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Isometric and isotonic relaxation in venous smooth muscle

The time course of relaxation under isometric and isotonic conditions was studied in preparations of rat portal vein which maintained regular phasic contractions in solutions with increased [K-+] and [Ca-2+]. It was found that the smooth muscle during isotonic lengthening was able to carry the afterload for a period of time which was longer than expected from the control isometric response. The di

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Abstract in German Die Verkürzung der Untersuchungszeiten bei der klinischen Magnetresonanztomographie (MRT) bietet für den Patienten den Vorteil einer angenehmeren und schnelleren Untersuchung und erhöht gleichzeitig den Patientendurchsatz. Dies erfordert schnelle und robuste Aufnahmetechniken, welche beispielsweise auch bei der Aufnahme bewegter Organe oder für atemangehaltene Messungen eingeset

CSF studies in violent offenders. II. Blood-brain barrier dysfunction without concurrent inflammation or structure degeneration

Cerebral dysfunction without corresponding structural pathology has been reported in brain imaging studies of violent offenders. Biochemical markers in the CSF reflect various types of CNS pathology, such as blood-brain barrier dysfunction (CSF/S albumin ratio), infectious or inflammatory processes (IgG and IgM indices), neuronal or axonal degeneration (CSF-tau protein) and synaptic de- or regener

Technical feasibility of advanced driver assistance systems (ADAS) for road traffic safety.

This paper explores the technical feasibility of five Advanced Driver Assistance System (ADAS) functions to contribute to road traffic safety, to reach stated European (EU) and national road traffic safety targets. These functions - enhanced navigation, speed assistance, collision avoidance, intersection support and lane keeping - were selected from previous research as adequate substitutes for in

Pain and nutrition as experienced by patients with hip fracture

The purpose of this study was to investigate patients' experiences of care in connection with hip fracture. The care process was examined through non-participant observation, informal field interviews and healthcare records. The findings showed that many factors in the healthcare services directly or indirectly influence patients' perceptions of the quality of care. Some of these factors may depen

Exhaustion is differentiable from depression and anxiety: Evidence provided by the SF-36 vitality scale.

Stress-related exhaustion is an increasingly focused phenomenon, although scientifically not yet fully conceptualised. This is perhaps partly due to the fact that the distinction between exhaustion and other already established concepts, such as depression, is not clear. This study explores whether exhaustion can be differentiated from depression and anxiety, by means of introducing the SF-36 vita

Altered beta-Cell Distribution of pdx-1 and GLUT-2 After a Short-Term Challenge With a High-Fat Diet in C57BL/6J Mice.

Mechanisms involved in the islet adaptation to insulin resistance were examined in mice of the C57BL/6J strain challenged with a high-fat (58%) diet for 8 weeks. Basal hyperglycemia commenced after 1 week, whereas hyperinsulinemia evolved after 8 weeks. Glucose elimination after an intravenous glucose challenge (1 g/kg) was significantly delayed after 1, 4, and 8 weeks on the high-fat diet compare

Phosphagens and intracellular pH in intact rabbit smooth muscle studied by 31P-NMR

Phosphorus-31 nuclear magnetic resonance (NMR) spectra (103.2 MHz) were obtained from rabbit portal vein, urinary bladder, and taenia coli smooth muscle. The muscles were mounted isometrically as strips in a horizontal probe and superfused with oxygenated medium at 23 degrees C. Under these conditions the preparations could remain in a stable metabolic state for at least 24 h. The resonances obser

Ray-tracing analysis of diffractive-refractive X-ray optics

Ray-tracing simulations of mistuned sagittal diffractive - refractive X-ray lenses (DRXL) are presented. In this article, firstly the characteristic aberrations for various types of crystal misalignments within one-crystal and four-crystal DRXLs are considered, and the sensitivity of such an optical system to the mutual misalignment of its components is discussed. The simulations reveal that a DRX

Finns Gud? Feministiska förhållningssätt till en omdebatterad fråga

Artikeln diskuterar några möjliga feministiska förhållningssätt till de religionsfilosofiska positionerna realism och non-realism. Artikeln ifrågasätter därefter positionernas dualistiska förutsättningar avseende existens och sanning och ger ett konstruktivt språkfilosofiskt förslag till hur man kan förstå förhållandet mellan språk och verklighet, där det inte längre blir nödvändigt att åberopa re

Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals

Background: The expression of gene batteries, genomic units of functionally linked genes which are activated by similar sets of cis- and trans-acting regulators, has been proposed as a major determinant of cell specialization in metazoans. We developed a predictive procedure to screen the mouse and human genomes and transcriptomes for cases of gene-battery-like regulation. Results: In a screen tha