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What is ideal genetic counselling? A survey of current international guidelines

The objective of this article is to review guidelines that address counselling in the context of genetic testing in order to summarise what aspects of counselling they consider most important, and to examine how they construct the ideal of genetic counselling. Guidelines were collected by examining the websites of different international professional, political, ethical and patient organisations,

Quality of life and toxicity in breast cancer patients using adjuvant TAC (docetaxel, doxorubicin, cyclophosphamide), in comparison with FAC (doxorubicin, cyclophosphamide, 5-fluorouracil).

Abstract in UndeterminedThe aim of this study was to compare two regimens of chemotherapy in patients with breast cancer, including FAC (doxorubicin, cyclophosphamide, and 5-fluorouracil) and TAC (docetaxel, doxorubicin and cyclophosphamide); and analyze the toxicity of these treatments and observe patient's health-related quality of life.Health-related quality of life was assessed for up to 4 mon

Increasing iron concentrations in surface waters - a factor behind brownification?

Browning of inland waters has been noted over large parts of the Northern hemisphere and is a phenomenon with both ecological and societal consequences. The increase in water color is generally ascribed to increasing concentrations of dissolved organic matter of terrestrial origin. However, oftentimes the increase in water color is larger than that of organic matter, implying that changes in the c

Visualizing the World. Epistemic Strategies in the History of Scientific Illustrations

The history of scientific illustrations is a story that correspond the cultural, economic, political and scientific history of the world. A look into the history of sciences displays that pictures and illustrations had a decisive role for the sciences progressive success and rising societal status from the sixteenth century. The illustrations visualized the unknown to graspable facts. Without the

Intrinsic femtosecond charge generation dynamics in single crystal CH3NH3PbI3

Hybrid metal-organic perovskite solar cells have astounded the solar cell community with their rapid rise in efficiency while maintaining low-cost fabrication. The intrinsic material photophysics related to the generation of free charges, their dynamics and efficiency, however, remains to be understood. As fabrication techniques improve, larger crystal grain sizes have been shown to be a critical

Heterogeneous nuclear ribonucleoprotein C proteins interact with the human papillomavirus type 16 (HPV16) early 3'-untranslated region and alleviate suppression of HPV16 late L1 mRNA splicing.

In order to identify cellular factors that regulate human papillomavirus type 16 (HPV16) gene expression, cervical cancer cells permissive for HPV16 late gene expression were identified and characterized. These cells either contained a novel spliced variant of the L1 mRNAs that bypassed the suppressed HPV16 late, 5'-splice site SD3632, produced elevated levels of RNA-binding proteins SRSF1 (ASF/SF

Boundary singularities of plurisubharmonic functions

I denna avhandling studeras en särskild kategori av subharmoniska funktioner, det vill säga reellvärda funktioner vars värde i en specifik punkt är mindre än eller lika med funktionens medelvärde på sfärer med centrum i punkten. Sådana funktioner återfinns på flera håll i vetenskapen. Ett exempel är temperaturen i ett bord efter att en värmeslinga slagits på längs bordets rand. I detta fall kommerWe study the Perron–Bremermann envelope P(μ, φ):=sup{u(z) ; u ∈ PSH(Ω), (ddcu)n≥ μ, u^* ≤ φ} on a B-regular domain Ω. Such envelopes occupy a central position within pluripotential theory as they, for suitable μ and φ harmonic and continuous on the closure of Ω, constitute unique solutions to the Dirichlet problem for the complex Monge–Ampère operator. Much is also known about the measures that gu

Impact of storage time prior to cryopreservation on mechanical properties of aortic homografts

Optimal time spans in homograft procurement are still debatable among tissue banks and needs to be further investigated. Cell viability decreases at longer preparation intervals, but the effect on collagen and elastic fibers has not been investigated to the same extent. These fibers are of importance to the homograft elasticity and strength. The objective of this study was to analyze the mechanica

Programme syllabus cmes

Utbildningsplan_SAMES_eng.pdf SAMES, Master of Science (120 credits) in Middle Eastern Studies, 120 credits Masterprogram i Mellanösternstudier, 120 högskolepoäng Second cycle degree programme requiring previous university study _____________________________________________________________ Details of approval The syllabus was approved by the Board of the Faculty of Social Sciences 23 November 2017

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/programme_syllabus_cmes.pdf - 2026-05-23

Minutes GS Board 240603

Graduate School Graduate School Board, 2024-06-03 In attendance Board members Lena Karlsson Director of Studies, Graduate School Leysan Storie Program Director, Middle Eastern Studies Catia Gregoratti Program Director, Global Studies Marta Kolankiewicz Program Director, Social Studies of Gender Christopher Swader Program Director, Social Scientific Data Analysis Axel Fredholm Sociology Ida Nafstad

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2024-09/Minutes%20GS%20Board%20240603.pdf - 2026-05-23

Nearshore Currents in Southeastern Scania

The South East Coast of Scania is a popular destination for both Swedish and foreign tourists. The long and wide sandy beaches are well visited by swimmers and beachgoers, but the waters have shown to be treacherous at times. In Au- gust 2015, two German tourists drowned after getting caught in a probable rip current in the proximity of Hav ̈ang beach. Six months after the accident, this thesis st

The Design and Linearization of 60GHz Injection Locked Power Amplifier

The RF power amplifier is one of the most critical blocks of transceivers, as it is expected to provide a suitable output power with high gain, efficiency and linearity. In this paper, a 60-GHz power amplifier based on an injection locked structure is demonstrated in a standard 65 CMOS technology. The PA core consists of a cross-coupled pair of NMOS transistors with an NMOS current source. This st

Att inte bli kriminell: en kvalitativ studie om unga studenters reflektioner kring faktorer i en uppväxt som är väsentliga för ett icke kriminellt handlande

Background:The research of social science tends in many cases lean towards an approach that focus on negatively influencing factors, rather than health promoting factors from a salutogenic perspective. In the field of criminology, this approach commonly investigates reasons behind criminal behavior instead of studying the salutogenic factors, i.e. reasons why people do not engage in a criminal lif

32 06032016 679 32 LeonNovelo Bol Soc Mat Mex 2013

Bol. Soc. Mat. Mexicana (3) Vol. 19, 2013 TWO APPLICATIONS OF PERMUTATION TESTS IN BIOSTASTICS LUIS LEÓN-NOVELO, KAISA M. KEMPPAINEN, ALEXANDRIA ARDISONNE, AUSTIN DAVIS-RICHARDSON, JENNIE FAGEN, KELSEY GANO, ERIC W. TRIPLETT, AND TEDDY STUDY GROUP ABSTRACT. We show two examples of how we answer biological questions by converting them into statistical hypothesis testing problems. We consider gene a

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/32%2006032016_679_32_LeonNovelo_Bol%20Soc%20Mat%20Mex_2013.pdf - 2026-05-23

83 10262018 679 83 MP194 Lee MASA 2017

Model Assisted Statistics and Applications 12 (2017) 227–237 227 DOI 10.3233/MAS-170397 IOS Press A new framework for prediction and variable selection for uncommon events in a large prospective cohort study Hye-Seung Lee∗ and Jeffrey P. Krischer Health Informatics Institute, University of South Florida, Tampa, FL, USA Abstract. When prediction is a goal, validation utilizing data outside of the p

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/83%2010262018_679_83_MP194_Lee_MASA_2017.pdf - 2026-05-23

Filter Plate–Based Screening of MIP SPE Materials for Capture of the Biomarker Pro-Gastrin-Releasing Peptide

Affinity-based solid-phase extraction (SPE) is an attractive low-cost sample preparation strategy for biomarker analysis. Molecularly imprinted polymers (MIPs) as affinity sorbents offer unique opportunities for affinity SPE, due to their low manufacturing cost and high robustness. A limitation is the prediction of their affinity; therefore, screening of analyte recovery and specificity within a l

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

Epidemiological studies consistently show that circulating sex hormone binding globulin (SHBG) levels are lower in type 2 diabetes patients than non-diabetic individuals, but the causal nature of this association is controversial. Genetic studies can help dissect causal directions of epidemiological associations because genotypes are much less likely to be confounded, biased or influenced by disea

Evaluation of ecosystem dynamics, plant geography and terrestrial carbon cycling in the LPJ dynamic global vegetation model

The Lund-Potsdam-Jena Dynamic Global Vegetation Model (LPJ) combines process-based, large-scale representations of terrestrial vegetation dynamics and land-atmosphere carbon and water exchanges in a modular framework. Features include feedback through canopy conductance between photosynthesis and transpiration and interactive coupling between these 'fast' processes and other ecosystem processes in