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Dose dependence of mass and microcalcification detection in digital mammography: free response human observer studies.

The purpose of this study was to evaluate the effect of dose reduction in digital mammography on the detection of two lesion types-malignant masses and clusters of microcalcifications. Two free-response observer studies were performed-one for each lesion type. Ninety screening images were retrospectively selected; each image was originally acquired under automatic exposure conditions, correspondin

Benchmarking of Processes for Managing Product Platforms - a Case Study

A case study is presented in which two organisations have participated in a benchmarking initiative to discover improvement suggestions for their processes for managing product platforms. The initiative, based on an instrument which consists of a list of questions, has been developed as part of this study and contains eight major categories of questions that guide the participating organisations t

Development of a simple hollow fibre supported liquid membrane extraction method to extract and preconcentrate dinitrophenols in environmental samples at ng L-1 level by liquid chromatography

An easy and rapid hollow-fibre supported liquid membrane method (HFSLM) has been developed to extract and determinate the total concentration of four dinitrophenols in environmental water at ng L-1 level. This extraction method provides a high selectivity, short extraction time and very low cost for real samples. It is a three-phase system, aqueous-organic-aqueous, where the organic solvent is hel

Dynamics of water molecules in the active-site cavity of human cytochromes P450

We have studied the dynamics of water molecules in six crystal structures of four human cytochromes P450, 2A6, 2C8, 2C9, and 3A4, with molecular dynamics simulations. In the crystal structures, only a few water molecules are seen and the reported sizes of the active-site cavity vary a lot. In the simulations, the cavities are completely filled with water molecules, although with similar to 20% low

MicroRNAs in islet hormone secretion

Pancreatic islet hormone secretion is central in the maintenance of blood glucose homeostasis. During development of hyperglycaemia, the β-cell is under pressure to release more insulin to compensate for increased insulin resistance. Failure of the β-cells to secrete enough insulin results in type 2 diabetes (T2D). MicroRNAs (miRNAs) are short non-coding RNA molecules suitable for rapid regulation

The metamorphic and magmatic record of collisional orogens

The Cenozoic Himalaya-Tibet orogen is generally regarded as the archetypal continental collision zone and is often used as an analogue for interpreting ancient orogenic events. However, given the wide diversity observed in present-day collisional mountain belts, the extent to which such inferences can be made remains debated. In this Review, we compare the metamorphic and magmatic record of the Hi

High in Utero Exposure to Perfluoroalkyl Substances from Drinking Water and Birth Weight: A Cohort Study among Infants in Ronneby, Sweden

In 2013, the drinking water for one-third of the households in Ronneby, Sweden, was found to be contaminated by perfluorinated alkyl substances (PFAS, >10,000 ng/L) from Aqueous Film Forming Foam (AFFF). In utero PFAS exposure can influence birth weight, but little is known about the effects at very high levels. This study aimed to examine the association between in utero PFAS exposure and birth w

cDC1 deficient mice are protected from reinfection with rotavirus despite a reduced neonatal plasma cell response

Rotavirus and the Neonate: Memories of infections gone by Despite advances made through vaccination, the disease burden of rotavirus in the developing world remains high, largely affecting children below the age of 5 and remaining the leading cause of death from viral gastroenteritis (Fig. 1). Socio-economic factors, as well as poor response to vaccination in the developing world are believed to

Personals definition av delaktighet och dess komplexitet i praktiken – En kvalitativ studie om personals upplevelser avseende HVB-hemsplacerade ungdomars delaktighet

The aim of this study was to inquire how staff that works with youth that are placed in out of home care reason around the definition of participation. We also examined how they felt about their possibility to influence youth participation during their placement regarding the daily routines. We also looked into how the staff felt regarding their possibility to influence their work with the youth’s

Microloans from an organizational perspective - A case study from Cambodia

The purpose of this study was to understand how identity could be created in organizations working with microloans. The purpose was also to see how this identity was manifested in term of rules, guidelines and symbolic manifestations. The result of this thesis was analyzed from a symbolic perspective which worked as a tool to understand how identity could be created in an organization working with

Bridges and Barriers: Physiotherapy and the Physiotherapist's experience of treating Musculoskeletal Disorders in Western Ecuador. A qualitative study.

BACKGROUND: Ecuador is a Spanish speaking country located in northwestern South America with an approximate population of 16 million people. It is considered a developing country. The public healthcare system is divided into three branches and there are also private services available. Musculoskeletal disorders are overly represented in the developing world, especially where poverty and rural livi

Tillämpningen av korrigeringsregeln och dess följdverkningar

Enligt den så kallade korrigeringsregeln i 14 kap. 19 § IL följer att när ett re-sultat av en näringsverksamhet blir lägre, till följd av att villkor som avtalats avviker från vad som skulle ha avtalats mellan sinsemellan oberoende nä-ringsidkare, ska resultatet beräknas till det belopp som det skulle uppgått till om sådana villkor inte funnits. Bestämmelsen är ett uttryck för en internation-ellt Chapter 14 § 19 of the Swedish income taxation act, also known as the “cor-rection rule”, states that when the result of a business is lower than it should be because a contractual term deviates from what would be the contractual terms between independent businesses, the result shall be calculated as if such contractual terms did not exist. The rule is a manifestation of the international-ly recog

Tredjepartsansvar vid användandet av M&A-försäkringar i samband med privata företagsförvärv

Företagsförvärv är en stor del av vårt näringsliv och har varit det sedan sent 1800-tal efter industrialiseringen. Ett företag byter ägare, en sammanslagning sker eller en verksamhet läggs ner. Resultaten kan vara många och det påverkar samhället i stort likväl som individer. Företagsförvärv delas upp i olika kategorier, vilket möjliggör stor variation, varje förvärv är unikt. I denna uppsats beröM&A is a large part of our business sector and has been since the late 1800s after the industrialization. A company changes owners, a merger takes place or a business is closed. The results can be many and it affects society as a whole as well as individuals. M&A is divided into different categories, which allows for great variation and each acquisition being unique. This thesis focuses on

Bygglov och markrättigheter

Om någon vill ändra användningen av en byggnad, bygga till eller bygga nytt krävs oftast bygglov. Beslut om bygglov fattas av byggnadsnämnden. Om den sökta åtgärden vidtas utanför detaljplan skall alltid sakägare höras och ges tillfälle att yttra sig. Om den sökta åtgärden verkställs inom detaljplanerat område behöver detta endast ske om åtgärden innebär en avvikelse från detaljplanen. ExamensarbTo change the features of a existing building or to build a new building a building permit is needed. The building department at the municipality decides about building permits. The building departments inspection of the applied building permit are a public law inspection and are limited by the Planning and Building Act. Civil rights as ownership and easements are not to be included in the buildin

Bygglov och markrättigheter

Om någon vill ändra användningen av en byggnad, bygga till eller bygga nytt krävs oftast bygglov. Beslut om bygglov fattas av byggnadsnämnden. Om den sökta åtgärden vidtas utanför detaljplan skall alltid sakägare höras och ges tillfälle att yttra sig. Om den sökta åtgärden verkställs inom detaljplanerat område behöver detta endast ske om åtgärden innebär en avvikelse från detaljplanen. ExamensarbTo change the features of a existing building or to build a new building a building permit is needed. The building department at the municipality decides about building permits. The building departments inspection of the applied building permit are a public law inspection and are limited by the Planning and Building Act. Civil rights as ownership and easements are not to be included in the buildin

Det möjligas politik: Om möjligheternas kristallisering och politikens omöjliga löfte

A well-known maxim defines politics as "the art of the possible". This definition implies that the nature of politics is relative to specific circumstances and derives from an adoption of the line of action possible under given circumstances; correlated to this is a rejection of political activities whose realisation is impossible while being subjected to these circumstances. This essay

"Hoy por ti, mañana por mi"

Cooperative and reciprocal practices within agriculture have been widely discussed as important strategies in order to reduce risks and costs of labour and capital acquisition. Within the Andes reciprocal norms appear to be particularly institutionalized due to their historical rootedness in Andean culture. With the present case study I sought to examine reciprocal exchange practices in agricultur

Soil drying-rewetting and its influence on ecosystem carbon fluxess

Torr jord ger ifrån sig mer koldioxid när det regnar När det regnar på torr jord bildas under en kort tid mycket mer koldioxid än vad jorden vanligtvis avger. Detta fenomen har varit känt sen 1950-talet och kallas enkelt för torkning och återfuktning. Även om vi vet att det sker så vet vi väldigt lite om varför det sker. Till en början trodde man att det hade att göra med en ökad aktivitet hos ma