURPOSE: Opioid use disorder has caused significant morbidity and mortality resulting in opioid prescribing limiting laws, such as State Bill 273 in West Virginia. The purpose of this study is to explore the impacts of a restrictive opioid prescription law on physicians in medical practice in West Virginia. METHODS: A qualitative study with open-ended semistructured interviews with a purposive sam

Introduction: The sixth Åland Islands Conference on von Willebrand disease (VWD) on the Åland Islands, Finland, was held from 20 to 22 September 2018. Aim: The meeting brought together experts in the field of VWD from around the world to share the latest advances and knowledge in VWD. Results and discussion: The topics covered both clinical aspects of disease management, and biochemical and labora

Festskriftsbidrag till Antje Jackelén

We aim to answer the question of the effect of a social-purpose-driven ecosystem on value capture from digital health platforms. We call the social-purpose-driven ecosystem a phenomenon which seeks social impact before profits and aims to empower citizens for individual and collective well-being. Thus, capturing value from digital platforms embedded in a social-purpose-driven ecosystem fundamental

This study follows on from a network-based assessment redesign project at a Canadian university, to investigate factors relating to academic engagement and sustained implementation. The project was designed with mini-grants, embedded support and a community of practice. Assessment facilitators worked in discipline clusters to achieve mutual goals for assessment reform targeted at authentic develop

The recent Company of Biologists workshop 'Growth, Division and Differentiation: Understanding Developmental Control', which was held in September 2011 at Wiston House, West Sussex, UK, brought together researchers aiming to understand cell proliferation and differentiation in various metazoans, ranging from flies to mice. Here, we review the common themes that emerged from the meeting, highlighti

Urbana, pluviala översvämningar orsakar stor skada på infrastruktur, byggnader och stadslivet under och efter extremregn. I den här studien har anmälningar och rapporter från försäkringsbolag och VA-huvudmannen i Malmö, VA Syd, analyserats spatialt. Målsättningen var att få en bättre förståelse för de mekanismer som påverkar pluviala översvämningar, dvs. översvämningar från intensiva regn, ibland Urban, pluvial flooding severely effects infrastructure, buildings and urban life during and after extreme rainfall. In this study, spatial analyses of flood claims from insurance companies and the water utility company of Malmö, VA Syd, are used to better understand the mechanisms and characteristics of pluvial flooding. The same data sets are used to analyse how blue-green infrastructure impacts

Introduction Health technology assessment (HTA) is an area that remains less implemented in low- and lower middle-income countries. The aim of the study is to understand the perceptions of stakeholders in Uganda toward HTA and its role in decision making, in order to inform its potential implementation in the country. Methods The study takes a cross-sectional mixed methods approach, utilizing an a

These days, talk of quantum technologies and the coming “quantum revolution” or “quantum leap” is hard to miss. There is a broad agreement that quantum technologies have a high probability of becoming the next disruptive technological development, and the way they should be regulated and the timing of such intervention are issues that are attracting increasing attention. An analysis of how these q

Till bilden av den unge Halldór Laxness (1902–1998) som enfant terrible på Island hörde hans normstridiga stavning och interpunktion, inte oväsentligt i ett land där språknormering gärna blir föremål för symbolstrider. Vid översättning normaliseras dessa språkliga nivåer regelmässigt, även om det finns skäl att anta en generell utveckling under 1900-talet mot ökad adekvans (≈ trohet) […] I förenin