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BACKGROUND: There is currently little evidence regarding the selection of patients for clinical trials in Parkinson's Disease (PD), especially those involving experimental therapies delivered using invasive techniques.OBJECTIVE: Understanding which patients are recruited will increase awareness of issues regarding parity of access to clinical trials and have an impact on the wider applicability of
The periodic formation of plant organs such as leaves and flowers gives rise to intricate patterns that have fascinated biologists and mathematicians alike for hundreds of years [1]. The plant hormone auxin plays a central role in establishing these patterns by promoting organ formation at sites where it accumulates due to its polar, cell-to-cell transport [2-6]. Although experimental evidence as
OBJECTIVE(S):: We explored incidence, predictors, and long-term prognosis of hospital admissions attributed to reflex syncope and orthostatic hypotension. METHODS:: We analyzed a cohort of 32?628 individuals (68.2% men; age, 45.6?±?7.4 years) without prevalent cardiovascular disease over a follow-up period of 26.6?±?7.5 years. RESULTS:: One thousand and fourteen persons (3.1%, 1.2 per 1000 person-
Purpose: To study the effectiveness of Exergames in communal psychiatry for persons with severe mental illness, a randomized cluster study was performed. The hypothesis was to increase physical activity habits to improve somatic health. To identify factors promoting or impeding the use of the Exergames. Methods: Assessments of BMI, blood pressure, physical fitness, SF36, GAF and social interaction
Although reports of pharmaceutical bioconcentration in aquatic organisms are increasing, less is known about trophic transfer in aquatic food webs. The bioaccumulation and trophodynamics of sertraline and fluoxetine, 2 selective serotonin reuptake inhibitors (SSRIs) frequently detected in aquatic environments, were tested by exposing constructed aquatic food chains to SSRIs under controlled labora
Transplantation of embryonic porcine neurons may restore neurological function in patients with Parkinson's disease, if immunological rejection could be prevented. This study was performed to investigate the role of natural killer cells (NK cells) and NK1.1+ T cells (NK T cells) in the rejection of neural xenografts. A cell suspension was prepared from the ventral mesencephalon of 26-27-day-old pi
Due to increasing demand for software project managers in industry, efforts are needed to develop the management-related knowledge and skills of the current and future software workforce. In particular, university education needs to provide to their computer science students not only technology-related skills but, in addition, a basic understanding of typical phenomena occurring in industrial (and
Hardwood spent sulphite liquors (HSSLs) are by-products from the pulping industry rich in pentoses, which are not yet fully exploited for bioprocessing, namely for the production of bioethanol. The sustainable fermentation of pentoses into bioethanol is a challenge to overcome. Besides sugars, HSSLs contains inhibitors that decrease the possibility of bioprocessing of these by-products. Neverthele
The Lorentzian lifetime widths of the 4d and 4f levels in the sixth-period elements W74 to Bi83 have been measured using photoelectron spectroscopy. A compilation of 4f-level widths from the literature is also made. The general trend of the 4f-level widths is well reproduced by McGuires calculations, although the absolute widths seem to be underestimated. The 4d5/2-level width shows a remarkable c
Nitric oxide (NO) acts as a modulator of neuronal transmission in mature neuronal systems, including the retina. Recently, NO has also been suggested to have a trophic function during development. We examined immunocytochemically the distribution of NO-producing cells in developing and transplanted rabbit retinas. An antibody detecting the neuronal isoform of its biosynthetic enzyme, nitric oxide
Patients with rheumatoid arthritis (RA) and other inflammatory joint disorders (IJD) have increased cardiovascular disease (CVD) risk compared with the general population. In 2009, the European League Against Rheumatism (EULAR) taskforce recommended screening, identification of CVD risk factors and CVD risk management largely based on expert opinion. In view of substantial new evidence, an update
The purpose of the study is to investigate how the secrecy that prevails between municipalities, more precisely between social administrations, can be an obstacle in the case of a family home placement. Four theories have been used in this study to analyze the results: Michael Lipsky's grassroots bureaucracy, Attachment theory by Bowlby, trauma-informed care by Boswell and Batch, and emotions
Den här rapporten undersöker samt jämför det möjliga användandet av olika tillverkningsmetoder i produktionen av varianthålade plattor vid Alfa Lavals produktion i Lund. De tre metoderna är stansning med excenterpressar, abrasiv vattenskärning och laserskärning, där de två förstnämnda används i Alfa Lavals produktion i dagsläget. Syftet med projektet är att förkorta ledtider, genom att hitta en meThis report investigates and compares the possible use of different manufacturing methods in production of odd-holed plates at Alfa Laval’s site in Lund. The three methods are punching with eccentric presses, abrasive water jet cutting and laser cutting, with the first two being used currently at Alfa Laval. The aim of the project is to shorten the lead times, by finding a method that is efficient
Flood risk is influenced not only by climate change but also underlying factors including unplanned urbanization, environmental degradation, poverty, social inequalities and weak governance. Given its complexity, effective flood risk management requires a better understanding of its conceptual context and comprehensive assessments that beyond hazard consider exposure, vulnerability and capacity. T
With an annual production of 1.4 million tonnes of fish, Morocco is currently the largest seafood producer in African and Arab countries. However, a vast majority of fish labelled as Moroccan come from the maritime zone of Western Sahara, the last non-self-governing territory in Africa that has been occupied by Morocco since 1975. Furthermore, the fish stock off the Western Saharan coast is at the
The rising levels of carbon dioxide in the atmosphere is one of the most pressing matters right now. Before the industrial revolution, the atmosphere had a concentration of 0,02% which has increased to 0,04% due to human progress. This increase results in melting glaciers, ruined farmland, and more unpleasant consequences. Counter measures of today involve moving away from fossil fuels and relyin
The emergence of artificial intelligence, especially machine-learning methods, challenges the set of legal guarantees put in place in Europe to combat discrimination and ensure equal treatment. This paper will focus on cases of algorithmic discrimination in the context of recruitment as a business practice. Particular in the field of recruitment of workers, which has always been a field where EU n
The present thesis examines how the museum visitor’s experience is being transformed by various developments and particularly by the advent of virtual reality technology. The research focused on identifying the problems of communicating the archaeological information to the museum audiences while highlighting best practices and proposing solutions. The immersive function of virtual reality was exa
Central to the field of agrarian political economy, is rural development and capitalism’s advancement in the countryside and its consequences for the peasantry, ‘the agrarian question’. With the present case study, I examine the interplay between social relations of production and agrarian change in eastern Bolivia. Using the case study of Ramada, a small indigenous community, this dissertation in
