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Introduction: ECG-derived vectorcardiography (VCG) has diagnostic and prognostic value in various diseases. Hypertrophic cardiomyopathy (HCM), a genetic disease with unexplained left ventricular hypertrophy, is one of the most common causes of sudden cardiac death (SCD) in young persons. Genotype positive status is associated with increased risk of systolic dysfunction, heart failure, and (SCD). H
PURPOSE: To study newly diagnosed glaucoma patients given mono- or multi-therapy regarding differences in initial intraocular pressure (IOP) reduction, target IOP levels reached and influence of untreated baseline IOP on IOP reduction.METHODS: Patients newly diagnosed with manifest primary open-angle glaucoma and included in the Glaucoma Intensive Treatment Study (GITS) were randomized to immediat
The trajectories of politically activist and socially committed interpretations of Islam in (late)modern societies continue to spur heated debate and academic discussion. A recurrent theme is the compatibility of Islamic ideological/legal foundations vis-à-vis secular state institutions and liberal democracy. Other debates concern rights and identity politics, problematizing the recognition of relThe trajectories of politically activist and socially committed interpretations of Islam in (late)modern societies continue to spur heated debate and academic discussion. A recurrent theme is the compatibility of Islamic ideological/legal foundations vis-à-vis secular state institutions and liberal democracy. Other debates concern rights and identity politics, problematizing the recognition of rel
Background: Environmental and genetic factors possibly trigger thyroid autoimmunity. Studies on perinatal risk factors for childhood thyroid autoimmunity are sparse.Objectives: The aim was to investigate if perinatal factors, family history of autoimmune diseases, and HLA-DQ genotypes contribute to thyroid autoimmunity in the Diabetes Prediction in Skåne (DiPiS) study.Methods: Samples from 1,874 t
Background: Perlecan is a heparan sulfate proteoglycan (HSPG) constituent of the extracellular matrix with roles in cell growth, differentiation, and angiogenesis. The role of the HS side chains in regulating invivo angiogenesis after hind-limb ischemia is unknown. Methods: Heparan sulfate (HS)-deficient perlecan (Hspg2 δ3/δ3
We present a complete set of helicity-dependent 2 → 3 antenna functions for QCD initial- and final-state radiation. The functions are implemented in the Vincia shower Monte Carlo framework and are used to generate showers for hadron-collider processes in which helicities are explicitly sampled (and conserved) at each step of the evolution. Although not capturing the full effects of spin correlatio
OBJECTIVE: To evaluate differences in clinical appearance and survival rates in patients operated on for adenocarcinoma in the distal esophagus with and without Barrett epithelium.DESIGN: Prospective clinical study.SETTING: University hospital, Sweden.PATIENTS: Fifty-four patients with adenocarcinoma in the distal esophagus with (n = 17) or without (n = 37) Barrett epithelium.INTERVENTION: Esophag
Background: Epidemiological data indicate decreased risk for development and growth of abdominal aortic aneurysm (AAA)among patients with diabetes mellitus (DM), but DM also goes with increased cardiovascular (CV)morbidity and mortality. We evaluated the effects of DM on mortality and CV morbidity after elective open AAA repair. Methods: This is a nationwide observational cohort study of patients
Hepatitis B virus (HBV) infection remains a major public health threat in the Middle East and North Africa (MENA). Phylogenetic analysis of HBV can be helpful to study the putative transmission links and patterns of inter-country spread of the virus. The objectives of the current study were to analyze the HBV genotype/sub-genotype (SGT) distribution, reverse transcriptase (RT), and surface (S) gen
Background: Pelvic exenteration for locally advanced rectal cancer (LARC) and locally recurrent rectal cancer (LRRC) is technically challenging but increasingly performed in specialist centres. The aim of this study was to compare outcomes of exenteration over time.Methods: This was a multicentre retrospective study of patients who underwent exenteration for LARC and LRRC between 2004 and 2015. Su
Polyphenolic compounds in bark are resources of great interest to produce renewable chemicals and several different technologies are available or under early development for the extraction of these types of compounds. Since critical environmental effects of a product are often set during the design phase, it is important to use life cycle assessment (LCA) to identify the steps resulting in the lar
Survival after blood or marrow transplantation (BMT) for inborn errors of metabolism (IEM) is excellent; however, the burden of morbidity in long-term survivors of BMT for IEM remains understudied. This study examined the risk of chronic health conditions (CHC) in ≥2-year survivors of allogeneic BMT for IEM performed between 1974 and 2014 using the BMT Survivor Study. In this retrospective cohort
Background: Turner syndrome (TS) is a complex genetic disorder with raised mortality. Our objective was to investigate mortality and causes of death in TS. Methods: A matched retrospective observational study of women with TS recruited from the Turner centers in Sweden were conducted. A total of 472 women with TS, ≥16 years old with a cytogenetically verified diagnosis and 2357 controls, matched f
Designing simulations for urban design not only requires explicit performance criteria of planning standards but a synthesis of implicit design objectives, that we will call 'purpose rules', with computational approaches. The former would at most lead to automation of the existing planning processes for speed and evaluation, the latter to an understanding of perceived urban qualities and their eff
This essay discusses the border between aggravated assault and attempted murder. This is discussed from the court's perspective and the aim is to examine how the judges decide whether or not the perpetrator has had the necessary intent to be held responsible for attempted murder. The essay includes two parts, one of which is theoretical and one that is practical. The theoretical part begins wi
In this master’s thesis we aim to answer whether the employees’ awareness of preservation has increased within the Swedish government agencies, on account of the new process oriented archival description developed by the Swedish National Archive. The process oriented archival description is based on the concept of describing archives on the outset of business processes, activities and transactions
Uppsatsen ämnar besvara hur företag arbetar för och rapporterar om verksamhetens jämställdhetsarbete, samt varför de väljer att offentliggöra verksamhetsarbetet genom hållbarhetsrapporter. För att besvara frågorna har såväl primär som sekundär data använts. En kvalitativ undersökning har genomförts av författarna, där information från 10 privatägda företag från olika branscher samlats in och sammaThe purpose of this essay is to examine how enterprises work towards greater gender equality and how they report about their work. It also aims to analyze why enterprises choose to compile these activities and measurements into official reports. In order to answer the questions asked in the essay, both primary and secondary data has been used. A qualitative survey has been conducted, where the aut
