Filtyp
Aqueous redox flow batteries (RFBs) as grid-scale energy storage devices hold great potential to accomodate the rising demand for intermittent renewable energy sources. A significant parameter that enhances the sustainability of RFBs is selecting the appropriate redox species. In this study, we investigated the application of lignosulfonate as a redox species for the negolyte of aqueous RFBs becau
BACKGROUND: Heart failure (HF) is characterized by hemodynamic derangements that are likely to mediate systemic metabolic perturbations but limited data are available. Plasma metabolite profiling provides opportunities for comprehensive investigation of such perturbations. Here, we aimed to characterize plasma profiles that associate with HF and their relationship with central hemodynamics, sympto
Within the stroma of pancreatic ductal adenocarcinoma (PDAC), mesenchymal cells differentiate into cancer-associated fibroblast (CAF) subtypes that differentially mediate disease progression. Defining the regulatory mechanism and diversity of CAF subtypes could identify potential therapeutic strategies to harness the tumor-suppressive activities of CAFs. To address this, we utilized single-cell RN
Biomass gasification gas (BGG), a carbon-neutral renewable fuel and important hydrogen carrier, holds significant promise for sustainable energy systems. However, its practical implementation is challenged by combustion instability and elevated NOx emissions, primarily due to localized high-temperature zones induced by the hydrogen content. MILD (Moderate or Intense Low-oxygen Dilution) combustion
Alison Scott–Baumann’s Paul Ricoeur: Empowering Education, Politics and Society employs Ricoeur’s philosophy to unpack contemporary universities’ struggles with polarisation and activism. Though short in form, this rich critical study illuminates how universities understand themselves and why fostering dialogue around disagreements and controversies can enable more inclusive, empowered academic co
This chapter examines recent picture books by Muslim women authors as creative interventions in a literary field shaped by secularist norms, racialised market conventions, and the marginalisation of devotional themes. It begins by identifying the conceptual problems that structure scholarship on “religious children’s literature,” particularly the reliance on a rigid religious/secular binary. Such
Measurements of inclusive and differential production cross-sections of a top-quark-top-antiquark pair in association with a W boson (tt¯W) are presented. They are performed by targeting final states with two same-sign or three isolated leptons (electrons or muons) and are based on s = 13 TeV proton-proton collision data with an integrated luminosity of 140 fb−1, recorded from 2015 to 2018 with th
Objective: To determine whether combining routine cross-cultural cognitive assessments with plasma phosphorylated tau217 (p-tau217) increases diagnostic accuracy in identifying Alzheimer's disease (AD) in a consecutive mixed memory clinic cohort of ethnically diverse patients. Methods: We included 201 memory clinic patients originating from 42 different countries. Patients were examined with the M
Aggregation of the hyperphosphorylated tau protein is a central driver of Alzheimer’s disease, and its accumulation exhibits a rich spatiotemporal pattern that unfolds during the course of the disease, sequentially progressing through the brain across axonal connections. It is unclear how this spatiotemporal process is orchestrated, namely, to what extent the spread of pathologic tau is governed b
REM sleep behavior disorder (RBD), is a prodromal synucleinopathy affecting a subset of Parkinson’s disease (PD) patients and associated with neuropsychiatric symptoms. This study compared the genetic profiles of 13,020 PD patients with probable RBD (PD + RBD) and 5403 without (PD-RBD) using genome-wide association study (GWAS). RBD was assessed by questionnaires or self-reporting. Potential genet
Background: Socioeconomic status (SES) can influence health outcomes. Both SES and older age are associated with polypharmacy, health literacy, and quality of care. Understanding how SES influences healthcare experiences of older adults with polypharmacy can serve to inform future interventions aiming at optimising patient care. Therefore, we investigated the association between older patients’ SE
Aims: There is current apprehension among some clinicians and conflicting evidence regarding ocular complications in relation to Glucagon-like peptide-1 receptor agonists (GLP-1RAs). We aimed to generate multi-disciplinary, expert-led consensus recommendations relating to ocular complications to facilitate optimum prescribing of GLP-1RAs. Materials and Methods: A modified Delphi was conducted foll
Variation in the structure and size of the eye in relation to light environments is well-documented across animal taxa. However, the long-term effects of ultraviolet radiation (UVR) on eye size across generations remain understudied, despite natural fluctuations in UVR being common in aquatic habitats. Here, we used Daphnia magna to test whether an evolutionary history of UVR threat modifies plast
Key message: A candidate gene exhibiting pleiotropic effect on twelve different seed size and weight traits was identified through a combination of evidence from population genetic selection, GWAS, earlier QTL studies, transcriptome analysis, and transgenic analyses. Abstract: Peanut is an important oilseed crop. Seed weight and size significantly impact yield, leading to the identification of num
Scale loss is a quintessential hydrodynamic adaptation in marine reptiles, and paralleled the pelagic specializations of Mesozoic ichthyosaurs, plesiosaurs, and metriorhynchid crocodylians, as well as the modern Leatherback Sea turtle (Dermochelyidae). By contrast, modern hard-shelled sea turtles (Cheloniidae) retain both scutes and scaly flippers, despite evolving from among partially scale-less
To prepare students for addressing wicked problems such as climate change and inequality, higher education must foster systemic and interdisciplinary thinking. We developed a flexible, interactive workshop grounded in sustainability goals and transitions theory to promote abductive reasoning across disciplines. Using cases on food waste, fashion, and e-waste, the workshop was tested in four divers
