Filtyp
The research evaluated retrofitting options for a threestory church community building in Grevie, Sweden, assessing the impacts on energy efficiency, life cycle cost, and environmental concerns. An energy model was generated in IDA ICE to simulate the building performance. Various improvements were tested in two separate retrofit package scenarios. They had the following measures in common: the ad
Knee osteoarthritis (OA) and obesity are closely linked, with obesity being the primary risk factor for OA. This study used the medial meniscus of sows (250 kg, 4–6 years old) as a model for spontaneous OA, comparing them to lighter pigs (110 kg, 7–8 months old). The joints were collected according to the 3Rs principles (Replacement, Reduction and Refinement) and compared using macroscopic and mic
This study investigates the influence of osteoarthritis (OA) disease severity on the bio-composition of the osteochondral junction at the human tibial plateau using Raman microspectroscopy. We specifically aim to analyze the spatial composition of mineralized osteochondral tissues, i.e., calcified cartilage (CC) and subchondral bone plate (SBP) from unfixed, hydrated specimens. We hypothesize that
Dental caries is the most common oral disease that causes demineralization of the enamel and later of the dentin. Depth-wise assessment of the demineralization process could be used to help in treatment planning. In this study, we aimed to provide baseline information for the development of a Raman probe by characterizing the mineral composition of the dental tissues from large composition maps (6
The influence of joint degeneration on the biomechanical properties of calcified cartilage and subchondral bone plate at the osteochondral junction is relatively unknown. Common experimental difficulties include accessibility to and visualization of the osteochondral junction, application of mechanical testing at the appropriate length scale, and availability of tissue that provides a consistent r
Bridge monitoring is essential for ensuring their long-term safety, reducing disruptions, and supporting economic and social activities. Traditional monitoring techniques rely on periodic inspections and contact-based sensing systems, which, while effective, have limitations due especially to high installation and maintenance costs. Satellite-based Synthetic Aperture Radar Interferometry (InSAR) o
The Swedish province of Västergötland is home to around 180 churches from the Middle Ages and played an important role in the processes of Christianisation and subsequent state-building of Sweden. The roof structures of these churches act as a window to our past where we can learn information on construction dates and techniques as well as the use of local resources, such as timber. In this joint
This study presents the fabrication of all-dielectric silicon-based twisted L-shape metamaterials using a two-step electron-beam glancing angle deposition approach. Systematic chiroptical characterization and optimization are performed through Mueller matrix generalized spectroscopic ellipsometry and finite element modeling, demonstrating tunable, broadband chirality response with potential applic
We report the fabrication of three-dimensional topological insulator heterostructures using a single-step bottom-up approach based on directional solidification. These materials exhibit atomically smooth interfaces, preserving topological surface states and enabling hetero-junction formation. This scalable approach paves the way for advancements in spintronics, quantum computing, and novel optoele
Meta-analyses are vital for synthesizing evidence in medical research, but conflicts of interest can introduce research bias, undermining the reliability of the synthesized findings. This paper proposes a new robust Bayesian meta-analysis model. The model inflates uncertainty of low-quality studies and incorporates a bias term for studies subject to conflicts of interest. Using a random-effects mo
Enzymes serve as biological catalysts in a wide range of applications, from household products to industrial processes, research, diagnostics and forensic science. They accelerate reactions with high specificity under mild reaction conditions and are essential for life. Advances in recombinant DNA technology have enabled the use of microorganisms as efficient cell factories for production of heter
Understanding 3D human interactions is fundamental for fine-grained scene analysis and behavioural modeling. However, most of the existing models predict incorrect, lifeless 3D estimates, that miss the subtle human contact aspects–the essence of the event–and are of little use for detailed behavioral understanding. This paper addresses such issues with several contributions: (1) we introduce model
Aims: Spontaneous coronary artery dissection (SCAD), causing acute coronary syndrome (ACS), primarily in middle-aged women, is diagnosed with invasive coronary angiography (ICA). Due to the risk of dissection propagation with ICA, a non-invasive diagnostic tool is needed. We investigated coronary computed tomography angiography (CCTA) findings in acute SCAD, as well as the inter-modality agreement
Power required to fly for a bird generally follows a U-shaped function of airspeed, with higher cost at both low and high speeds. Because power required increases with body mass faster than power available from flight muscles, larger birds may experience restricted flight speed ranges and climbing capabilities. Previous studies found limited flight performance in cormorants. Adapted for both fligh
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafau
Al-Hoorie, Hiver, and In'nami (2024) offer compelling arguments for why L2 motivational self-system research is currently in a state of validation crisis. Seeking a constructive resolution to the crisis, in this response we argue that two fundamental conditions are needed for the field to emerge stronger: psychological readiness and methodological maturity. For psychological readiness, we call for
We present memory-based language modeling as an efficient, eco-friendly alternative to deep neural network-based language modeling. It offers log-linearly scalable next-token prediction performance and strong memorization capabilities. Implementing fast approximations of k-nearest neighbor classification, memory-based language modeling leaves a relatively small ecological footprint both in trainin
Introduction: Myocarditis is a complex cardiac disorder with multifactorial etiology, characterized by myocardial inflammation, cardiomyocyte damage, and fibrosis. Left untreated, myocarditis may lead to acute and chronic heart failure and life-threatening arrhythmias. Reliable experimental models of myocarditis are required to study the underlying pathological mechanisms of the disease and to dev
Contamination or damage to X-ray optics is becoming increasingly problematic for beamlines at 3rd and 4th generation storage-rings and FEL sources. Carbon contamination, induced by ultra-intense photon-beams, can cause a major loss in flux, focusing power, and specific absorptions which are detrimental to spectroscopy. For new light sources, with higher coherence, intensity, and repetition rates,
