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This thesis is based upon four original papers describing the characterisation of mantle cell lymphoma (MCL) tumours and cell lines in comparison with different populations of normal B cells. Gene expression profiling, which were used in the studies, has during recent years developed as an important tool in characterisation of different types of malignancies. In this thesis, the technique is used
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Ethanol production by the yeast Saccharomyces cerevisiae from dilute acid lignocellulose hydrolyzate was studied with the aim to improve fuel ethanol production. Specifically, the problem of inhibition was addressed. Lignocellulose hydrolyzate contains not only sugars, but also several compounds, such as furfural and 5-hydroxymethyl furfural (HMF), which can inhibit yeast growth and ethanol produc
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Modern military multi-role combat aircrafts need an emergency power system (EPU) to maintain back-up power supply for all normal and degraded flight modes. The reason for this requirement is that modern combat aircrafts are designed with built-in relaxed or negative stability. Inability of the Flight Control System to perform continuous, corrective control surface actuation, due to loss of power
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Two different sensitive microtitre-plate based enzyme immunoassays were developed and evaluated for determination of the model drug compound, budesonide, in blood plasma. In the first approach, high sensitivity was obtained by using amperometric detection in a flow injection system for determination of the enzyme product p-aminophenol. The high sensitivity in the second approach was obtained using
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Ethanol can be produced from lignocellulose by first hydrolysing the material to sugars, and then fermenting the hydrolysate with the yeast Saccharomyces cerevisiae. Hydrolysis using dilute sulphuric acid has advantages over other methods, however, compounds which inhibit fermentation are generated during this kind of hydrolysis. The inhibitory effect of aliphatic acids, furans, and phenolic compo
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This paper examines references of visual product identity in product design. The perception of identity is the result of a composite experience of the presentational and representational dimensions of the product. As consumers to a large degree create their value perceptions of products and brands based on the design of the product, it is important for companies to understand how perceptions of id
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Projects often suffer from lack of logistics considerations in the early phases. Since logistics is not the main focus of the people involved in the project, logistics solutions become reactive rather than proactive. With the increasing global competition, forcing companies to shorten time-to-market for their projects and becoming more cost effective, it becomes increasingly important to manage pr
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Colonialism’ and ‘decolonization’ have been dealt with by postcolonial studies and, more recently, by scholars identified with the ‘de-colonial turn’. At the same time, in the ethnopolitically charged context of contemporary Bolivian society, colonialism and decolonization have become issues of political, existential and even cosmological import. This thesis identifies a need to root the ‘de-colon
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The partitioning of 10% (w/w) lactic acid in ethylene oxide propylene oxide (EOPO) random copolymers and dextran T500 aqueous two-phase systems was studied. An analysis of variance design was applied to investigate the effect of pH, polymer concentration, and addition of polyethyleneimine to the aqueous two-phase systems. The lowest lactate partition coefficient of 0.09 was obtained at pH 6 in the
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Popular Abstract in Swedish Information om smärta, klåda och temperaturförändringar förmedlas till centrala nervsystemet av tunna nervfibrer som leder nervimpulser relativt långsamt. Information om beröring av huden förmedlas istället av grova och snabbt ledande nervfibrer. Det är välkänt att olika känselkvaliteter kan interagera med varandra på olika nivåer i centrala nervsystemet. Vanlig berörinIt is known that stimulation of thin nerve afferents can inhibit itch and pain and that the nociceptive systems have a detailed topographical organisation, with subsystems exhibiting specific excitatory and inhibitory receptive fields. On this basis, a new technique was developed, termed Cutaneous Field Stimulation (CFS), that electrically stimulates thin nerve fibers innervating specific skin fie
