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To support countries in reforming their research and innovation systems, the Directorate-General for Research & Innovation (DG RTD) of the European Commission set up a Policy Support Facility (PSF) under the European Framework Programme for Research & Innovation ‘Horizon 2020’. It aims to support Member States and associated countries in improving their national science, technology and inn
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The prediction of transcription factor binding sites in genomic sequences is in principle very useful to identify upstream regulatory factors. However, when applying this concept to genomes of multicellular organisms such as mammals, one has to deal with a large number of false positive predictions since many transcription factor genes are only expressed in specific tissues or cell types. We devel
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To validate an automatic algorithm for offline T2* measurements, providing robust, vendor-independent T2*, and uncertainty estimates for iron load quantification in the heart and liver using clinically available imaging sequences.
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Lysine-specific chemical crosslinking in combination with mass spectrometry is emerging as a tool for the structural characterization of protein complexes and protein-protein interactions. After tryptic digestion of crosslinked proteins there are thousands of peptides amenable to MSMS, of which only very few are crosslinked peptides of interest. Here we describe how the advantage offered by off-li
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Cognitive robots have started to find their way into manufacturing halls. However, the full potential of these robots can only be exploited through an integration into the automation pyramid so that the system is able to communicate with the manufacturing execution system (MES). Integrating the robot with the MES allows the robot to get access to manufacturing environment and process data so that
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The analysis of a road network could be carried out using different techniques, the most advanced of which for the identification of hazardous sites are based on a statistical tool known as a "Safety Performance Function" (SPF). SPFs are fundamental to procedures in the Highway Safety Manual (HSM) and Safety Analyst, both of which require calibration of the SPFs to local conditions. In the case of
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This year the Swedish Society of Medicineand Lund Society of Medicine have arranged aBerzelius Symposium in Malmo¨/Lund on September24–26, 2008. This is the 1st InternationalSymposium in Sweden on The AgingMale.The purpose is to bring together scientistsand clinicians in this relatively new disciplineto highlight, in a multidisciplinary setting, thecauses and consequences of male aging and itssoci
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Epidemiological studies have linked whole grain intake to the prevention of the metabolic syndrome, obesity and associated chronic diseases such as CVD and T2D. The Nutrition module within the HEALTHGRAIN project, included 10 partners and undertook in vitro, animal and humanin vivo studies with the overall aims of elucidating the components and mechanisms underlying the health benefits of cereal g
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A rapid and simple approach of lactose analysis is proposed based on 3rd generation amperometric biosensors employing cellobiose dehydrogenase (CDH) from Trametes villosa or Phanerochaete sordida immobilised on screen-printed carbon electrodes (SPCEs). After optimisation of the working conditions of the biosensors - pH of the carrier buffer, flow rate and applied potential - the sensors were able
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Popular Abstract in Swedish Ett varmare klimat ökar generellt risken för angrepp av skadeinsekter på jordbruksgrödor, och många skadeinsekter förväntas sprida sig norrut. Den här avhandlingen fokuserar på hur ett varmare klimat kan påverka koloradoskalbaggen, en allvarlig skadegörare i potatisodlingar. Koloradoskalbaggen kom från Mexiko till Europa i början av 1900-talet, och har sedan dess spridiEuropean agriculture is facing the challenge of managing the impact of climate change on food security. Agriculture in a northern temperate climate is likely to benefit from higher temperature and longer growing season while, in the south, crop productivity is likely to decline. Such changes in climate could also affect the population dynamics of insect pests. The Colorado potato beetle (CPB) is o
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A new target chamber as well as a new 7-axes translation stage with goniometer will shortly be implemented at the LIPSION nanoprobe in Leipzig. This new stage should enable linear motion as well as rotary motion with high precision, positioning accuracy and repeatability. These different features have been investigated online as well as offline, with encouraging results. Along with the new equipme
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Background: The Hip disability and Osteoarthritis Outcome Score (HOOS) is a self-administered hip-specific questionnaire intended to evaluate symptoms and functional limitations, and it is commonly used to evaluate interventions in individuals with hip dysfunction or hip osteoarthritis. The HOOS consists of 43 questions in five subscales: Pain, Symptoms, Function in daily living, Function in sport
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Objective To evaluate if obstructive sleep apnoea (OSA) modifies the risk of coronary heart disease, type 2 diabetes (T2D) and diabetic complications in a gender-specific fashion. Design and setting A longitudinal population-based study with up to 25-year follow-up data on 36 963 individuals (>500 000 person years) from three population-based cohorts: the FINRISK study, the Health 2000 Cohort Stud
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The distance of sprinklers below ceiling is of fundamental importance since it has a great influence on activation time. Accepted distances are specified in different sprinkler standards such as NFPA 13, FM 2-0 and EN 12845 for different configurations. This distance is unambiguously defined for flat smooth ceilings, but for corrugated ceilings, such as corrugated metal deck ceilings found in many
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Background: Father's health is important for mothers and unborn/newborn children and knowledge about expectant fathers’ health in relation to lifestyle and psychosocial aspects is essential. Aims: To determine sociodemographic and lifestyle factors, self-reported health and sense of coherence among fathers and partners in relation to their risk for depression and anxiety in early pregnancy. Method
