Objective: The aim of this study was to assess how participation in party activities with guides affects alcohol consumption among young tourists at an international nightlife resort. Methods: Prospective survey of 112 Danish tourists in Sunny Beach, Bulgaria, who were asked about their drinking and activities with guides on three separate nights out. Results: Participation in party activities wit

BACKGROUND Heavy drinking and drug use is increasingly recognised as a problem in relation to holidays at nightlife resorts. However, studies conducted on the subject to date have relied on retrospective accounts of drinking, and little is known about the course of drinking, consequences and experiences during such holidays. METHODS A prospective study was carried out in Sunny Beach, Bulgaria, of

Nanoindentation is a useful experimental method to characterize the micromechanical properties of materials. In this study molecular dynamics and peridynamics are used to simulate nanoindentation, with a spherical indenter targeting a thin single crystal Cu film, resting on an infinitely stiff substrate. The objective is to compare the results obtained from molecular dynamic simulations to those oNanoindentation is a useful experimental method to characterize the micromechanical properties of materials. In this study molecular dynamics and peridynamics are used to simulate nanoindentation, with a spherical indenter targeting a thin single crystal Cu film, resting on an infinitely stiff substrate. The objective is to compare the results obtained from molecular dynamic simulations to those o

Drawing on data generated through quantitative and qualitative methods, this article explores the prevalence and experiences of substance use, casual sex, commercial sex, and health problems among young Danish tourists at an international nightlife resort in Bulgaria. The article argues that the risks the tourists take should not be interpreted as a symptom of nihilism, pathology, or escapist incl

Purpose: This article aims to determine the prevalence of substance use among young festival-goers and the associations between preferences for different types of music and recent use of different types of licit and illicit drugs. Design/methodology/approach: The article is based on a cross-sectional survey of 1,787 young adults attending a music festival in Denmark. Associations between preferenc

People traveling abroad tend to increase their use of alcohol and other drugs. In the present study we describe organized party activities in connection with young tourists’ drinking, and the differences between young people traveling with and without organized party activities.

Purpose – This article aims to offer an ethnographic account of substances and sex and how they are interrelated in the context of one holiday destination popular among British youth. Current research on British youth abroad and their use of substances is based almost exclusively on survey methods. Similarly, the same research works do not explore, in sufficient detail, sexual relations outside of

Little is known about young adults' use of strip clubs and prostitution during their holidays abroad. This study examined this issue with a sample of 1125 Danish tourists between the ages of 16 and 34, and sought data about the frequency with which they paid for sex and attended strip clubs while they were on holiday. The tourists were surveyed at a Bulgarian airport before their return trip home.

Aim: In western countries, the most prevalent type of illicit substance-use dependence is cannabis dependence. This study aimed at estimating the prevalence of cannabis dependence among music festival visitors. Methods: Based on a survey of 380 music festival guests, we estimated the prevalence of cannabis dependence, as defined by a score of 3 or more on the Severity of Dependence Scale (SDS), as

Background: Music festivals are known to attract a high proportion of drug users. Methods: Using a survey of 1,772 visitors at the Roskilde Festival in Denmark, we assessed substance use at the festival, the incidence of use of substances among never-users and the incidence of use among lifetime users who had not used a substance in the past 12 months. Results: New onset of tobacco use was reporte

Aims To investigate predictors of hangover during a week of heavy drinking in young adults. Design Observational prospective study. Methods A total of 112 young Danish tourists were interviewed on three occasions during their holiday. They completed the Acute Hangover Scale and answered questions about their alcohol consumption and rest duration. The incidence of hangover was analysed as the propo

A new method is developed to synthesize organic microsphere-supported polymer brushes for affinity separation of saccharides and glycoproteins. In the first step, crosslinked polymer microspheres are synthesized using atom transfer radical polymerization (ATRP). The terminal ATRP initiators on the microspheres are used to graft polymer brushes from propargyl acrylate and N-isopropyl acrylamide. Th

Background: Smoldering multiple myeloma (SMM) is an indolent disease stage, considered to represent the transition phase from the premalignant MGUS (Monoclonal Gammopathy of Undetermined Significance) state towards symptomatic multiple myeloma (MM). Even though this diagnosis provides an opportunity for early intervention, few treatment studies have been done and the current standard of care is ob

Several monogenic causes of familial myelodysplastic syndrome (MDS) have recently been identified. We studied two families with cytopenia, predisposition to MDS with chromosome 7 aberrations, immunodeficiency, and progressive cerebellar dysfunction. Genetic studies uncovered heterozygous missense mutations in SAMD9L, a tumor suppressor gene located on chromosome arm 7q. Consistent with a gain-of-f

Context. High resolution stellar spectral atlases are valuable resources to astronomy. They are rare in the 1-5 μm region for historical reasons, but once available, high resolution atlases in this part of the spectrum will aid the study of a wide range of astrophysical phenomena. Aims. The aim of the CRIRES-POP project is to produce a high resolution near-infrared spectral library of stars across

Human enteroviruses (HEV), especially coxsackievirus serotype B (CVB) and echovirus (E), have been associated with diseases of both the exocrine and endocrine pancreas, but so far evidence on HEV infection in human pancreas has been reported only in islets and ductal cells. This study aimed to investigate the capability of echovirus strains to infect human exocrine and endocrine pancreatic cells.

An increasing number of patients are successfully resuscitated from cardiac arrest (CA) and subsequently treated in an intensive care unit due to unconsciousness. Approximately half of these patients will die during the first weeks postarrest, typically after a determination of a poor neurologic prognosis and a decision to withdraw life-sustaining therapy (WLST). These decisions are guided by univ

Scope: Multifunctional diet (MFD), a diet based on multiple functional concepts and ingredients with anti-inflammatory activity, was previously shown to improve different cardiometabolic risk-associated markers in healthy subjects. Here, we assessed the impact of MFD on plasma metabolome and explored associations of the differential metabolites with clinical parameters, searching for metabolic det