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With the shift of focus of the regulatory bodies, from fixed process conditions towards flexible ones based on process understanding, model-based optimization is becoming an important tool for process development within the biopharmaceutical industry. In this paper, a multi-objective optimization study of separation of three insulin variants by reversed-phase chromatography (RPC) is presented. The

We discuss thermal fluid-structure interaction processes, where a simulation of the time-dependent temperature field is of interest. Thereby, we consider partitioned coupling schemes with a Dirichlet-Neumann method. We present an analysis of the method on a model problem of discretized coupled linear heat equations. This shows that for large quotients in the heat conductivities, the convergence ra

Cephalopods have very conspicuous eyes that are often compared to fish eyes. However, in contrast to many fish, the eyes of cephalopods possess mobile pupils. To increase the knowledge of pupillary and thus visual function in cephalopods, the dynamics of the pupil of one of the model species among cephalopods, the common octopus (Octopus vulgaris), was determined in this study. We measured pupilla

Most nuclear reactors, both in Sweden and worldwide, are enclosed by a prestressed concrete containment. The main purpose of the containment is to prevent any radioactive discharge to the environment in the event of a major internal accident. The performance and structural integrity of the containment depends on the compressive stresses induced in the concrete by the prestressing system. However,

Public policy conflicts emerge when feelings of scarcity and different interests dominate interactive process among the government and the public. The stakeholders struggle in a lower violence capacity but broad range of conflicting issues. Thus, some parties may use cooperative or/and competitive conflict management approaches to achieve their goals. This thesis argues that different political st

Bark beetles face challenges and trade-offs during host selection, imposed by lethal tree defences, lower nutrition and higher competition in less well-defended trees, scarcity and ephemeral distribution of susceptible hosts, limitation of suitable hosts to one beetle generation, and relatively short lifespan and vulnerability of adults during host searching. Beetles contend with these challenges

To manage risks in Western society is increasingly seen as a process of including the public in different deliberative and/or participatory projects. This is sometimes done via civil society organisations (CSOs) that also have a second role as gatekeepers, managing or constraining flows of knowledge and information. This paper aims to analyse the dual role of CSOs in the management of chemical ris

We report on a two-color mid-infrared pump-probe spectroscopic study of the dynamics of the OH stretch vibrations of HDO molecules dissolved in a concentrated (10 M) solution of NaOD in D2O. We observe that spectral holes can be created in the broad OH stretch absorption band that change neither position nor width on a picosecond time scale. This behavior differs strongly from that of pure HDO:D2O

To process a stimulus as a holistic entity, the human brain must be able to conjoin its different features. Previous evidence suggests that this ability emerges during the first months of life, implying its considerable dependence on postnatal development. We recorded human newborn (1-3 days of age) electrical brain responses to frequently occurring (standard) sounds and to rarely occurring (devia

Brevmall Postal address Box 117, 221 00 Lund Visiting address Main University Building, Paradisgatan 2 Telephone +46 46-222 70 24, +46 46-222 00 00, +46 72-231 71 64 Email anna.akesson@rektor.lu.se Vice-Chancel lor Lund University’s Regulations for Elections to the Electoral College and Elections at Faculty and Department Level 3 November 2022 Reg. no STYR 2022/1481 DECISION 2 Contents Chapter 1.

https://www.staff.lu.se/sites/staff.lu.se/files/2024-03/lund-universitys-regulations-for-elections-to-the-electoral-college-and-elections-at-faculty-and-department-level.pdf - 2026-05-02

Everything you need to know about exchange studies Going abroad as an exchange student means spending a semester at one of LUSEM's partner universities. What is an exchange?Spending a semester abroad allows you to take advantage of excellent academic programmes around the globe. There are many benefits of going on an exchange:Gain a global education.Broaden your academic horizon by taking courses

https://www.lusem.lu.se/study/international-opportunities/studies-abroad-international-opportunities-lusem-students/exchange-studies-lusem-students - 2026-05-02

In this study we investigate the effect of programmed cross-flows on the error in the hydrodynamic radii (r(h)) determination with asymmetrical flow field-flow fractionation (AsFlFFF). Three different standard polystyrene particles (nominal radii of 30 and 40 and 50nm) are fractionated with exponentially and linearly decaying cross-flows with different decay rates. Hydrodynamic radii are calculate

Cold sensitivity is a common and persistent complaint after various hand injuries and diseases. The general aim of the thesis was to investigate the consequences of cold sensitivity for daily life in patients with traumatic hand injuries and hand-arm vibration syndrome (HAVS). To obtain a richer and more comprehensive picture reflecting the aim, studies with a quantitative and a qualitative design

Organometal halide perovskite-based solar cells have recently been reported to be highly efficient, giving an overall power conversion efficiency of up to 15%. However, much of the fundamental photophysical properties underlying this performance has remained unknown. Here, we apply photoluminescence, transient absorption, time-resolved terahertz and microwave conductivity measurements to determine

Attosecond pulses allow the study of electrons on their natural timescale. They are created from the interaction of atoms with ultrashort, intense laser pulses whose electric field approaches the strength of inner-atomic electric fields. This thesis presents experiments around the generation, characterization and application of attosecond pulses. First, we study the influence of the atomic genera

Popular Abstract in Swedish I många utvecklingsländer i tropiska klimat leder den snabba urbaniseringen till många problem, bl a försämrad termisk komfort i utemiljön. Detta har negativa följder för människors hälsa och välbefinnande och påverkar sociala och kommersiella aktiviteter utomhus negativt. Följaktligen är det mycket viktigt att åstadkomma komfortabla mikroklimat i urban miljö. Den huvuIn many developing tropical countries, rapid urban growth leads to several problems, including increased thermal stress. This has negative consequences for people's health and well-being, and affects social and commercial outdoor activities negatively. Consequently, the creation of thermally comfortable microclimates in urban environments is highly important. The main aim of this thesis is to dee

Aims: To show the power of history science methods for exposure assessment in occupational health studies, using the dry cleaning industry in Denmark around 1970 as the example. Methods: Exposure data and other information on exposure status were searched for in unconventional data sources such as the Danish National Archives, the Danish Royal Library, archives of Statistics Denmark, the National

The Homogeneous Charge Compression Ignition (HCCI) is the third alternative for combustion in the reciprocating engine. Here a homogeneous charge is used as in a spark-ignited engine, but the charge is compressed to autoignition as in a diesel. The main difference compared with the Spark Ignition (SI) engine is the lack of flame propagation and hence the independence from turbulence. Compared with

Background: While simultaneous saccharification and co-fermentation (SSCF) is considered to be a promising process for bioconversion of lignocellulosic materials to ethanol, there are still relatively little demo-plant data and operating experiences reported in the literature. In the current work, we designed a SSCF process and scaled up from lab to demo scale reaching 4% (w/v) ethanol using xylos

This study investigated the effect of glow discharge treatment of titania surfaces on plasma protein adsorption, by means of ellipsometry and mechanically assisted SDS elution. The adsorption and film elution of three plasma proteins, viz. human serum albumin (HSA), human immunoglobulin G (IgG) and laminin-1, as well as competitive adsorption from a mixture of the three proteins, showed that the a